Results 51 to 60 of about 803 (130)

Plasmodium falciparum gametocyte carriage, emergence, clearance and population sex ratios in anaemic and non-anaemic malarious children

Memorias do Instituto Oswaldo Cruz, 2011
Anaemia in falciparum malaria is associated with an increased risk of gametocyte carriage, but its effects on transmission have not been extensively evaluated in malarious children.
Grace Olusola Gbotosho, Akintunde Sowunmi, Titilope Modupe Okuboyejo, Christian Tientcha Happi, Obaro Stanley Michael, Onikepe Abiola Folarin, Elsie Olufunke Adewoye   +6 more
doaj   +1 more source

Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin

Cytoskeleton, Volume 83, Issue 7, Page 479-483, July 2026.
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel, Friedrich Frischknecht, Matthias Marti   +2 more
wiley   +1 more source

Spatial Distribution and Host‐Specific Patterns of Avian Haemosporidian Infections in a Semi‐Arid Region of Northeastern Iran

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A survey of 263 birds across 10 species in Semnan Province, Iran, revealed a 22.1% prevalence of avian haemosporidian infections, dominated by Haemoproteus spp. Pigeons showed significantly higher infection risk. Spatial analysis identified clustering in Shahroud County, suggesting local climatic and ecological conditions influence parasite ...
Seyed‐Reza Mirbadie, Rasoul Alimi, Eissa Soleymani, Naghmeh Dastan, Abdolmajid Gholizadeh, Amir‐Hossein Maghsood, Mohammad‐Ali Mohaghegh   +6 more
wiley   +1 more source

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage [PDF]

Malaria Journal, 2015
Plasmodium falciparum sexual development plays a fundamental role in the transmission and spread of malaria. The ability to generate gametocytes can be lost during culture in vitro, often associated with the loss of a subtelomeric region of chromosome 9. Gametocytogenesis starts with erythrocyte invasion by a sexually committed merozoite, but the first
Tiburcio, M, Dixon, MWA, Looker, O, Younis, SY, Tilley, L, Alano, P   +5 more
openaire   +3 more sources

Defining the signature of deformable and infectious Plasmodium falciparum gametocytes [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background One of the major challenges for malaria elimination is combating the highly efficient spread of the disease. Despite progress in understanding the development of malaria transmission stages, there remain many unanswered questions about how ...
Martijn Huijnen, Teun Bousema, Sanna Rijpma, Wouter Graumans, Matthias Marti, Dario Beraldi, Kathryn crouch, Lisette Meerstein-Kessel, Geert-Jan van Gemert, Deepali Ravel, Armin Passecker, Emmanuel Arinaitwe, Sara Lynn Blanken, Priscilla Ngotho, Stoter Rianne, Daniel Neafsey, Till Voss   +16 more
doaj   +1 more source

Challenging the Clinical Paradigm of Hepatozoon canis: A Primary Pathogen Causing Clinically Significant Disease at Low Parasitaemia and a Chronic Inflammatory State

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Hepatozoon canis causes significant clinical disease even at low parasitaemia and induces chronic subclinical anaemia and inflammation in dogs. Lack of tick control is the main modifiable risk factor. Molecular diagnosis is far more sensitive than microscopy, challenging the traditional view that disease severity depends solely on parasite burden ...
Somayeh Bahrami, Zahra Mashayekhi, Seyedeh Misagh Jalali, Mohammad Khosravi, Mohammad Rajabloo   +4 more
wiley   +1 more source

Antibodies to PfsEGXP, an Early Gametocyte-Enriched Phosphoprotein, Predict Decreased Plasmodium falciparum Gametocyte Density in Humans [PDF]

The Journal of Infectious Diseases, 2018
Antigametocyte-specific immune responses may regulate Plasmodium falciparum gametocyte density, providing the rationale for pursuing transmission-blocking vaccines (TBVs) that target gametocytes in the human host.To identify novel antigametocyte TBV antigens, we interrogated the gametocyte proteome with our whole proteome differential screening method ...
Christian P Nixon, Christina E Nixon, Ian C Michelow, Rayna A Silva-Viera, Bonnie Colantuono, Aisha S Obeidallah, Ambrish Jha, Dominique Dockery, Dipak Raj, Sangshin Park, Patrick E Duffy, Jonathan D Kurtis   +11 more
openaire   +2 more sources

The inducible gametocyte producer (iGP1) strain is well-suited to produce both immature and mature gametocytes for subsequent drug sensitivity profiling

Frontiers in Cellular and Infection Microbiology
Advancing toward malaria eradication requires compounds that target both asexual blood-stage parasites to treat the disease as well as gametocytes to reduce transmission.
Thomas Martin Schäfer, Lais Pessanha de Carvalho, Fatih D. Darende, Daniel Stopper, Finn K. Hansen, Jana Held, Jana Held, Jana Held   +7 more
doaj   +1 more source

Single‐Cell Transcriptomics and Development of Gametocyte‐Specific Molecular Markers for Avian Malaria Parasites

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Avian malaria, caused by Plasmodium parasites, poses a significant threat to bird populations worldwide, particularly in vulnerable island ecosystems. Yet, progress in understanding avian malaria transmission dynamics has been hampered by the lack of molecular tools to quantify and sex the transmissible stages of the parasite: the male and ...
A. Berthomieu, I. Rizos, J. W. Bagnoli, S. Gandon, A. M. Talman, A. Rivero   +5 more
wiley   +1 more source

Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria

Frontiers in Immunology, 2019
Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to gametocytes present in human hosts.
Jo-Anne Chan, Damien R. Drew, Linda Reiling, Ashley Lisboa-Pinto, Bismarck Dinko, Colin J. Sutherland, Arlene E. Dent, Kiprotich Chelimo, James W. Kazura, Michelle J. Boyle, James G. Beeson, James G. Beeson, James G. Beeson   +12 more
doaj   +1 more source