Results 31 to 40 of about 43,794 (228)

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]

, 2002
The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora, Gabius, Hans-Joachim, Hercogová, Jana, Holíkova, Zuzana, Kaltner, Herbert, Motlik, Jan, Plzák, Jan, Smetana, Karel   +7 more
core   +1 more source

Galectin-3 interacts with the cell surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells [PDF]

, 2017
The galactoside-binding protein galectin-3 is increasingly recognized as an important player in cancer development, progression, and metastasis via its interactions with various galactoside-terminated glycans.
Beynon, R, Colomb, F, Rhodes, JM, Simpson, D, Wang, W, Yu, LG, Zafar, M   +6 more
core   +1 more source

Serum galectin 3, galectin 9 and galectin 3-binding proteins in patients with active and inactive inflammatory bowel disease. [PDF]

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2019
Galectins are lectins involved in physiological processes such as cell proliferation, apoptosis and migration, immune responses, inflammation, signalling, and angiogenesis. This study assessed the serum levels of galectin-3 (Gal-3) and galectin-3 (Gal-9) and galectin 3 binding protein (Gal-3BP), and evaluated their associations with the clinical ...
Cibor, Dorota, Szczeklik, Katarzyna, Brzozowski, Bartosz, Mach, Tomasz, Owczarek, Danuta   +4 more
openaire   +3 more sources

Phosphorylation of the β-Galactoside-binding Protein Galectin-3 Modulates Binding to Its Ligands [PDF]

Journal of Biological Chemistry, 2000
The beta-galactoside-binding protein galectin-3 has pleiotropic biological functions and has been implicated in cell growth, differentiation, adhesion, RNA processing, apoptosis, and malignant transformation. Galectin-3 may be phosphorylated at N-terminal Ser(6), but the role of phosphorylation in determining interactions of this endogenous lectin with
N, Mazurek, J, Conklin, J C, Byrd, A, Raz, R S, Bresalier   +4 more
openaire   +2 more sources

Pseudomonas aeruginosa lipopolysaccharide binds galectin-3 and other human corneal epithelial proteins [PDF]

Infection and Immunity, 1997
The aim of this study was to test whether galectin-3 is present in human corneal epithelium and whether lipopolysaccharide (LPS) purified from Pseudomonas aeruginosa ATCC 19660 binds to this animal lectin and/or to another human corneal epithelial protein(s) (HCEP) and to confirm which component of LPS (inner or outer core or lipid A) is important in ...
S K, Gupta, S, Masinick, M, Garrett, L D, Hazlett   +3 more
openaire   +2 more sources

Glycodendrimers and Modified ELISAs: Tools to Elucidate Multivalent Interactions of Galectins 1 and 3

Molecules, 2015
Multivalent protein-carbohydrate interactions that are mediated by sugar-binding proteins, i.e., lectins, have been implicated in a myriad of intercellular recognition processes associated with tumor progression such as galectin-mediated cancer cellular
Mark Wolfenden, Jonathan Cousin, Pratima Nangia-Makker, Avraham Raz, Mary Cloninger   +4 more
doaj   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Galectin-3-mediated glial crosstalk drives oligodendrocyte differentiation and (Re)myelination [PDF]

, 2018
Galectin-3 (Gal-3) is the only chimeric protein in the galectin family. Gal-3 structure comprises unusual tandem repeats of proline and glycine-rich short stretches bound to a carbohydrate-recognition domain (CRD).
Pasquini, Laura Andrea, Thomas, Laura
core   +1 more source

Acute hantavirus infection induces galectin-3-binding protein

Journal of General Virology, 2014
Hantaviruses are zoonotic viruses that cause life-threatening diseases when transmitted to humans. Severe hantavirus infection is manifested by impairment of renal function, pulmonary oedema and capillary leakage. Both innate and adaptive immune responses contribute to the pathogenesis, but the underlying mechanisms are not fully understood.
Vaheri Antti, Lankinen Hilkka, Sane Jussi, Hepojoki Jussi, Vapalahti Olli, Meri Seppo, Sironen Tarja, Strandin Tomas, Hetzel Udo, Vaheri Antti, Lankinen Hilkka, Sane Jussi, Hepojoki Jussi, Vapalahti Olli, Meri Seppo, Sironen Tarja, Strandin Tomas, Hetzel Udo, Tuntematon , Mustonen Jukka, Mäkelä Satu   +20 more
openaire   +3 more sources