Results 151 to 160 of about 12,504 (230)

Gamma-Secretase Inhibitor RO4929097 [PDF]

, 2020
openaire   +1 more source

Gamma-secretase inhibitor does not induce cytotoxicity in adult T-cell leukemia cell lines despite NOTCH1 expression. [PDF]

BMC Cancer, 2022
Suzuki S, Hourai S, Uozumi K, Uchida Y, Yoshimitsu M, Miho H, Arima N, Ueno SI, Ishitsuka K.   +8 more
europepmc   +1 more source

A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma. [PDF]

Clin Cancer Res, 2022
Gounder MM, Rosenbaum E, Wu N, Dickson MA, Sheikh TN, D'Angelo SP, Chi P, Keohan ML, Erinjeri JP, Antonescu CR, Agaram N, Hameed MR, Martindale M, Lefkowitz RA, Crago AM, Singer S, Tap WD, Takebe N, Qin LX, Schwartz GK.   +19 more
europepmc   +1 more source

EXTH-82. HIGH NOTCH1 EXPRESSION AND WILD-TYPE P53 DEFINE SYNERGISTIC ACTIVITY BY GAMMA SECRETASE INHIBITORS AND DOXORUBICIN IN GLIOBLASTOMAS [PDF]

, 2017
Chen Zhang, Emmanuel Martínez-Ledesma, Jie Ding, Feng Gao, Shaofang Wu, W.K. Alfred Yung, Dimpy Koul   +6 more
openalex   +1 more source

Androgenic hidradenitis suppurativa onset linked to gamma secretase inhibitor. [PDF]

JAAD Case Rep
Tai H, Hill KT, Parvathaneni A, Islam Z, Cohen SR.   +4 more
europepmc   +1 more source

Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance. [PDF]

Oncologist, 2021
McCaw TR, Inga E, Chen H, Jaskula-Sztul R, Dudeja V, Bibb JA, Ren B, Rose JB.   +7 more
europepmc   +1 more source

Characterization of nectin processing mediated by presenilin‐dependent gamma‐secretase [PDF]

, 2011
Jinsook Kim, Allison Chang, Amanda Dudak, Howard J. Federoff, Seung T. Lim   +4 more
openalex   +1 more source

Presenilin/gamma-secretase regulates neurexin processing at synapses

, 2011
This work was supported by grants from the Junta de Andalucía, Consejería de Innovación, Ciencia y Empresa to FGS (Proyecto de Excelencia P07-CVI-02943) and Ministerio de Ciencia e Innovación of Spain to CAS (SAF2010-20925 and CIBERNED CB06/05/0042).
Gómez Scholl, Francisco Manuel, Servián Morilla, Emilia, Saura, Carlos A.   +2 more
openaire   +2 more sources

Repurposing nirogacestat, a gamma secretase enzyme inhibitor in desmoid tumors. [PDF]

Future Oncol
Tansir G, Rastogi S, Gounder MM.
europepmc   +1 more source

Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia.

Am J Physiol Lung Cell Mol Physiol, 2023
Gwin MS, Alexeyev MF, Geurts AM, Lee JY, Zhou C, Yang XM, Cohen MV, Downey JM, Barrington RA, Spadafora D, Audia JP, Frank DW, Voth S, Pastukh VV, Bell J, Ayers L, Tambe DT, Nelson AR, Balczon R, Lin MT, Stevens T.   +20 more
europepmc   +1 more source