FASN regulates cellular response to genotoxic treatments by increasing PARP-1 expression and DNA repair activity via NF-κB and SP1 [PDF]
Fatty acid synthase (FASN), the sole cytosolic mammalian enzyme for de novo lipid synthesis, is crucial for cancer cell survival and associates with poor prognosis. FASN overexpression has been found to cause resistance to genotoxic insults.
Barlow, Lincoln James +8 more
core +1 more source
Penta-1,2,3,4,6-O-Galloyl-β-d-Glucose Inhibits UVB-Induced Photoaging by Targeting PAK1 and JNK1
Penta-O-galloyl-β-d-glucose (PGG) is a gallotannin polyphenolic compound that occurs naturally in fermented Rhus verniciflua. The present study aimed to examine the effect of PGG on UVB-induced skin aging and its molecular mechanisms in HaCaT human ...
Ji-An Kim +4 more
doaj +1 more source
GALLOTANNINS FROM QUERCUS ROBUR CULTIVATED IN EGYPT
Four gallotannins: 1,2,3-tri-O-galloyl-b-glucose; 1,2,3,6-tetra-O-galloyl-b-D-glucose; 1,2,3,4,6-penta-O-galloyl-b-D-glucose and 1,2,3,4,6-penta-O-galloyl-a-D-glucose, together with gallic acid and methoxy gallic acid have been isolated from the seeds of Quercus robur and their stuctures were elucidated on the basis of chemical and spectral evidence.
Salwa Farag +2 more
openaire +1 more source
Acorn Poisoning as a Potential Threat to Animals
The acorn is the nut of oak trees (genera Quercus and Lithocarpus) that can be found in the Northern Hemisphere. They are a valuable source of food for many animals (birds, rats, squirrels, pigs), but can pose health risks when consumed in large ...
Andreia Garcês +2 more
doaj +1 more source
Effect of polyethylene glycol on in vitro gas production kinetics of Prosopis cineraria leaves at different growth stages [PDF]
The aim of this experiment was to determine the effect of polyethylene glycol (PEG) on in vitro gas production (GP) kinetics of Prosopis cineraria leaves at different growth stages.
CERRILLO SOTO, MARIA ANDREA +13 more
core
THE QUALITATIVE CHARACTERISTIC OF PHENOLiC SUBSTANCES IN ADAPTOGENIC REMEDY
The basic phenolic compounds of components of the adaptogenic remedy Adaptophyte were identified by using thin layer chromatographic method with corresponding mobile phases that allow to confirm presence herb of Polygonum, aviculare L.
P. B. Lubsandorzhiyeva
doaj
A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. [PDF]
Senescence is a universal barrier to immortalisation and tumorigenesis. As such, interest in the use of senescence-induction in a therapeutic context has been gaining momentum in the past few years; however, senescence and immortalisation remain ...
A Groth +68 more
core +3 more sources
Polyphenols are categorized as plant secondary metabolites, and they have attracted much attention in relation to human health and the prevention of chronic diseases.
Kyuichi Kawabata +2 more
doaj +1 more source
Biomolekuláris NMR: Szerkezet, oligomerizáció, mozgás és molekuláris felismerési jelenségek glikopeptid antibiotikumokban, cukrokban és kalcium kötő fehérjékben = Biomolecular NMR: Structure, oligomerization, dynamics and molecular recognition of glycopeptide antibiotics, carbohydrates and calcium binding proteins [PDF]
Olyan új NMR módszereket dolgoztunk ki, amellyekkel molekulák térszerkezetét és mozgását a korábbiaknál pontosabban tudjuk leírni. A módszerek a spin-spin csatolási állandó mérésén és a relaxációs jelenségen alapulnak.
Batta, Gyula +2 more
core
Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy [PDF]
Additional file: Figure S1. The effect of combination of Peph phenolic compounds on proliferation of LS174 cells compared to total Peph extract. Human colon adenocarcinoma LS174 cells were treated for 72Â h with different combinations (A. 3 combinations,
Habib Karoui +6 more
core +4 more sources

