Results 71 to 80 of about 10,080 (200)
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Improved ganoderic acids production in Ganoderma lucidum by wood decaying components [PDF]
Scientific Reports, 2017 AbstractGanoderma lucidumis a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs). GAs are largely produced in the mushroom primordium and fruiting body but much less in mycelium stage. However, little is known on the underlying regulatory mechanism.
Yanru Hu +7 more
openaire +2 more sources
, 2018 Bacillus subtilis ATCC (American type culture collection) 6633 was found to biotransform ganoderic acid A (GAA), which is a major lanostane triterpenoid from the medicinal fungus Ganoderma lucidum.
Kun-Yuan Wu +4 more
core +1 more source
Microbial Biotechnology, Volume 19, Issue 1, January 2026.This study reveals that Lactobacillus salivarius Li01 alleviates acute pancreatitis by increasing gut Paramuribaculum. This modulation of the microbiota and its steroid hormone metabolites suppresses the pancreatic TNF signaling pathway, uncovering a protective ‘gut‐metabolism‐immunity’ axis.
Jiamin Duan +5 more
wiley +1 more source
Ganoderic acid and its derivatives as cholesterol synthesis inhibitors.
Chemical and Pharmaceutical Bulletin, 1989 Oxygenated lanosterol derivatives, which were isolated from Ganoderma lucidum (Polyporaceae) or their derivatives obtained by chemical conversion, were tested for their effect on cholesterol biosynthesis from 24,25-dihydrolanosterol by rat hepatic subcellular 10,000 x g supernatant fraction.
KOMODA, Yasuo +3 more
openaire +3 more sources
Journal of Phytopathology, Volume 174, Issue 1, January/February 2026.ABSTRACT This study aimed to evaluate the potential of the mycelial growth filtrate (MGF) from Ganoderma lucidum in providing systemic protection to tomato plants against Septoria lycopersici‐induced leaf spot and inhibiting the production of reproductive structures by the phytopathogen. In greenhouse experiments, foliar application of MGF at 40% (v/v)
Mycheli P. Cruz +3 more
wiley +1 more source
Effect of aspirin concentration on the accumulation of ganoderic acids and fungal biomass.
, 2013 Fungal mycelium was cultured on PDA for 4 days and then incubated with 0.5–8 mM aspirin for additional 1 day. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs) (C)
Hui-Chuan Hsieh (289703) +7 more
core +1 more source
Interaction of ganoderic acid on HIV related target: molecular docking studies [PDF]
Bioinformation, 2011 Trouver le remède ultime contre le VIH reste une tâche difficile depuis des décennies. Divers composés actifs ont été testés contre divers composants du virus dans le but d'arrêter le développement du virus chez l'hôte infecté. L'idée de trouver un remède à partir de composés naturels pharmacologiquement actifs connus est intrigante et pratique.
Rahmad Akbar, Wai Keat Yam
openaire +2 more sources
Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review
BioMed Research International, Volume 2026, Issue 1, 2026.All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh +3 more
wiley +1 more source
Synthesis of ganoderic acid analogues to investigate their activity as anti-prostate cancer agents [PDF]
, 2019 Cancers are one of the leading causes of premature human death globally. Prostate cancer is the second most common cancer in the world; chemoprevention can help decrease the proportion of fatal cases and prevent recurrence of the cancer.
Al-Obaidi, Mohammed
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