Results 11 to 20 of about 34,736 (209)

Galectin-1 and Galectin-3 in Chronic Pancreatitis [PDF]

Laboratory Investigation, 2000
Galectin-1 and galectin-3 have important functions in cell-cell interactions, cell adhesion to extracellular matrix, the organization of extracellular matrix, and tissue remodeling. To assess their potential role in chronic pancreatitis (CP), we examined their expression by Northern blot analysis, in situ hybridization, immunohistochemistry, and ...
L, Wang, H, Friess, Z, Zhu, L, Frigeri, A, Zimmermann, M, Korc, P O, Berberat, M W, Büchler   +7 more
openaire   +2 more sources

Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage

Frontiers in Cellular Neuroscience, 2019
Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack, Sangeetha Sukumari-Ramesh   +1 more
doaj   +1 more source

Intensity and Grading of Galectin-3 Expression as a Sole Marker to Differentiate Benign and Malignant Thyroid Neoplasms

National Journal of Laboratory Medicine, 2019
Introduction: Errors in categorization of thyroid neoplasms as benign or malignant has management implications. In several studies Galectin-3 was one of the most reliable markers for malignancy in thyroid.
Pallavi Vijay Borkar, Kondisetty Gowrinath, Kondisetty Sandeep   +2 more
doaj   +1 more source

Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein

Journal of Biomedical Science, 2023
Background Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly conserved among influenza A virus ...
Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang, Hao-Earn Chong, Nai-Hui Chung, Chia-Hsing Leu, Fu-Tong Liu, Michael M. C. Lai, Pin Ling, Chao-Liang Wu, Ai-Li Shiau   +10 more
doaj   +1 more source

Galectin-3 and the skin [PDF]

Journal of Dermatological Science, 2011
Galectin-3 is highly expressed in epithelial cells including keratinocytes and is involved in the pathogenesis of inflammatory skin diseases by affecting the functions of immune cells. For example, galectin-3 can contribute to atopic dermatitis (AD) by promoting polarization toward a Th2 immune response by regulating dendritic cell (DC) and T cell ...
Larissa, Larsen, Huan-Yuan, Chen, Jun, Saegusa, Fu-Tong, Liu   +3 more
openaire   +2 more sources

Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation

Frontiers in Molecular Neuroscience, 2017
Galectin-3, a member of the galectin protein family, has been found to regulate cell proliferation, inhibit apoptosis and promote inflammatory responses.
Yan-Chu Chen, Yun-Li Ma, Cheng-Hsiung Lin, Sin-Jhong Cheng, Sin-Jhong Cheng, Wei-Lun Hsu, Eminy H.-Y. Lee, Eminy H.-Y. Lee   +7 more
doaj   +1 more source

Human galectin-1 and galectin-3 promote Tropheryma whipplei infection [PDF]

Gut Microbes, 2021
Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple's disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have shown that T. whipplei harbors complex surface glycoproteins with evidence of sialylation. However, the exact contribution
Ayona, Diyoly, Zarza, Sandra Madariaga, Landemarre, Ludovic, Roubinet, Benoît, Decloquement, Philippe, Raoult, Didier, Fournier, Pierre-Edouard, Desnues, Benoit   +7 more
openaire   +4 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Circulating Galectin-3 Evaluation in Dogs With Cardiac and Non-cardiac Diseases

Frontiers in Veterinary Science, 2021
Galectin-3 is involved in important biological functions such as fibrogenesis and inflammation. Notably, it is associated with various diseases and plays a major role in cardiac inflammation and fibrosis.
Ga-Won Lee, Min-Hee Kang, Woong-Bin Ro, Doo-Won Song, Hee-Myung Park   +4 more
doaj   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source