Results 1 to 10 of about 511,405 (214)

Dissolution Studies of Physical Mixtures of Indomethacin with Alpha- and Gamma-Cyclodextrins [PDF]

Biomolecules & Biomedicine, 2010
Oral administration of indomethacin has been limited by its poor water solubility. Cyclodextrins have been recognized as potential candidates to overcome the poor solubility of indomethacin through the formation of inclusion complexes.
Edina Vranić, Alija Uzunović
doaj   +2 more sources

Cyclodextrins, Natural Compounds, and Plant Bioactives—A Nutritional Perspective

Biomolecules, 2021
Cyclodextrins (CDs) are a group of cyclic oligosaccharides produced from starch or starch derivatives. They contain six (αCD), seven (βCD), eight (γCD), or more glucopyranose monomers linked via α-1,4-glycosidic bonds.
Svenja Wüpper, Kai Lüersen, Gerald Rimbach   +2 more
doaj   +3 more sources

PPARγ Agonistic Activity of Mimulone and Diplacone Encapsulated in Liposomes and Cyclodextrin Complexes [PDF]

ChemistryOpen
The therapeutic application of flavonoids is limited by their low solubility, bioavailability, and metabolic stability. This study evaluates the peroxisome proliferator‐activated receptor gamma (PPARγ) agonistic activity of two geranylated flavonoids ...
Daniela Nykodýmová, Lenka Molčanová, Jan Kotouček, Josef Mašek, Jakub Treml   +4 more
doaj   +2 more sources

Investigation of Copper Ion Adsorption by Alpha, Beta and Gamma Cyclodextrin by Density Function Method [PDF]

آب و فاضلاب, 2020
Cyclodextrins are categorized into three groups of alpha, beta, and gamma, according to the number of their own glucose units of 6, 7 and 8 units. These ring compounds have two surfaces of hydrophilic and hydrophobic to trap compounds with different ...
Hosein Nourmohamadi, Leily Heidrpoor Saremi, Valeh Aghazadeh   +2 more
doaj   +1 more source

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

Biomedicines, 2021
Irreversible destruction of the hair follicle (HF) in primary cicatricial alopecia and its most common variant, frontal fibrosing alopecia (FFA), results from apoptosis and pathological epithelial-mesenchymal transition (EMT) of epithelial HF stem cells (
Ivan Jozic, Jérémy Chéret, Beatriz Abdo Abujamra, Mariya Miteva, Jennifer Gherardini, Ralf Paus   +5 more
doaj   +1 more source

Fe₃O₄-PAA–(HP-γ-CDs) Biocompatible Ferrimagnetic Nanoparticles for Increasing the Efficacy in Superparamagnetic Hyperthermia

Nanomaterials, 2022
In this paper, we present the obtaining of Fe3O4-PAA–(HP-γ-CDs) ferrimagnetic nanobioconjugates (PAA: polyacrylic acid, HP-γ-CDs: hydroxypropyl gamma-cyclodextrins) in a hybrid core-shell biostructure (core: inorganic Fe3O4 nanoparticles, and shell ...
Costica Caizer, Isabela Simona Caizer, Roxana Racoviceanu, Claudia Geanina Watz, Marius Mioc, Cristina Adriana Dehelean, Tiberiu Bratu, Codruța Soica   +7 more
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High Efficacy on the Death of Breast Cancer Cells Using SPMHT with Magnetite Cyclodextrins Nanobioconjugates

Pharmaceutics, 2023
In this study, we present the experimental results obtained in vitro on the human breast adenocarcinoma cell line (MCF-7) by applying superparamagnetic hyperthermia (SPMHT) using novel Fe3O4-PAA–(HP-γ-CDs) (PAA is polyacrylic acid and HP-γ-CDs is ...
Costica Caizer, Isabela Simona Caizer-Gaitan, Claudia Geanina Watz, Cristina Adriana Dehelean, Tiberiu Bratu, Codruța Soica   +5 more
doaj   +1 more source

Data and meta-analysis for choosing sugammadex or neostigmine for routine reversal of rocuronium block in adult patients

Data in Brief, 2020
This meta-analysis was conducted to define clinical efficacy and side effects (bradycardia and post-operative nausea and vomiting [PONV]) in trials comparing sugammadex with neostigmine or placebo for reversal of rocuronium-induced neuromuscular blockade
William E. Hurford, Mark H. Eckman, Jeffrey A. Welge   +2 more
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Associated-Extraction Efficiency of Six Cyclodextrins on Various Flavonoids in Puerariae Lobatae Radix

Molecules, 2018
Puerariae Lobatae Radix (PLR), a well-known herbal medicine, is the root of Pueraria lobata (Willd.) Ohwi and has been employed for the treatment and prevention of cardiovascular and cerebrovascular diseases.
Tao Feng, Fan Liu, Lili Sun, Hongna Huo, Xiaoliang Ren, Meng Wang   +5 more
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Interaction of Dihydrocitrinone with Native and Chemically Modified Cyclodextrins

Molecules, 2019
Citrinin (CIT) is a nephrotoxic mycotoxin produced by Aspergillus, Penicillium, and Monascus genera. It appears as a contaminant in grains, fruits, and spices.
Zelma Faisal, Sándor Kunsági-Máté, Beáta Lemli, Lajos Szente, Dominik Bergmann, Hans-Ulrich Humpf, Miklós Poór   +6 more
doaj   +1 more source