Results 91 to 100 of about 9,642 (218)

Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

eLife
It is currently unknown whether all Plasmodium falciparum-infected mosquitoes are equally infectious. We assessed sporogonic development using cultured gametocytes in the Netherlands and naturally circulating strains in Burkina Faso.
Chiara Andolina, Wouter Graumans, Moussa Guelbeogo, Geert-Jan van Gemert, Jordache Ramijth, Soré Harouna, Zongo Soumanaba, Rianne Stoter, Marga Vegte-Bolmer, Martina Pangos, Photini Sinnis, Katharine Collins, Sarah G Staedke, Alfred B Tiono, Chris Drakeley, Kjerstin Lanke, Teun Bousema   +16 more
doaj   +1 more source

Spatial Distribution and Host‐Specific Patterns of Avian Haemosporidian Infections in a Semi‐Arid Region of Northeastern Iran

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A survey of 263 birds across 10 species in Semnan Province, Iran, revealed a 22.1% prevalence of avian haemosporidian infections, dominated by Haemoproteus spp. Pigeons showed significantly higher infection risk. Spatial analysis identified clustering in Shahroud County, suggesting local climatic and ecological conditions influence parasite ...
Seyed‐Reza Mirbadie, Rasoul Alimi, Eissa Soleymani, Naghmeh Dastan, Abdolmajid Gholizadeh, Amir‐Hossein Maghsood, Mohammad‐Ali Mohaghegh   +6 more
wiley   +1 more source

Gametocyte sex ratio: the key to understanding Plasmodium falciparum transmission? [PDF]

, 2019
A mosquito needs to ingest at least one male and one female gametocyte to become infected with malaria. The sex of Plasmodium falciparum gametocytes can be determined microscopically but recent transcriptomics studies paved the way for the development of
Meerstein-Kessel, Lisette, Bousema, T., Bousema, Teun, Gonçalves, Bronner P, Tadesse, F.G., Meerstein-Kessel, L., Tadesse, Fitsum G, Ranford-Cartwright, L., Ranford-Cartwright, Lisa, Drakeley, Chris, Drakeley, C., Goncalves, B.P., Tadesse, Fitsum G.   +12 more
core   +2 more sources

Challenging the Clinical Paradigm of Hepatozoon canis: A Primary Pathogen Causing Clinically Significant Disease at Low Parasitaemia and a Chronic Inflammatory State

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Hepatozoon canis causes significant clinical disease even at low parasitaemia and induces chronic subclinical anaemia and inflammation in dogs. Lack of tick control is the main modifiable risk factor. Molecular diagnosis is far more sensitive than microscopy, challenging the traditional view that disease severity depends solely on parasite burden ...
Somayeh Bahrami, Zahra Mashayekhi, Seyedeh Misagh Jalali, Mohammad Khosravi, Mohammad Rajabloo   +4 more
wiley   +1 more source

The sex ratio of Plasmodium gametocytes

Parasitology, 1989
SUMMARYSex ratio theory usually predicts an equilibrium sex ratio and equal proportions of males and females in a population, including the progenitors of the reproductive cells of protozoans. This proposal was tested with three species of malarial parasites of lizards, Plasmodium mexicanum of the western fence lizard, and P. agamae and P. giganteum of
openaire   +2 more sources

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

, 2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G, Jawara, M, Doherty, T, Milligan, P, von Seidlein, L, Sutherland, C, Drakeley, C, Coleman, R, Pinder, M, Walraven, G, Deen, J   +10 more
core   +1 more source

Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings.

PLoS Pathogens, 2018
Malaria transmission remains high in Sub-Saharan Africa despite large-scale implementation of malaria control interventions. A comprehensive understanding of the transmissibility of infections to mosquitoes may guide the design of more effective ...
André Lin Ouédraogo, Philip A Eckhoff, Adrian J F Luty, Will Roeffen, Robert W Sauerwein, Teun Bousema, Edward A Wenger   +6 more
doaj   +1 more source

A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

eLife, 2018
Background: Malaria elimination strategies require a thorough understanding of parasite transmission from human to mosquito. A clinical model to induce gametocytes to understand their dynamics and evaluate transmission-blocking interventions (TBI) is ...
Isaie J Reuling, Lisanne A van de Schans, Luc E Coffeng, Kjerstin Lanke, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan van Gemert, Karina Teelen, Rianne Siebelink-Stoter, Marga van de Vegte-Bolmer, Quirijn de Mast, André J van der Ven, Karen Ivinson, Cornelus C Hermsen, Sake de Vlas, John Bradley, Katharine A Collins, Christian F Ockenhouse, James McCarthy, Robert W Sauerwein, Teun Bousema   +20 more
doaj   +1 more source

Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.

, 2004
OBJECTIVES: Combination therapy using existing anti-malarials together with artesunate (AS) has been advocated as a method to slow the spread of drug resistance.
Sutherland, Colin J, Obisike, Uche, Drakeley, Christopher J, Walraven, Gijs, Targett, Geoffrey AT, Jawara, Musa, Coleman, Rosalind, Pinder, Margaret   +7 more
core   +1 more source

Gametocyte clearance in children, from western Kenya, with uncomplicated Plasmodium falciparum malaria after artemether–lumefantrine or dihydroartemisinin–piperaquine treatment

Malaria Journal, 2019
Background The efficacy and safety of artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DP) against asexual parasites population has been documented.
Protus Omondi, Marion Burugu, Damaris Matoke-Muhia, Edwin Too, Eva A. Nambati, William Chege, Kelvin B. Musyoka, Kelvin Thiongo, Maureen Otinga, Francis Muregi, Francis Kimani   +10 more
doaj   +1 more source