Results 261 to 270 of about 4,689,501 (274)

Interleukin-1β stimulates galectin-9 expression in human astrocytes

Neuroreport, 2001
Galectin-9 is an eosinophil chemoattractant produced by activated T lymphocytes. We have addressed expression of galectin-9 in normal human astrocytes in culture. Expression of galectin-9 mRNA and protein were examined by reverse transcription-polymerase chain reaction (RT-PCR), Western blotting, and immunofluorescent staining.
H, Yoshida, T, Imaizumi, M, Kumagai, K, Kimura, C, Satoh, N, Hanada, K, Fujimoto, N, Nishi, K, Tanji, T, Matsumiya, F, Mori, X F, Cui, W, Tamo, T, Shibata, S, Takanashi, K, Okumura, T, Nakamura, K, Wakabayashi, M, Hirashima, Y, Sato, K, Satoh   +20 more
openaire   +2 more sources

Galectin-9 in tumor biology: A jack of multiple trades

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2013
Galectin family members have been shown to exert multiple roles in the context of tumor biology. Several recent findings support a similar multi-faceted role for galectin-9. Galectin-9 expression is frequently altered in cancer as compared to normal tissues.
Heusschen, Roy, Griffioen, Arjan, Thijssen, Victor   +2 more
openaire   +4 more sources

[Serum galectin-9 in cervical cancer].

Zhonghua yi xue za zhi, 2009
To investigate the expression level of Galectin-9 (Gal-9) in the serum of cervical cancer patients and analyze the clinic significance of it.Collected sera from 29 patients with cervical cancer, 45 patients with cervical inter-epithelial lesion (CIN) and 26 normal females. Determination of Gal-9 was performed by ELISA, and in the group of patients with
Mei-yan, Liang, Yan-ming, Lu, Yao, Zhang, Shu-lan, Zhang   +3 more
openaire   +1 more source

The ligation between ERMAP, galectin-9 and dectin-2 promotes Kupffer cell phagocytosis and antitumor immunity

Nature Immunology, 2023
Jie Li, Xiao-gang Liu, Rui-liang Ge, Yu Yin, Yong-da Liu, Wan-peng Lu, Mei Huang, Xue He, Jinghan Wang, Guoxiang Cai, Shu-han Sun, Ji-hang Yuan   +11 more
semanticscholar   +1 more source

T7 peptide-decorated exosome-based nanocarrier system for delivery of Galectin-9 siRNA to stimulate macrophage repolarization in glioblastoma

Journal of Neuro-Oncology, 2023
Chenguang Li, N. Guan, Feifei Liu
semanticscholar   +1 more source

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

Nature Immunology, 2005
Chen Zhu, A. Anderson, A. Schubart, H. Xiong, J. Imitola, S. Khoury, X. Zheng, T. Strom, V. Kuchroo   +8 more
semanticscholar   +1 more source

Elevated Galectin-9 across the human brain correlates with HIV neuropathology and detrimental cognitive states

Journal of Neurovirology, 2023
T. Premeaux, S. Yeung, S. Pillai, L. Ndhlovu   +3 more
semanticscholar   +1 more source

[Research progress on T-cell immunoglobulin mucin 3/galectin 9 (TIM-3/galectin-9) in tumour immunity].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
With the ongoing advancement of immune checkpoint research, targeting tumors through immune checkpoint blockade has emerged as a crucial approach in cancer therapy. T cell immunoglobulin and mucin-domain containing protein 3 (TIM-3) functions as a negative immune checkpoint.
Lanxin, Ma, Li, Bai
openaire   +1 more source

B7-H4 Binds Galectin-9 Glycosylation-Dependently and Attenuates Galectin-9-Mediated CD28/AKT Activation and T Cell Death

Abstract B7-H4, a member of the B7 family, is broadly expressed on various cancer cells and has been implicated in negative immune regulation, particularly in suppressing anti-tumor immunity. However, the receptor for B7-H4 and the molecular mechanisms underlying its immunoinhibitory effects remain poorly understood.
Ravear Zhiqiang Wang, Fang Yang, Jianhua Sui   +2 more
openaire   +1 more source

Galectin-9 (LGALS9)

Science-Business eXchange, 2011
openaire   +1 more source