Results 41 to 50 of about 10,537 (260)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BMC Psychology, 2023 Background Online game addiction has become a prominent public concern, particularly among emerging adults, warranting in-depth investigation. Despite prior cross-sectional research indicating a negative correlation between gratitude and online gaming ...
Bin Gao +4 more
doaj +1 more source
Hubungan antara Kecanduan Game Internet dengan Keterampilan Sosial pada Remaja di Kota Yogyakarta
Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal), 2022 Background: Most Indonesians are internet users. Adolescents, who are active internet users and use internet for playing game too often, have the risk of experiencing online gaming addiction. Internet game addict may possess poor social skills. Objective:
Devina Ngeksi Hari Laksono +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Relative Deprivation and Game Addiction in Left-Behind Children: A Moderated Mediation
Frontiers in Psychology, 2021 Previous findings show that relative deprivation has a profound influence on game addiction, but the potential mediating and moderating mechanisms are unclear, especially for left-behind children.
Banglin Yang +6 more
doaj +1 more source
Community Based Medical Journal, 2017 Abstract not available CBMJ 2017 January: Vol. 06 No.
openaire +2 more sources
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Newest Findings On Gaming Addiction Treatment [PDF]
Journal of Education, Health and Sport, 2018 Golebiowska Maria, Golebiowska Beata. Newest findings on gaming addiction treatment. Journal of Education, Health and Sport. 2018;8(8):112-122. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1298732 http://ojs.ukw.edu.pl/index.php/johs/article/view/5608 https://pbn.nauka.gov.pl/sedno-webapp/works/868645 The journal has had 7 ...
Maria Golebiowska, Beata Golebiowska
openaire +3 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source