Results 51 to 60 of about 44,210 (231)
Selection, counterselection, and conditional gene expression for genetic biocontrol of insects
Selection, counterselection, and conditional expression can be used for sex separation. Selection (S) and counterselection (CS) genes are linked to the sex chromosomes (e.g., the X and Y chromosomes) to confer sex‐specific selection or counterselection based on the presence or absence of the S or CS genes.
Melanie Hempel, Zhijian Tu
wiley +1 more source
Jane Huang,1 Kazuaki Kadonosono,2 Eiichi Uchio1 1Department of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, 2Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan Purpose: The most common external ocular
Huang J, Kadonosono K, Uchio E
doaj
Valganciclovir—Ganciclovir Use and Systematic Therapeutic Drug Monitoring. An Invitation to Antiviral Stewardship [PDF]
Alicia Galar +11 more
openalex +1 more source
Mouse genome engineering uncovers 18 genes dispensable for male reproduction
Abstract Background Male infertility is an intricate multifactorial disease involving the interplay between genetic and environmental factors. Genetic anomalies account for more than 15% of all male infertility cases; however, diagnosing them exhibits enormous challenges due to variable symptomatic presentations and limited knowledge of gene functions.
Hsin‐Yi Chang +7 more
wiley +1 more source
Background The purpose of this study is to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections to treat cytomegalovirus retinitis in patients without human immunodeficiency virus (HIV) infection.
Zhuyun Qian +3 more
doaj +1 more source
The Role of Early Vitrectomy in the Healing of Retinal Lesions in Progressive Outer Retinal Necrosis
Purpose. To report on the efficacy of early pars plana vitrectomy (PPV), silicone oil (SO) tamponade, and intravitreal ganciclovir injection in the treatment of a case with progressive outer retinal necrosis (PORN). Case Presentation.
Hamid Riazi-Esfahani +6 more
doaj +1 more source
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena +1 more
core +4 more sources
Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model. [PDF]
Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo.
Chang, Deching +13 more
core +2 more sources
BACKGROUND Cytomegalovirus (CMV) infection is common in individuals with inflammatory bowel disease (IBD) and is responsible for relapse, increased severity, and poor outcome if left untreated. Ganciclovir is the mainstay of treatment but data regarding
Iftikhar Ahmed +4 more
doaj +1 more source
CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL +4 more
core +1 more source

