Results 11 to 20 of about 27,415 (188)

Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2. [PDF]

Mol Cell Proteomics, 2023
Abstract Human extracellular 6- O -endosulfatases Sulf-1 and Sulf-2 are the only enzymes that post-synthetically alter the 6- O sulfation of heparan sulfate proteoglycans (HSPG), which regulates interactions of HSPG with many proteins ...
Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Nováková Z, Bařinka C, Goldman R.   +6 more
europepmc   +6 more sources

Visualizing Galectin-3 Binding Protein Expression with ImmunoPET. [PDF]

Mol Pharm, 2023
Galectin-3 binding protein (Gal-3BP) is a glycoprotein that is overexpressed and secreted by several cancers and has been implicated as a marker of both tumor progression and poor prognosis in melanoma, non-small cell lung cancer, head and neck squamous cell carcinoma, and breast cancer.
Keinänen O, Sarrett SM, Delaney S, Rodriguez C, Dayts EJ, Capone E, Sauniere F, Ippoliti R, Sala G, Iacobelli S, Zeglis BM.   +10 more
europepmc   +4 more sources

Galectins, antibodies to them and galectin-3 binding protein in systemic lupus erythematosus

Научно-практическая ревматология
The study of galectins is provoked by the search for new biomarkers of activity, clinical manifestations, and disease outcomes of systemic lupus erythematosus (SLE). The presented literature review summarizes the data on the most well-known galectins-1, -
L. V. Kondratyeva, T. V. Popkova, E. L. Nasonov   +2 more
doaj   +2 more sources

Serum galectin-3 and galectin-3 binding protein levels in systemic lupus erythematosus and cutaneous lupus erythematosus. [PDF]

Postepy Dermatol Alergol, 2021
The roles of galectin-3 (Gal-3) and galectin-3 binding protein (G3BP) in systemic lupus erythematosus (SLE) are of ongoing interest, but the data are insufficient due to highly limited available studies. There are no data on cutaneous lupus erythematosus (CLE).To assess serum Gal-3 and G3BP concentrations in SLE patients with and without LE-specific ...
Kalinska-Bienias A, Kowalczyk E, Bienias P, Gala K, Jagielski P, Kowalewski C.   +5 more
europepmc   +5 more sources

Association of Serum Galectin-3-Binding Protein and Metabolic Syndrome in a Chinese Adult Population. [PDF]

Front Endocrinol (Lausanne), 2021
BackgroundGalectin-3-binding protein (GAL-3BP) is a ubiquitous and multifunctional secreted glycoprotein, which functions in innate immunity and has been highlighted as a potential mediator of adipose inflammation in obesity. In this study, we aimed to identify whether GAL-3BP is a novel biological marker for metabolic syndrome (MetS).MethodsThe ...
Zhen S, Cai R, Yang X, Ma Y, Wen D.
europepmc   +5 more sources

Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus. [PDF]

Lupus, 2023
Background Lupus nephritis (LN) is a major and severe organ involvement in systemic lupus erythematosus (SLE), whose diagnosis and treatment necessitate to perform kidney biopsy, which is an invasive procedure.
Faustini F, Idborg H, Fuzzi E, Larsson A, Lie WR, Pötzsch S, Okitsu SL, Svenungsson E, Gunnarsson I.   +8 more
europepmc   +4 more sources

Galectin-3-binding protein and future venous thromboembolism. [PDF]

Res Pract Thromb Haemost
Hansen ES, Edvardsen MS, Aukrust P, Ueland T, Hansen JB, Brækkan SK, Morelli VM.   +6 more
europepmc   +3 more sources

The role of galectin-3 and galectin-3-binding protein in venous thrombosis. [PDF]

Blood, 2015
Key PointsWe determined the location of gal3bp and gal3 and their role in promoting VT and leukocyte/endothelial cell interactions for the first time. Gal3bp and gal3 have the potential to be used as targets for future VT therapies.
DeRoo EP, Wrobleski SK, Shea EM, Al-Khalil RK, Hawley AE, Henke PK, Myers DD, Wakefield TW, Diaz JA.   +8 more
europepmc   +5 more sources

Characterization of Galectin Fusion Proteins with Glycoprotein Affinity Columns and Binding Assays

Molecules, 2023
Galectins are β-galactosyl-binding proteins that fulfill essential physiological functions. In the biotechnological field, galectins are versatile tools, such as in the development of biomaterial coatings or the early-stage diagnosis of cancer diseases ...
Carina Dey, Philip Palm, Lothar Elling
doaj   +1 more source

The two endocytic pathways mediated by the carbohydrate recognition domain and regulated by the collagen-like domain of galectin-3 in vascular endothelial cells. [PDF]

PLoS ONE, 2012
Galectin-3 plays an important role in endothelial morphogenesis and angiogenesis. We investigated the endocytosis of galectin-3 in human vascular endothelial cells and showed that galectin-3 could associate with and internalized into the cells in a ...
Xiaoge Gao, Dan Liu, Yuying Fan, Xinzhi Li, Huiting Xue, Yingyun Ma, Yifa Zhou, Guihua Tai   +7 more
doaj   +1 more source