Results 61 to 70 of about 18,519 (218)

Defining the signature of deformable and infectious Plasmodium falciparum gametocytes [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background One of the major challenges for malaria elimination is combating the highly efficient spread of the disease. Despite progress in understanding the development of malaria transmission stages, there remain many unanswered questions about how ...
Martijn Huijnen, Teun Bousema, Sanna Rijpma, Wouter Graumans, Matthias Marti, Dario Beraldi, Kathryn crouch, Lisette Meerstein-Kessel, Geert-Jan van Gemert, Deepali Ravel, Armin Passecker, Emmanuel Arinaitwe, Sara Lynn Blanken, Priscilla Ngotho, Stoter Rianne, Daniel Neafsey, Till Voss   +16 more
doaj   +1 more source

Longitudinal impact of asymptomatic malaria/HIV-1 co-infection on Plasmodium falciparum gametocyte transcript expression and transmission to Anopheles mosquitoes

Frontiers in Cellular and Infection Microbiology, 2022
Despite significant developments towards malaria reduction, parasite transmission in the common context of HIV-1 co-infection and treatment for one or both infections has not been fully characterized.
Ashleigh Roberds, Carolyne Kifude, Janet Oyieko, Stephen Ocholla, James Mutunga, James Mutunga, David Oullo, Charles Waga, Zhaozhang Li, Shirley Luckhart, V. Ann Stewart   +10 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

A multiplex assay to detect mosquito species, bloodmeal host source and Plasmodium in malaria vectors using Nanopore amplicon sequencing

Medical and Veterinary Entomology, EarlyView.
Insectary‐reared mosquitoes were simultaneously assessed for species identification, bloodmeal source analysis and Plasmodium detection, using a single multiplexed sequencing run on the MinION sequencing platform. The method was applied to 150 insectary‐reared mosquitoes, representing nine species blood‐fed with five vertebrate hosts and 40 samples for
E. Abby Rogers, Dieunel Derilus, Christopher Sandi, Lisa Reimer, Audrey Lenhart, Lucy Mackenzie Impoinvil   +5 more
wiley   +1 more source

Plasmodium falciparum Gametocyte Enrichment in Peripheral Blood Samples by Magnetic Fractionation: Gametocyte Yields and Possibilities to Reuse Columns [PDF]

The American Journal of Tropical Medicine and Hygiene, 2019
Gametocytes are sexual stage malaria parasites responsible for transmission to mosquitoes. Multiple gametocyte-producing clones may be present in natural infections, but the molecular characterization of gametocytes is challenging. Because of their magnetic properties, gametocyte enrichment can be achieved by magnetic fractionation.
Graumans, Wouter, Andolina, Chiara, Awandu, Shehu S., Grignard, Lynn, Lanke, Kjerstin, Bousema, Teun   +5 more
openaire   +5 more sources

Gametocytes infectiousness to mosquitoes: variable selection using random forests, and zero inflated models [PDF]

, 2010
Malaria control strategies aiming at reducing disease transmission intensity may impact both oocyst intensity and infection prevalence in the mosquito vector.
Genuer, Robin, Morlais, Isabelle, Toussile, Wilson   +2 more
core   +3 more sources

Strong Cross‐Reactivity of Anti–Plasmodium falciparum pLDH Monoclonal Antibodies With Plasmodium malariae pLDH in the Abbott Bioline Malaria Ag P.f/P.f/P.v Rapid Diagnostic Test

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives This study aimed to describe the cross‐reactivity of the Abbott Bioline Malaria Ag P.f/P.f/P.v rapid diagnostic test, designed to detect Plasmodium falciparum and P. vivax, with other Plasmodium species, based on the detection of parasite lactate dehydrogenase enzymes.
Gabriel Montoia, Maria Carmen Arroyo Sanchez, Giselle Lima‐Cooper, Maria de Lourdes Rego Neves Farinas, Juliana Inoue, Silvia Maria Di Santi   +5 more
wiley   +1 more source

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage [PDF]

Malaria Journal, 2015
Plasmodium falciparum sexual development plays a fundamental role in the transmission and spread of malaria. The ability to generate gametocytes can be lost during culture in vitro, often associated with the loss of a subtelomeric region of chromosome 9. Gametocytogenesis starts with erythrocyte invasion by a sexually committed merozoite, but the first
Tiburcio, M, Dixon, MWA, Looker, O, Younis, SY, Tilley, L, Alano, P   +5 more
openaire   +3 more sources

Production of Plasmodium falciparum Gametocytes In Vitro [PDF]

, 2012
Production of gametocytes in vitro is essential for studies of Plasmodium falciparum sexual stages. Here, we describe procedures for the high-yield production and fractionation of P. falciparum gametocytes stages I to V.
Kathryn Shaw, Saliba, Marcelo, Jacobs-Lorena   +1 more
openaire   +2 more sources

Detecting Gametocytes: How Sensitive Is Sensible? [PDF]

The Journal of Infectious Diseases, 2017
Contains fulltext : 190622.pdf (Publisher’s version ) (Open Access)
Meerstein-Kessel, L., Meerstein-Kessel, L., Bousema, T., Stone, W.J.   +3 more
openaire   +3 more sources