Results 51 to 60 of about 10,827 (210)

A novel approach to enhancing ganoderic acid production by Ganoderma lucidum using apoptosis induction. [PDF]

PLoS ONE, 2013
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and enhancing GA production are critical to using G.
Bang-Jau You, Miin-Huey Lee, Ni Tien, Meng-Shiou Lee, Hui-Chuan Hsieh, Lin-Hsien Tseng, Yu-Lin Chung, Hong-Zin Lee   +7 more
doaj   +1 more source

The Triterpenoid High-Performance Liquid Chromatography Analytical Profiles of the Mycelia of Ganoderma lucidum (lingzhi)

Microbiology Research, 2023
(1) Background: Ganoderic acids (GAs) are specific triterpenes of Ganoderma lucidum. The HPLC fingerprint profile of GAs of the fruiting body is well known, but their mycelial fingerprinting remains unclear.
Deng-Hai Chen, Jian-Yuan Wang, Mon-Tarng Chen, Yen-Chun Liu, Kuang-Dee Chen   +4 more
doaj   +1 more source

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes. [PDF]

, 2014
Breast cancer metastasis is one of the major reasons for the high morbidity and mortality of breast cancer patients. In spite of surgical interventions, chemotherapy, radiation therapy and targeted therapy, some patients are considering alternative ...
Jedinak, Andrej, Jiang, Jiahua, Loganathan, Jagadish, Nakshatri, Harikrishna, Sandusky, George E., Sliva, Daniel, Smith, Amanda, Thyagarajan-Sahu, Anita   +7 more
core   +3 more sources

Improved ganoderic acids production in Ganoderma lucidum by wood decaying components [PDF]

Scientific Reports, 2017
AbstractGanoderma lucidumis a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs). GAs are largely produced in the mushroom primordium and fruiting body but much less in mycelium stage. However, little is known on the underlying regulatory mechanism.
Yanru Hu, Shakeel Ahmed, Jiawei Li, Biaobiao Luo, Zengyan Gao, Qiyun Zhang, Xiaohua Li, Xuebo Hu   +7 more
openaire   +2 more sources

Ganoderic Acid TR, a New Lanostanoid with 5α-Reductase Inhibitory Activity from the Fruiting Body of

Natural Product Communications, 2006
By means of 5α-reductase inhibitory activity-guided fractionation, a new lanostanoid, 15α-hydroxy-3-oxolanosta- 7, 9(11), 24(E)-trien-26-oic acid, named as ganoderic acid TR, was isolated from the ethanol extract of the fruiting bodies of Ganoderma ...
Jie Liu, Kuniyoshi Shimizu, Ryuichiro Kondo   +2 more
doaj   +1 more source

Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer’s Disease by Regulating DNA Methylation in Rodents

Frontiers in Pharmacology, 2019
Age-related changes in methylation are involved in the occurrence and development of tumors, autoimmune disease, and nervous system disorders, including Alzheimer’s disease (AD), in elderly individuals; hence, modulation of these methylation changes may ...
Guoxiao Lai, Guoxiao Lai, Yinrui Guo, Diling Chen, Xiaocui Tang, Ou Shuai, Tianqiao Yong, Dongdong Wang, Chun Xiao, Gailian Zhou, Yizhen Xie, Burton B. Yang, Burton B. Yang, Qingping Wu   +13 more
doaj   +1 more source

Effect of Pd-Sensitization on Poisonous Chlorine Gas Detection Ability of TiO₂: Green Synthesis and Low-Temperature Operation

Sensors, 2022
Ganoderma lucidum mushroom-mediated green synthesis of nanocrystalline titanium dioxide (TiO2) is explored via a low-temperature (≤70 °C) wet chemical method. The role of Ganoderma lucidum mushroom extract in the reaction is to release the ganoderic acid
Satish Ekar, Umesh T. Nakate, Yogesh B. Khollam, Shoyebmohamad F. Shaikh, Rajaram S. Mane, Abu ul Hassan S. Rana, Marimuthu Palaniswami   +6 more
doaj   +1 more source

Tissue invasion and metastasis: molecular, biological and clinical perspectives [PDF]

, 2015
Cancer is a key health issue across the world, causing substantial patient morbidity and mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to distant sites, with metastatic diseases accounting for a vast ...
Amedei, A., Amin, A., Ashraf, S., Dhawan, P., et al., Fujii, H., Georgakilas, A., Gieseler, F., Honoki, K., Jiang, W., Katoh, M., Niccolai, E., Prince, M., Sanders, A., Sarkar, M., Sliva, D., Spano, D., Subbarayan, P., Thompson, S., Ungefroren, H., Zollo, M.   +20 more
core   +1 more source

Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression

Journal of Pharmacological Sciences, 2008
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen, Jian-Wen Liu, Jian-Jiang Zhong   +2 more
doaj   +1 more source

Comprehensive Evaluation of Fructus Tsaoko, Seeds of Tsaoko Fructus and Ginger Made Seeds of Tsaoko Fructus Based on Drug‐Like Compounds and Aroma Analysis

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study mainly consists of two parts. First, after screening for drug‐like metabolites via LC–MS and GC–MS, a comprehensive evaluation model was established using a principal component analysis‐based weighted scoring method, by which the drug‐likeness ranking of three samples was determined.
Han Chen, Meiquan Yang, Weize Yang, Mingju Qi, Zongliang Xu, Tianmei Yang, Jinyu Zhang   +6 more
wiley   +1 more source