Results 21 to 30 of about 18,892,704 (362)
Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
Cell Death and Disease, 2022 The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are inherently associated with disease conditions.
J. García-Revilla +8 more
semanticscholar +1 more source
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +8 more sources
Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients
Scientific Reports, 2021 Severe COVID-19 is associated with a systemic hyperinflammatory response leading to acute respiratory distress syndrome (ARDS), multi-organ failure, and death.
Eduardo Cervantes-Alvarez +17 more
semanticscholar +1 more source
Heliyon, 2023 Introduction: There is still a lack of sensitive predictive tools for stroke outcomes. High galectin-3 concentration is associated with an increased risk of stroke.
Xiaoling Han +11 more
doaj +1 more source
The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase. [PDF]
PLoS ONE, 2011 Expression of galectin-3 is associated with sarcoma progression, invasion and metastasis. Here we determined the role of extracellular galectin-3 on migration of sarcoma cells on laminin-111.
Fabiana H M Melo +7 more
doaj +1 more source
Physical tuning of galectin-3 signaling
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The family of carbohydrate-binding proteins known as galectins receive considerable attention for their ability to modulate cell behavior in both normal and pathological settings.
Shaheen A. Farhadi +4 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Cytosolic lipopolysaccharides (LPSs) induce oligomerization of caspase-4/5/11, resulting in pyroptosis, but the involvement of any other host resistance factors in this process is unknown.
Tzu-Han Lo +8 more
semanticscholar +1 more source
Assessment of serum galectin-3 levels in acute rheumatic fever
The Turkish Journal of Pediatrics, 2022 Background. Galectin-3 is a biomarker which takes a role in both acute and chronic inflammation as well as fibrosis and oxidative stress. Increased levels of it are associated with cardiovascular diseases.
Serdar Epçaçan +3 more
doaj +1 more source
The Role of Galectin-3 and ST2 in Cardiology: A Short Review
Biomolecules, 2021 Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload.
A. Merino-Merino +4 more
semanticscholar +1 more source
The role of salivary galectin-3 and galectin-9 levels in plaque-induced gingivitis and periodontitis
Heliyon, 2023 Background: This study aimed to compare the salivary galectin-3 and galectin-9 levels in periodontitis, gingivitis, and periodontally healthy patients. Methods: This study included 75 non-smokers who were systemically healthy.
Zerrin Barut +6 more
doaj +1 more source