Results 81 to 90 of about 8,778 (220)

Tumor-Infiltrating γδ T Cells Suppress T and Dendritic Cell Function via Mechanisms Controlled by a Unique Toll-like Receptor Signaling Pathway [PDF]

, 2007
Summaryγδ T cells are important contributors to innate immunity against cancer, but their regulatory role in controlling immune responses remains largely unknown.
Guangyong Peng, Helen Y. Wang, Weiyi Peng, Yukiko Kiniwa, Kook Heon Seo, Rong-Fu Wang, Akira, Bauer, Boismenu, Brenner, Bukowski, Choudhary, Constant, Crellin, Curiel, Diefenbach, Dunn, Eberl, Girardi, Groh, Groh, Havran, Hayday, Hayday, Huang, Huang, Jameson, Jameson, Jurk, Kabelitz, Liu, Liyanage, Modlin, Okita, Pasare, Peng, Pennington, Pennington, Qin, Rosenberg, Sakaguchi, Sato, Sato, Shevach, Shin, Sutmuller, Sutmuller, Wan, Wang, Wang, Wang, Wang, Wang, Woo   +53 more
core   +6 more sources

Correction to: Gamma-delta (γδ) T cells: friend or foe in cancer development?

Journal of Translational Medicine, 2018
Following publication of the original article [1], the authors reported that they omitted to state that parts of Fig. 2 were adapted from Van Acker et al. [2] published by Taylor & Francis Ltd (www.tandfonline.com).
Yijing Zhao, Chao Niu, Jiuwei Cui
doaj   +1 more source

Hepatosplenic gammadelta T-cell lymphoma.

World journal of gastroenterology, 2005
To investigate the clinicopathologic characteristics, immunophenotype and TCR gene rearrangements of hepatosplenic T-cell lymphoma in eight Chinese patients.Eight Chinese patients with hepatosplenic gammadelta T-cell lymphomas were studied. Hematoxylin-eosin-stained slides and clinical histories were reviewed.
Shuan-Zeng, Wei, Tong-Hua, Liu, De-Tian, Wang, Jin-Ling, Cao, Yu-Feng, Luo, Zhi-Yong, Liang   +5 more
openaire   +1 more source

The antigen presenting potential of Vγ9Vδ2 T-cells during Plasmodium falciparum blood-stage infection. [PDF]

, 2017
During Plasmodium falciparum infections, erythrocyte-stage parasites inhibit dendritic cell maturation and function; compromising development of effective anti-malarial adaptive immunity. Human Vγ9Vδ2 T-cells can act in vitro as APCs and induce αβ T-cell
Behr, Charlotte, Duluc, Dorothée, Duvignaud, Alexandre, Déchanet-Merville, Julie, Eberl, Matthias, Howard, Jennifer, Loizon, Séverine, Malvy, Denis, Mamani-Matsuda, Maria, Mechain, Matthieu, Mercereau-Puijalon, Odile, Moreau, Jean-Francois, Moser, Bernhard, Troye-Blomberg, Marita, Tyler, Christopher J.   +14 more
core   +2 more sources

Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia

BMC Immunology, 2012
Background Staphylococcus aureus is the major cause of hospital-acquired and community-acquired pneumonia. Host defense to S.aureus infection is largely mediated by the innate immune system.
Cheng Ping, Liu Tao, Zhou Wei-Ying, Zhuang Yuan, Peng Liu-sheng, Zhang Jin-yu, Yin Zhi-Nan, Mao Xu-hu, Guo Gang, Shi Yun, Zou Quan-ming   +10 more
doaj   +1 more source

Benefit of axicabtagene ciloleucel versus chemoimmunotherapy in older patients and/or patients with poor ECOG performance status with relapsed or refractory large B‐cell lymphoma after 2 or more lines of prior therapy

American Journal of Hematology, Volume 99, Issue 5, Page 880-889, May 2024.
Abstract Axicabtagene ciloleucel (axi‐cel) in trials has demonstrated favorable efficacy compared with historical controls after ≥2 lines of therapy for the treatment of relapsed or refractory (R/R) large B cell lymphoma (LBCL). Herein, we compared the real‐world effectiveness of axi‐cel with efficacy and effectiveness of chemoimmunotherapy (CIT) in ...
Matthew A. Lunning, Hai‐lin Wang, Zhen‐Huan Hu, Frederick L. Locke, Tanya Siddiqi, Caron A. Jacobson, Sairah Ahmed, David B. Miklos, Yi Lin, Brian T. Hill, Armin Ghobadi, Sattva S. Neelapu, Jason Westin, Christopher Dieyi, Polly Field, Harry Miao, Shilpa A. Shahani, Anik Patel, Clare Spooner, Christine Fu, David Muramoto, Hairong Xu, Marcelo C. Pasquini   +22 more
wiley   +1 more source

IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]

, 2018
Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K., Evans, Tom J., Mitchell, Tim J., Ritchie, Neil D., Ritchie, Ryan   +4 more
core   +3 more sources

Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance

Microbiome, 2023
Background Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition.
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, Chantal Kuhn, Howard L. Weiner   +16 more
doaj   +1 more source

TCR signal strength controls thymic differentiation of discrete proinflammatory gamma delta T cell subsets [PDF]

, 2016
The mouse thymus produces discrete gd T cell subsets that make either interferon-g (IFN-g) or interleukin 17 (IL-17), but the role of the T cell antigen receptor (TCR) in this developmental process remains controversial. Here we show that Cd3g+/− Cd3d+/−
Ana Pamplona, Ana R Grosso, B Silva-Santos, B Silva-Santos, Bruno Silva-Santos, BS Carvalho, BS Sheridan, CE Sutton, CL Roark, DA Zapata, Daniel J Pennington, E Fernández-Malavé, Edgar Fernández-Malavé, F Coffey, F Petermann, G Turchinovich, GM Siegers, HS Azzam, I Prinz, JC Ribot, JC Ribot, JD Haas, JD Haas, José R Regueiro, JS Cho, Julie C Ribot, K Narayan, KD Jensen, L Romani, M Ciofani, M Rei, M Wencker, MC D'Ombrain, MC Haks, MC Haks, ME Ritchie, Miguel Muñoz-Ruiz, MP Seiler, N Malhotra, N Schmolka, N Schmolka, Natacha Gonçalves-Sousa, P Jagannathan, P Liehl, P Wu, RL O'Brien, S Pantelyushin, SG Park, SM Hayes, SM Hayes, SM Hayes, SM Hayes, T Shichita, T Wang, VP Dave, W Huber, X Gu, Y Cai, Y Cai, Y Gao, Y Kannan   +60 more
core   +2 more sources

Aumento da produção de IL-4: resposta ao Mycobacterium tuberculosis virulento em doentes com tuberculose em estádio avançado.

Acta Médica Portuguesa, 2005
The study was designed to compare immune responses to Mycobacterium tuberculosis bacilli and antigens in healthy Portuguese subjects and pulmonary tuberculosis patients (TB), and to correlate immune status with clinical severity of tuberculosis disease ...
Diane J Ordway, Marta S Martins, Leonor M Costa, Mónica S Freire, Maria J Arroz, Hazel M Dockrell, Fernando A Ventura   +6 more
doaj   +1 more source