The relationship between galectin-1 expression and the efficacy of anti-PD-1 therapy for non-small cell lung cancer patients [PDF]
Scientific ReportsWe herein examined the potential of galectin-1 expression to predict the efficacy of anti-PD-1 therapy for patients with non-small cell lung cancer (NSCLC).
Mari Tone +7 more
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Expression and significance of PIBF combined with Galectin-1 in cervical precancerous lesions [PDF]
Frontiers in MedicineObjectiveThis study aimed to discuss the significance of PIBF and Galectin-1 in cervical dysplasia tissue.MethodsThe expression of PIBF and Galectin-1 in precancerous tissues of cervical cancer was determined by the immunohistochemical method and ELISA ...
Hong Wang
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Galectin-1 Inhibition as a Strategy for Malignant Peripheral Nerve Sheath Tumor Treatment [PDF]
CellsNeurofibromatosis type 1 (NF1) is an inherited disorder that predisposes individuals to malignant peripheral nerve sheath tumors (MPNSTs), a highly aggressive sarcoma with limited treatment options and poor prognosis. This study explores the potential of
Hsiao-Chi Wang +6 more
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Therapeutic Targeting of the Galectin-1/miR-22-3p Axis Regulates Cell Cycle and EMT Depending on the Molecular Subtype of Breast Cancer [PDF]
CellsBreast cancer is a highly heterogeneous disease; hence, it is crucial to understand its biology and identify new targets for the development of effective treatments. Galectin-1 is known to play an oncogenic role in breast cancer progression.
Ju Yeon Kim +11 more
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Cardiorespiratory fitness and the association with galectin-1 in middle-aged individuals. [PDF]
PLoS ONEGalectin-1 plays a functional role in human metabolism and the levels are altered in obesity and type 2 diabetes (T2D). This study investigates the association of cardiorespiratory fitness (CRF) with galectin-1 and the interconnection with body fatness ...
Daniel Arvidsson +6 more
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Effect of galectin‐1 on prognosis and responsiveness of immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma [PDF]
Cancer MedicineBackground In renal cell carcinoma (RCC), no clinically available biomarker has been utilized for checkpoint inhibitor immunotherapy (IO) + tyrosine kinase inhibitor (TKI) combinations.
Jiajun Wang +5 more
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Feasibility of Serum Galectin-1 as a Diagnostic Biomarker for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Study on a Segment of the Chinese Population Using Convenience Sampling [PDF]
BiomedicinesBackground/Objectives: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is commonly considered as a hepatic manifestation of metabolic syndrome, posing considerable public health and economic challenges due to its high prevalence.
Ting Zeng +6 more
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Evaluation of galectins 1 and 3 expression in canine melanoma [PDF]
Pesquisa Veterinária Brasileira, 2021 : Canine melanoma is a frequently-occuring neoplasm in dogs and presents as malignant and highly metastatic in this context, studies that contribute to the understanding of the tumor microenvironment in melanoma include the role of galectins.
Jéssica S. Garcia +6 more
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Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy?
Frontiers in Oncology, 2022 The galectin family of proteins has high affinity with β-galactoside-containing glycans. These proteins participate in cell growth and differentiation, cell adhesion, cell signal transduction, cell apoptosis, and other cellular activities.
Yuanwei Shi +10 more
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Frontiers in Oncology, 2022 IntroductionTo investigate the role of tumor galectin-1 and galectin-3 in patients with lung adenocarcinoma after definitive radiation therapy.MethodsA total of 41 patients with localized lung adenocarcinoma undergoing thoracic radiation therapy without ...
Chun-Chieh Huang +11 more
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