Results 71 to 80 of about 9,792 (169)

Phytofabricated Silver Nanoparticles From Vaccinium arctostaphylos L.: Anticancer Activity Against Breast Cancer Cells via Apoptosis Induction and Growth Suppression

Food Science &Nutrition, Volume 13, Issue 11, November 2025.
This study demonstrates that phytofabricated silver nanoparticles (VACAgNPs) from Vaccinium arctostaphylos L. exhibit significant anticancer activity against breast cancer cells, inducing apoptosis and suppressing growth in both hormone‐responsive (MCF‐7) and triple‐negative (4T1, MDA‐MB‐231) subtypes. The nanoparticles enhanced reactive oxygen species
Nazila Soleimani, Zahra Keshtmand, Nader Goodarzi, Mohsen Akbaribazm   +3 more
wiley   +1 more source

Sustainable Natural Product Glycosylation: A Critical Evaluation of Biocatalytic and Chemical Approaches

ChemSusChem, Volume 18, Issue 20, October 23, 2025.
Developing a process to produce glycosylated natural products involves many decisions, and given the current climate crisis, the environmental impact of the various processes must be a major consideration. This review provides an overview of the various processes and a framework for which metrics should be quantified to select processes that are both ...
Felipe Mejia‐Otalvaro, Brianna Marie Lax, Onur Kırtel, Ditte Hededam Welner   +3 more
wiley   +1 more source

Functional Foods Enriched With Bioactive Compounds: Therapeutic Potential and Technological Innovations

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Functional foods enriched with bioactive compounds such as polyphenols, carotenoids, omega‐3 fatty acids, and probiotics provide therapeutic benefits through antioxidant, anti‐inflammatory, and gut‐modulating mechanisms. Advances in biotechnology and AI have improved screening, formulation, and delivery of these compounds in diverse food matrices ...
Zargull Arshad, Shafa Shahid, Ammarah Hasnain, Esha Yaseen, Mehdi Rahimi   +4 more
wiley   +1 more source

Ganoderic acid A alleviate psoriasis by inhibiting GSDMD-mediated pyroptosis

Tissue and Cell
Psoriasis is a chronic inflammatory dermatological condition characterized by the infiltration of inflammatory cells into the dermal layer. This study aimed to elucidate the anti-inflammatory properties and underlying molecular mechanisms of Ganoderic acid A in the treatment of psoriasis.A psoriasis model was induced in mice using IMQ to evaluate the ...
Chenggen Xiao, Junchen Chen, Xingchen Zhou, Hong Liu   +3 more
openaire   +2 more sources

MOESM1 of Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum

, 2019
Additional file 1: Figure S1. (A) The expression vector pJW-EXP-FPS. (B) Identification and characterization of the FPF gene-overexpressing strain. Amplification pattern of genomic PCR obtained with primers for the fusion of the gpd promoter and FPS gene fragment from different strains.
Fei, Yu, Li, Na, Zhang, De-Huai, Xu, Jun-Wei   +3 more
openaire   +1 more source

Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study

Tumor Biology, 2016
Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration in the RTK signaling modulates the downstream signaling pathways that results in cancer.
Balraj Singh, Gill, , Navgeet, Sanjeev, Kumar   +2 more
openaire   +2 more sources

Ethanolic Extract of Ganoderma mexicanum Pat. Mycelium: A Source of Bioactive Compounds with Antiproliferative Activity and Potential PPAR-γ Natural Ligands

Pharmaceuticals
Background/Objective: Ganoderma spp. have long been studied for their bioactive pharmacological properties, and their biomass and extracts have been obtained from various sources.
Lucia T. Angulo-Sanchez, Max Vidal-Gutiérrez, Heriberto Torres-Moreno, Martín Esqueda, Aldo Gutiérrez, Georgina Vargas, Juan Luis Monribot-Villanueva, José A. Guerrero-Analco, César Muñoz-Bacasehua, Ramón Enrique Robles-Zepeda   +9 more
doaj   +1 more source

Anticancer Activity of Ganoderic Acid DM: Current Status and Future Perspective

Journal of Clinical & Cellular Immunology, 2017
Ganoderma lucidum is a mushroom that has a long history of medicinal use in the Far East countries as this mushroom is revered for its supposed miracle cures and life improving properties. Recently, this mushroom has come under scientific scrutiny to examine the possibility of finding biologically active compounds that may have an impact on human ...
Bryant, John Matthew, Bouchard, Mollie, Haque, Azizul   +2 more
openaire   +2 more sources

Enhanced production of individual ganoderic acids by integrating Vitreoscilla haemoglobin expression and calcium ion induction in liquid static cultures of Ganoderma lingzhi

Microbial Biotechnology, 2019
Summary Ganoderic acids produced by Ganoderma exhibit anticancer and antimetastatic activities. A novel approach by combining Vitreoscilla haemoglobin (VHb) expression and calcium ion induction was developed to enhance ganoderic acid (GA) production in ...
Jun‐Wei Xu, Tong‐Hui Yue, Xuya Yu, Peng Zhao, Tao Li, Na Li   +5 more
doaj   +1 more source

Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma

Drug Delivery, 2019
This work evaluates nano-lipid carrier of ganoderic acid (GA) and molecular docking on various cancer signaling pathways, an attempt to improve the hepatic condition associated with hepatic carcinoma (HCC) induced by diethyl-nitrosamine (DEN) in Wistar ...
Mahfoozur Rahman, Shareefa Abdullah Al-Ghamdi, Khalid S Alharbi, Sarwar Beg, Kalicharan Sharma, Firoz Anwar, Fahad A Al-Abbasi, Vikas Kumar   +7 more
doaj   +1 more source