Results 81 to 90 of about 13,563 (220)

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

, 2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G, Drakeley, C, Jawara, M, von Seidlein, L, Coleman, R, Deen, J, Pinder, M, Doherty, T, Sutherland, C, Walraven, G, Milligan, P   +10 more
core   +1 more source

Declining Burden of Malaria Over two Decades in a Rural Community of Muheza District, North-Eastern Tanzania. [PDF]

, 2013
The recently reported declining burden of malaria in some African countries has been attributed to scaling-up of different interventions although in some areas, these changes started before implementation of major interventions.
A Bhattarai, AC Ghani, AM Ronn, AS Rutta, BA Okech, BL Sharp, BP Mmbando, Bruno P Mmbando, C Karema, C Lengeler, Deus S Ishengoma, DS Ishengoma, DW Meyrowitsch, E Chizema-Kawesha, EA Okiro, EA Okiro, FO ter Kuile, G Mtove, G O'Connor, H Reyburn, HD Teklehaimanot, I Kleinschmidt, I Kleinschmidt, Ib C Bygbjerg, J Mufunda, J Picard, JC Beier, JP Lusingu, KI Barnes, M Alifrangis, M Lemnge, M Otten, Martha M Lemnge, Method D Segeja, MH Craig, MH Craig, Michael Alifrangis, Ministry of Health, Ministry of Health, MK Bouyou-Akotet, MM Lemnge, MM Lemnge, MS Hsiang, MW Aregawi, National Malaria Control Programme, P Chanda, P Winskill, PH Jakobsen, PM Graves, PM Nyarango, R Maharaj, RJ Manuel, RW Steketee, SJ Ceesay, SJ Ceesay, SM Magesa, T Bousema, T Jelinek, T Jelinek, VA Kilimali, WHO, WHO, WHO, WP O'Meara, WP O'Meara, YA Derua   +65 more
core   +2 more sources

Strong Cross‐Reactivity of Anti–Plasmodium falciparum pLDH Monoclonal Antibodies With Plasmodium malariae pLDH in the Abbott Bioline Malaria Ag P.f/P.f/P.v Rapid Diagnostic Test

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives This study aimed to describe the cross‐reactivity of the Abbott Bioline Malaria Ag P.f/P.f/P.v rapid diagnostic test, designed to detect Plasmodium falciparum and P. vivax, with other Plasmodium species, based on the detection of parasite lactate dehydrogenase enzymes.
Gabriel Montoia, Maria Carmen Arroyo Sanchez, Giselle Lima‐Cooper, Maria de Lourdes Rego Neves Farinas, Juliana Inoue, Silvia Maria Di Santi   +5 more
wiley   +1 more source

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage [PDF]

Malaria Journal, 2015
Plasmodium falciparum sexual development plays a fundamental role in the transmission and spread of malaria. The ability to generate gametocytes can be lost during culture in vitro, often associated with the loss of a subtelomeric region of chromosome 9. Gametocytogenesis starts with erythrocyte invasion by a sexually committed merozoite, but the first
Tiburcio, M, Dixon, MWA, Looker, O, Younis, SY, Tilley, L, Alano, P   +5 more
openaire   +3 more sources

Epidemiology of Malaria in an Area Prepared for Clinical Trials in Korogwe, North-eastern Tanzania. [PDF]

, 2009
Site preparation is a pre-requesite in conducting malaria vaccines trials. This study was conducted in 12 villages to determine malariometric indices and associated risk factors, during long and short rainy seasons, in an area with varying malaria ...
Acleus S Rutta, AE Mnzava, AM Ronn, Bruno P Mmbando, CA Maxwell, CJ Drakeley, CJ Drakeley, Deus S Ishengoma, DG Heppner Jr, E Kahigwa, Filbert Francis, H Dirren, Hamisi A Msangeni, J Keiser, JC Beier, JG Siri, JP Lusingu, JP Lusingu, JP Shott, KN Suh, M Alifrangis, Martha M Lemnge, Mathias L Kamugisha, Method D Segeja, Misago D Seth, PB Bloland, R Bodker, R Bodker, RW Snow, S Vyas, Samwel H Sembuche, V Robert, WL Kilama, WL Kilama   +33 more
core   +3 more sources

Production of Plasmodium falciparum Gametocytes In Vitro [PDF]

, 2012
Production of gametocytes in vitro is essential for studies of Plasmodium falciparum sexual stages. Here, we describe procedures for the high-yield production and fractionation of P. falciparum gametocytes stages I to V.
Kathryn Shaw, Saliba, Marcelo, Jacobs-Lorena   +1 more
openaire   +2 more sources

Detecting Gametocytes: How Sensitive Is Sensible? [PDF]

The Journal of Infectious Diseases, 2017
Contains fulltext : 190622.pdf (Publisher’s version ) (Open Access)
Meerstein-Kessel, L., Meerstein-Kessel, L., Bousema, T., Stone, W.J.   +3 more
openaire   +3 more sources

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

Malaria Journal, 2017
Background Transmission of malaria from man to mosquito depends on the presence of gametocytes, the sexual stage of Plasmodium parasites in the infected host.
Tamirat Gebru, Anthony Ajua, Michael Theisen, Meral Esen, Ulysse Ateba Ngoa, Saadou Issifou, Ayola A. Adegnika, Peter G. Kremsner, Benjamin Mordmüller, Jana Held   +9 more
doaj   +1 more source

The WD40-Protein PfWLP1 Ensures Stability of the PfCCp-Based Adhesion Protein Complex in Plasmodium falciparum Gametocytes

Frontiers in Cellular and Infection Microbiology, 2022
Members of the WD40-repeat protein family can be found in all eukaryotic proteomes where they usually serve as interaction platforms for the assembly of large protein complexes and are therefore essential for the integrity of these complexes.
Lena Roling, Ansgar Flammersfeld, Gabriele Pradel, Sandra Bennink   +3 more
doaj   +1 more source