Results 111 to 120 of about 27,415 (188)
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Background: Inflammatory bowel disease is a collection of illnesses that mainly affect the colon and small intestine, the most prevalent types being Crohn’s disease and ulcerative colitis. Carbohydrate-binding proteins (also known as galectins) have been
Arkan Khanjar Nasrullah +2 more
doaj +1 more source
Emerging Immune‐Based Therapeutic Strategies in Hepatocellular Carcinoma
ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide despite recent advances in systemic therapy. The introduction of immune checkpoint inhibitors has substantially expanded treatment options for advanced disease; however, durable responses are observed only in a subset of patients.
Janine Kah +2 more
wiley +1 more source
P022 Galectin-3, galectin-9, and galectin-3 binding protein in patients with inflammatory bowel diseases [PDF]
D Cibor, K Szczeklik, D Owczarek, T Mach
openaire +1 more source
Plasma-Derived Extracellular Vesicles Reveal Galectin-3 Binding Protein as Potential Biomarker for Early Detection of Glioma. [PDF]
Rana R +11 more
europepmc +1 more source
Fibroblast growth factor receptor 1 (FGFR1) is co‐translationally integrated into endoplasmic reticulum (ER) membranes and undergoes N‐glycosylation at several positions. This process is essential for FGFR1 progression through the secretory pathway.
Paulina Działek +5 more
wiley +1 more source
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu +3 more
wiley +1 more source
Curcumin – A Potent Inhibitor of Galectin-3 Expression
The expression of galectin-3, a b-galactoside binding lectin, was found to be affected by different kinds of stressors, and is strongly modified in numerous physiological and pathophysiological conditions.
Jerka Dumić +2 more
doaj
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source

