Results 61 to 70 of about 10,080 (200)

A Triterpenoid‐Enriched GLE70 Fraction From Ganoderma lingzhi Ameliorates Alcoholic Liver Disease via Multi‐Target Regulation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
GLE fractions were prepared from Ganoderma lingzhi using gradient ethanol elution and evaluated for their biological activities. Among the fractions, GLE70 exhibited the strongest antioxidant and hepatoprotective effects. Integrated chemical characterization, network pharmacology, molecular docking, and in vivo validation suggested that GLE70 may exert
Yanjun Chen, Wenjia Li, Shiyi Ye, Jiaxue Li, Xiaobing Song, Qianli Ma, Ping Chen, Biying Zhang   +7 more
wiley   +1 more source

Application of Electronic tongue and HPLC in rapid determination of functional triterpenes and origins of Ganoderma lucidum

Frontiers in Nutrition
IntroductionGanoderma lucidum is one well known functional food resource. The triterpenes, such as Ganoderic acid A and Ganoderic acid D, as well as the sensory characteristics could reflect the quality of G. lucidum.MethodsIn order to find rapid methods
Jing Tian, Jing Tian, Jinfeng Wei, Yuxin Liu, Yuxin Liu, Changqin Li, Changqin Li, Changqin Li, Changqin Li, Changyang Ma, Changyang Ma, Changyang Ma, Changyang Ma, Wenyi Kang, Wenyi Kang, Wenyi Kang, Wenyi Kang   +16 more
doaj   +1 more source

Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi

Molecules, 2016
Triterpene acids (TAs) are the major bioactive constituents in the medicinal fungus Ganoderma lingzhi. However, fermentative production of TAs has not been optimized for commercial use, and whether the TAs isolated from G.
Xiao-Ling Wang, Zhong-Yang Ding, Gao-Qiang Liu, Hailong Yang, Guo-Ying Zhou   +4 more
doaj   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Establishment of the fingerprint of ganoderma lucidum spore powder and study on the anti-inflammatory activity of ganoderma lucidum spore oil

Guoji laonian yixue zazhi
[Objective] Establishment of a fingerprinting assay for Ganoderma lucidum spore powder and investigation of the effects of Ganoderma lucidum spore oil on the inflammatory factors IL-1β, IL-6, and TNF-α.
Yu Zhang, Lihui Hou, Le Wang, Yunshan Si, Hongjuan Wen, Ying Gao, Xiuhua Yu   +6 more
doaj   +1 more source

Ethanol Extract From Ganoderma atrum Alleviates Obesity Through Modulating Gut Microbiota and Metabolism

Food Frontiers, Volume 7, Issue 2, March 2026.
EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang, Chenqing Xu, Siying Wu, Steve W. Cui, Shaoping Nie   +4 more
wiley   +1 more source

Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum

, 2009
Investigations on Ganoderma lucidum fermentation suggested that the responses of the cell growth and metabolites biosynthesis to pH and dissolved oxygen tension (DOT) were different. The ganoderic acid (GA) production of 321.6 mg/L was obtained in the pH-
Zhong, Jian-Jiang, Zhang, Wei, Tang, Ya-Jie, Tang, YJ   +3 more
core   +1 more source

Genetic engineering ofGanoderma lucidumfor the efficient production of ganoderic acids [PDF]

Bioengineered, 2015
Ganoderma lucidum is a well-known traditional medicinal mushroom that produces ganoderic acids with numerous interesting bioactivities. Genetic engineering is an efficient approach to improve ganoderic acid biosynthesis. However, reliable genetic transformation methods and appropriate genetic manipulation strategies remain underdeveloped and thus ...
Jun-Wei, Xu, Jian-Jiang, Zhong
openaire   +2 more sources

Influence of cultivation substrate on antioxidant activities and triterpenoid profiles of the fruiting body of Ganoderma lucidum

Frontiers in Nutrition
IntroductionThe fruiting body of Ganoderma lucidum has been believed to possess a wide range of therapeutic effects. There are two main methods for artificial cultivation of G.
Gelian Luo, Zhibin Pan, Zhibin Liu, Weiqing Cheng, Tingting Yu   +4 more
doaj   +1 more source