Role of Membrane GM1 on Early Neuronal Membrane Actions of Aβ During Onset of Alzheimer\u27s Disease [PDF]
, 2017 The ability of beta-amyloid peptide (Aβ) to disrupt the plasma membrane through formation of pores and membrane breakage has been previously described. However, the molecular determinants for these effects are largely unknown.
Aguayo, Luis G. +3 more
core +1 more source
Neural Metabolic Networks: Key Elements of Healthy Brain Function
Journal of Neurochemistry, Volume 169, Issue 6, June 2025.This review originated from the Fourth International Society for Neurochemistry (ISN) and Journal of Neurochemistry (JNC) Flagship School (2022). Here, we describe how the specific bioenergetic profiles and metabolic exchanges between brain cells enable and gate synaptic function and behavior. Then, based on this analysis, we discuss the potential role
Nimrod Madrer +20 more
wiley +1 more source
Application of electrospray mass spectrometry to the analysis of lipids : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Food Technology at Massey University [PDF]
, 2000 This work investigated the application of electrospray mass spectrometry (MS) to the elucidation of lipid structure, especially related to milkfat. This was the first time that the instrument in our laboratory had been used for this purpose.
Norris, Carmen
core
Diagnosis and Management of Multifocal Motor Neuropathy in the United Kingdom: A Multicentre Survey
Journal of the Peripheral Nervous System, Volume 30, Issue 2, June 2025.ABSTRACT Background We conducted a survey to determine the current diagnosis and treatment of multifocal motor neuropathy (MMN) in the United Kingdom. Methods Demographic, diagnostic and treatment data were collected at nine UK neuroscience centres. Results Ninety‐five subjects were included. Mean age at diagnosis was 49.9 years (SD: 11.4).
Yusuf A. Rajabally +18 more
wiley +1 more source
Association of NGF receptors with membrane rafts in PC12 cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 2001 Nerve Growth Factor (NGF) signal transduction is involved in the survival, differentiation and maintenance of neurons through the receptors TrkA and p75NTR. These receptors activate downstream protein kinase cascades that regulate cell survival.
Clements, Shona Marie
core
Induction of neuron-like tubes and liposome networks by cooperative effect of gangliosides and phospholipids [PDF]
Although there is a rather large abundance of gangliosides in neurons, their functional role is still unclear. We focused on a physicochemical role of gangliosides in the formation of tubular structures, such as axons or dendrites in neurons.
Akiyoshi, Kazunari +4 more
core +1 more source
The role of complex gangliosides in glial cell biology [PDF]
, 2008 Gangliosides are a family of sialic acid-containing glycosphingolipids that are enriched in the nervous system. They are located in the outer leaflet of the plasma membrane within lipid rafts and are thought to be involved in numerous cellular events ...
Silajdzic, Edina
core +1 more source
Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A [PDF]
, 2008 Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Baskaran Thyagarajan +5 more
core +1 more source
Marked efficacy of Rituximab in multifocal motor neuropathy associated with chronic lymphocytic leukemia [PDF]
, 2016 The authors describe a patient who presented a multifocal motor neuropathy (MMN) associated with a high anti-ganglioside antibody (anti-GM1 and anti-GD1) titer at the clinical onset of a B-cell chronic lymphocytic leukemia (B-CLL). Immunomodulation (IVIg
Antonella Di, Pasquale +6 more
core
Editorial: Glioma invasion: mechanism, modulation and future possibilities [PDF]
, 2003 Amberger-Murphy, Verena
core +1 more source