Results 71 to 80 of about 28,258 (196)

Tumors treated with lentiviral vectors and ganciclovir show complete remission on MRI.

, 2013
Representative three-dimensional MRI (T2 RARE). (A,F,K,P) Lentiviral LCMV-GP vectors with ganciclovir treatment. (B,G,L,Q) Lentiviral VSV-G vectors with ganciclovir treatment. (C,H,M,R) Lentiviral LCMV-GP vectors without ganciclovir treatment.
Rolf Bjerkvig (68682), Philipp Euskirchen (371673), Kai Ove Skaftnesmo (148358), Peter C. Huszthy (325266), Hrvoje Miletic (211715), Dorothee von Laer (307452), Oleg Tsinkalovsky (371670), Tsanan Giroglou (371669)   +7 more
core   +1 more source

Effect of a Histone Demethylase Inhibitor on Equine Herpesvirus-1 Activity In Vitro

Frontiers in Veterinary Science, 2018
Equine herpesvirus type 1 (EHV-1) is a ubiquitous and highly contagious pathogen that causes a range of disease severities with outbreaks of notable economic impact.
Rebecca L. Tallmadge, Emilija Žygelytė, Gerlinde R. Van de Walle, Thomas M. Kristie, M. Julia B. Felippe   +4 more
doaj   +1 more source

Secondary Pulmonary Alveolar Proteinosis Associated With Ruxolitinib After Bone‐Marrow Transplantation: A Case With Transient Improvement Following Drug Discontinuation

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Secondary pulmonary alveolar proteinosis (PAP) may occur in patients receiving ruxolitinib for steroid‐refractory GVHD after bone marrow transplantation. In this case, a 47‐year‐old woman developed respiratory failure 8 months after commencing ruxolitinib therapy, and initial radiological and clinical improvements occurred after drug withdrawal, prior ...
Taiki Yanagi, Maki Asami‐Noyama, Kaoru Yamamoto, Yoshinobu Hoshii, Yasushi Ichiyama, Masatoshi Okimura, Tetsuya Fujii, Junki Suizu, Misa Harada, Keita Murakawa, Kazuki Hamada, Toshiaki Utsunomiya, Yoriyuki Murata, Keiji Oishi, Nobutaka Edakuni, Tomoyuki Kakugawa, Tsunahiko Hirano, Kazuto Matsunaga   +17 more
wiley   +1 more source

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

, 2002
Nonmyeloablative conditioning is increasingly used for transplantation in a wide range of diseases, but little is known about its impact on the incidence of infections and immune reconstitution.
Mahendra, P, Marshall, T, O'Gorman, P, Osman, H., Chakraverty, R, Hale, G., Osman, H, Peggs, K., O'Gorman, P., Mahendra, Premini, Mackinnon, S, Fegan, Christopher, Chopra, Ravinder, Linch, DC, Goldstone, A.H., Chopra, R, Waldmann, H., Milligan, D.W., Chakrabarti, Suparno, Hale, G, Chakrabarti, S., Marshall, T., Chakrabarti, S, Peggs, K, Chakraverty, Ronjon, Chopra, R., Waldmann, H, Kottaridis, P.D., Craddock, C., Milligan, DW, Mackinnon, S., Chakraverty, R., Kottaridis, PD, Yong, K., Kottaridis, P, Milligan, Donald, Mahendra, P., Craddock, Charles; id_orcid, Craddock, C, Yong, K, Goldstone, AH, Waldmann, Herman, Fegan, CD, Fegan, C.D., Linch, D.C.   +44 more
core   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, Volume 59, Issue 6, June 2026.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Determination of ganciclovir in lung transplant recipients [PDF]

Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Filip Hrach Supervisor: prof. Ing. Barbora Szotáková, Ph.D. Consultant: doc. Ing. Eva Klapková, Ph.D.
Hrach, Filip
core   +1 more source

Severe Occupational Hypersensitivity Pneumonitis: A Case Series of Four Patients Requiring Lung Transplantation

American Journal of Industrial Medicine, Volume 69, Issue 5, Page 323-334, May 2026.
ABSTRACT Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease triggered by repeated inhalation of organic or chemical antigens. Occupational exposures account for approximately 19% of all cases. Early diagnosis, identification of the responsible antigen(s), and immediate avoidance of exposure are crucial to prevent ...
Ludwig Frei‐Stuber, Judith Mohren, Ester Mau, Bernhard Werner, Rudolf A. Hatz, Jürgen Barton, Dennis Nowak   +6 more
wiley   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang, Bingjie Wang, Yujun Dong, Qingya Wang, Qian Wang, Jialin Zhu, Qingyun Wang, Na Han, Yuan Li   +8 more
wiley   +1 more source

Does Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait?

Advances in Virology, 2011
The resistance of cytomegalovirus (CMV) to ganciclovir or valganciclovir is a factor in therapeutic failure and disease progression. CMV strains resistant to ganciclovir or valganciclovir have been associated with specific mutations in the UL97 and UL54 ...
Nada Madi, Widad Al-Nakib, Alexander Pacsa   +2 more
doaj   +1 more source

B‐Lymphoblastic Leukemia With Isolated Central Nervous System Relapse Mimicking a Vestibular Schwannoma

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The central nervous system (CNS) is the most common site of extramedullary relapse in acute lymphoblastic leukemia (ALL). However, the diagnosis may be challenging due to its protean manifestations. A 64‐year‐old male reported right‐sided hearing loss with intermittent bilateral occipitotemporal headaches during a clinic follow‐up for Ph + B ...
Jun Yen Ng, Shivendra T. Lalloo, Samuel Milliken, Mark N. Polizzotto   +3 more
wiley   +1 more source