Results 91 to 100 of about 5,135,710 (246)

Antiangiogenic compounds: well-established drugs versus emerging natural molecules [PDF]

, 2018
Angiogenesis is the natural and physiologic process of growing blood vessels from pre-existing ones. Pathological angiogenesis occurs when the precise balance of all the molecular pathways that regulate angiogenesis is disrupted, and this process is a ...
Abreu, Rui M.V., Barreiro, M.F., Dias, Madalena M., Ferreira, Isabel C.F.R., Ribeiro, Andreia   +4 more
core   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source

Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation

Cell Proliferation, Volume 58, Issue 9, September 2025.
Sirt3 deacetylated SOD2 via K68 to orchestrate P.g.‐impaired cementogenesis. Reestablishment of the Sirt3/SOD2 axis by honokiol reduced SOD2 acetylation and facilitated cementogenesis. ABSTRACT The keystone pathogen Porphyromonas gingivalis (P.g.) is responsible for cementum resorption in periodontitis; however, the mechanism involved in it remains ...
Xin Huang, Huiqing Gou, Jirong Xie, Yonglin Guo, Yifei Deng, Yan Xu, Zhengguo Cao   +6 more
wiley   +1 more source

Optimum Condition of Ecologic Feed Fermentation by Pleurotus ostreatus Using Soybean Curd Residue as Raw Materials [PDF]

, 2011
A novel approach by utilizing soybean curd residue, to produce polysaccharide from the edible mushroom Pleurotus ostreatus in solid-state culture, was developed. Firstly, the significant effect of fermented conditions on P.
Li Yiting, Shi Min, Wang Yuepeng, Yang Yingnan, Zhang Zhenya, 史 敏, 張 振亜, 楊 英男   +7 more
core   +1 more source

Jianpi‐Huogu Prescription Repairs Nontraumatic Osteonecrosis of the Femoral Head by Inhibiting NAMPT/STK11/HMGCR/ACAT1 Axis‐Mediated Lipid Production

Journal of Cellular and Molecular Medicine, Volume 29, Issue 18, September 2025.
ABSTRACT Jianpi‐Huogu Prescription (JHP), integrating the classic Chinese herbal formulas Linggui‐Zhugan Decoction and Si‐Wu Decoction, has shown clinical efficacy in treating early nontraumatic osteonecrosis of the femoral head (NONFH). In this study, 299 chemical constituents of JHP were identified using ultra‐performance liquid chromatography ...
Tao Li, Zhaochen Ma, Shuangrong Gao, Chu Zhang, Yan Jia, Huang Feng, Na Lin, Weiheng Chen, Yanqiong Zhang   +8 more
wiley   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, Volume 12, Issue 31, August 21, 2025.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Ganoderma Sinense Soluble Dietary Fiber Alleviates Nonalcoholic Fatty Liver Disease by Regulating Liver Metabolism

eFood, Volume 6, Issue 4, August 2025.
This study evaluated the effect of soluble dietary fiber from Ganoderma sinense on nonalcoholic fatty liver disease (NAFLD) by establishing in vitro cell and in vivo mouse models. Ganoderma sinense soluble dietary fiber (GSSDF) alleviates nonalcoholic fatty liver disease by regulating lipid metabolism and reducing oxidative stress.
Ping Shao, Ying Yang, Zhenhao Li, Jihong Yang, Guoliang Zhang, Jianhua Zhang, Mengyao Wang   +6 more
wiley   +1 more source

Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus [PDF]

, 2016
Relative concentration of metabolites identified in Vibrio parahaemolyticus ATCC17802. (XLSX 113 kb)
Bo Feng, Weijia Zhang, Yingjie Pan, Yong Zhao, Zhuoran Guo   +4 more
core   +3 more sources

MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

Exploration, Volume 5, Issue 4, August 2025.
Our findings suggest that miR‐29a/b is a critical regulator of CD8+ T cells, possibly via the Ifng‐JAK‐STAT signal in IBD patients and the upregulation of miR‐29a/b relieves the development of significant inflammation in the colon of DSS‐induced colitis‐affected mice.
Yingying Lin, Yuqi Wang, Yuning Zhang, Yao Lu, Juan Chen, Yongting Luo, Jian He, Qingfeng Luo, Heng Quan, Weiru Yu, Yujia Luo, Peng Xue, Yi Xue, Xiaoya Lin, Rui Ding, Lining Chen, Yiran Wang, Zenghui Xia, Liang Zhao, Hao Zhang, Ran Wang, Qingyu Wang, Xifan Wang, Jiaqi Su, Fazheng Ren, Cong Lv, Yixuan Li, Huiyuan Guo   +27 more
wiley   +1 more source

Anticancer Activity of Ganoderic Acid DM: Current Status and Future Perspective

Journal of Clinical & Cellular Immunology, 2017
Ganoderma lucidum is a mushroom that has a long history of medicinal use in the Far East countries as this mushroom is revered for its supposed miracle cures and life improving properties. Recently, this mushroom has come under scientific scrutiny to examine the possibility of finding biologically active compounds that may have an impact on human ...
Bryant, John Matthew, Bouchard, Mollie, Haque, Azizul   +2 more
openaire   +2 more sources