Results 71 to 80 of about 13,563 (220)

Sex-partitioning of the Plasmodium falciparum stage V gametocyte proteome provides insight into falciparum-specific cell biology [PDF]

, 2014
One of the critical gaps in malaria transmission biology and surveillance is our lack of knowledge about Plasmodium falciparum gametocyte biology, especially sexual dimorphic development and how sex ratios that may influence transmission from the human ...
Dinglasan, R. R., Goldowitz, I., Graham, D. R., King, J. G., Marti, M., Mathias, D. K., Moss, E., Pastrana-Mena, R., Tao, D., Tripathi, A., Ubaida-Mohien, C.   +10 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Plasmodium falciparum Spatial Analysis, Western Kenya Highlands

Emerging Infectious Diseases, 2005
We carried out a population-based study to determine the unbiased, age-specific Plasmodium falciparum prevalence, asexual and sexual parasite density, and spatial distribution to establish rates of infection at a site in western Kenya.
Otsyula G. Munyekenye, Andrew Githeko, Guofa Zhou, Emmanuel Mushinzimana, Noboru Minakawa, Guiyun Yan   +5 more
doaj   +1 more source

Persistent Plasmodium falciparum infections enhance transmission-reducing immunity development

Scientific Reports, 2021
Subclinical infections that serve as reservoir populations to drive transmission remain a hurdle to malaria control. Data on infection dynamics in a geographical area is required to strategically design and implement malaria interventions.
Ruth Ayanful-Torgby, Esther Sarpong, Hamza B. Abagna, Dickson Donu, Evans Obboh, Benedicta A. Mensah, Joshua Adjah, Kim C. Williamson, Linda E. Amoah   +8 more
doaj   +1 more source

The Plasmodium falciparum CCCH Zinc Finger Protein ZNF4 Plays an Important Role in Gametocyte Exflagellation through the Regulation of Male Enriched Transcripts

Cells, 2022
CCCH zinc finger proteins (ZFPs) function mainly as RNA-binding proteins (RBPs) and play a central role in the mRNA metabolism. Over twenty seven CCCH-ZFPs are encoded in the genome of the human malaria parasite Plasmodium falciparum, the causative agent
Borja Hanhsen, Afia Farrukh, Gabriele Pradel, Che Julius Ngwa   +3 more
doaj   +1 more source

Capacity strengthening in malaria research: the Gates Malaria Partnership.

, 2006
The Gates Malaria Partnership (GMP) includes five African and four European partner institutions. Its research programme has five priority areas involving an extensive range of field-based studies.
Bhasin, Amit, Bowler, Cathy H, Greenwood, Brian M, Naylor, Heather, Targett, Geoffrey A   +4 more
core   +1 more source

Critical Steps of Plasmodium falciparum Ookinete Maturation [PDF]

, 2020
The egress and fertilization of Plasmodium gametes and development of a motile ookinete are the first crucial steps that mediate the successful transmission of the malaria parasites from humans to the Anopheles vector. However, limited information exists
Alano, P., Costa, G., Levashina, E., Siciliano, G., Suárez-Cortés, P., Valleriani, A.   +5 more
core   +1 more source

A multiplex assay to detect mosquito species, bloodmeal host source and Plasmodium in malaria vectors using Nanopore amplicon sequencing

Medical and Veterinary Entomology, EarlyView.
Insectary‐reared mosquitoes were simultaneously assessed for species identification, bloodmeal source analysis and Plasmodium detection, using a single multiplexed sequencing run on the MinION sequencing platform. The method was applied to 150 insectary‐reared mosquitoes, representing nine species blood‐fed with five vertebrate hosts and 40 samples for
E. Abby Rogers, Dieunel Derilus, Christopher Sandi, Lisa Reimer, Audrey Lenhart, Lucy Mackenzie Impoinvil   +5 more
wiley   +1 more source

Strategies for Detection of Plasmodium species Gametocytes

PLoS ONE, 2013
Carriage and density of gametocytes, the transmission stages of malaria parasites, are determined for predicting the infectiousness of humans to mosquitoes. This measure is used for evaluating interventions that aim at reducing malaria transmission.
Wampfler, R, Mwingira, F, Javati, S, Robinson, L, Betuela, I, Siba, P, Beck, H-P, Mueller, I, Felger, I   +8 more
openaire   +6 more sources

Plasmodium falciparum Gametocyte Enrichment in Peripheral Blood Samples by Magnetic Fractionation: Gametocyte Yields and Possibilities to Reuse Columns [PDF]

The American Journal of Tropical Medicine and Hygiene, 2019
Gametocytes are sexual stage malaria parasites responsible for transmission to mosquitoes. Multiple gametocyte-producing clones may be present in natural infections, but the molecular characterization of gametocytes is challenging. Because of their magnetic properties, gametocyte enrichment can be achieved by magnetic fractionation.
Graumans, Wouter, Andolina, Chiara, Awandu, Shehu S., Grignard, Lynn, Lanke, Kjerstin, Bousema, Teun   +5 more
openaire   +5 more sources