Results 61 to 70 of about 40,022 (185)

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca, Cardi, Veronica, DE CURTIS, Mario, Fabio, Natale, Gaeta, Aurelia, Giuseppina, Liuzzi, Paola, Villani   +6 more
core   +2 more sources

A Case of Fulminant Immune‐Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai, Takayuki Sumiyoshi, Hiroki Kitamoto, Yuki Teramoto, Yuta Mine, Jin Kono, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

Maribavir for Cytomegalovirus Infection in High‐Risk Kidney Transplant Recipients: A Case Series

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Background Cytomegalovirus (CMV) infection remains a common complication after kidney transplantation, particularly among high‐risk donor‐seropositive/recipient‐seronegative (D+/R−) recipients. Valganciclovir is the standard first‐line therapy; however, its use may be limited by hematological toxicity or impaired graft function. Maribavir is a
Daiji Takamoto, Yu Shimada, Yuri Hasegawa, Takeaki Noguchi, Takashi Kawahara, Junichi Teranishi, Kazuhide Makiyama   +6 more
wiley   +1 more source

Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure

CPT: Pharmacometrics & Systems Pharmacology, 2019
Intravenous ganciclovir and oral valganciclovir are effective in the prevention and treatment of pediatric cytomegalovirus (CMV) infection but various dosing regimens are used in medical practice.
Karin Jorga, Bruno Reigner, Clarisse Chavanne, Giuseppe Alvaro, Nicolas Frey   +4 more
doaj   +1 more source

Alemtuzumab induction and tacrolimus monotherapy in pancreas transplantation: One- and two-year outcomes [PDF]

, 2006
BACKGROUND. Alemtuzumab (Campath-1H) induction with tacrolimus monotherapy has been shown to provide effective immunosuppression for kidney, liver, lung, and small bowel transplantation.
Abu-Elmagd, Akhtar Khan, Amadeo Marcos, Amit Basu, Calne, Ciano, Deanna Blisard, Flechner, Gruessner, Hale, Henkie P. Tan, John J. Fung, Kaufmann, Kirk, Knechtle, Knechtle, Kusum Tom, Marcos, Marcos, McCurry, Ngoc L. Thai, Ron Shapiro, Shapiro, Shapiro, Starzl, Starzl, Starzl, Starzl, Stuart, Thai, Thomas E. Starzl, Tryphonopoulos, Tzakis, Watson   +33 more
core   +1 more source

Laryngeal Transplantation in Cancer Patients: Evaluation of Surgical Outcomes and Functional Recovery

MedComm, Volume 7, Issue 5, May 2026.
Our pilot clinical study in laryngeal transplantation achieved divergent outcomes: two cases maintained functional speech/swallowing with around 2 year graft survival and have been ongoing, while two succumbed to sepsis (10mo) and hemorrhagic recurrence (11mo).
Zheng Jiang, Mailudan Ainiwaer, Pengwei Zhao, Yansheng Hu, Xin Yang, Yu Xiong, Bin Zeng, Longhao Wang, Jun Liu, Fei Chen   +9 more
wiley   +1 more source

In Vitro Treatment with Ganciclovir Restores the Functionality of Exhausted T Cells from Cancer Patients

International Journal of Gerontology, 2013
Background: Human cytomegalovirus (CMV) is a lifelong, often asymptomatic infection, with the virus maintained in latently infected myeloid cells. Patients receiving chemotherapy for cancer are at high risk of reactivation of latent CMV, which may ...
Chia-Ming Chang, Chien-Liang Wu, I-Hsuan Chen, Kate Hsu, Hsin-Tsung Ho, I-Pin Chuang, Yen-Ta Lu   +6 more
doaj   +1 more source

Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]

, 2016
Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P, Byrne, James A, Chang, Katherine M, Hermann, Kip J, Lee, Patrick C, Lipshutz, Gerald S, Schoenberg, Benjamen E, Truong, Brian, Vega-Crespo, Agustin, Wu, Lily   +9 more
core   +3 more sources

Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model. [PDF]

, 2020
Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo.
Chang, Deching, Chang, Hao-Fang, Chen, Bing-Mao, Chen, Shih-Han, Chen, Thomas C, Collins, Sara, Kasahara, Noriyuki, Lin, Sheng-Che, Lu, Yin-Che, Sun, Jui-Ming, Tai, Chien-Kuo, Wang, Hsin-Ell, Wang, Weijun, Wu, Shu-Fen   +13 more
core   +2 more sources

Ferrocene‐Based Sensors for Green Analytical Applications in Environmental, Biomedical, Industrial, and Food Monitoring

ChemistryOpen, Volume 15, Issue 5, May 2026.
Ferrocene derivatives represent a transformative class of molecular sensors, combining exceptional electrochemical stability with tunable redox characteristics that enable precise detection across diverse analytical challenges in environmental, medical, and industrial applications.
Ala'a Al‐Akhras, Asma Ghazzy, Zainab Zakaraya, Ala'a S. Shraim, Obada A. Sibai, Laila Alsabbagh, Deeb Taher   +6 more
wiley   +1 more source