Results 61 to 70 of about 10,827 (210)

Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer

Tumor Biology, 2017
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and exogenous stress by activating ...
Balraj Singh Gill, Sanjeev Kumar, Navgeet   +2 more
doaj   +1 more source

Delivering natural products and biotherapeutics to improve drug efficacy [PDF]

, 2017
Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery ...
Al Qaraghuli, Mohammed M., Alsaadi, Manal, Alzahrani, Abdullah R., Ferro, Valerie A., Niwasabutra, Kanidta, Obeid, Mohammad A.   +5 more
core   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]

, 2014
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod, A Berthod, A Koch, A Li, A Marston, A Maurya, A Peng, A Sun, ALM Nasser, AM Martin, AS Engelberth, AS Graham, B Diallo, B Diallo, B Medhi, B Pinel, BCB dos Santos, BK Gosse, C Zhao, CR Cheng, D Agostinho, D Du, D Fisher, D Grancher, D Wang, D Wang, D Wu, D Zhao, E Mudge, F Chen, F Chen, F Chen, F Fullas, F Gutiérrez, F He, F Oka, F Qiu, F Xiang, F Yang, G Tian, G Tian, G Wang, G Yan, GD Brown, GG Rocha, H Knapp, H Wu, H Ye, H Ye, H Zhang, HB Li, HB Li, HB Li, HB Li, HT Lu, I Slacanin, IA Sutherland, IA Sutherland, IA Sutherland, Ian Garrard, IJ Garrard, IJ Garrard, IJ Garrard, IJ Ha, J Hu, J Huang, J Liang, J Liu, J Ma, J Peng, J Wang, J Wang, J Wang, J Xie, J Xie, J Xu, J Yan, JCT Silva, JH Lee, JP Fan, JT Fischedick, JT Fischedick, JT Fischedick, K Skalicka-Woźniak, KD Yoon, KD Yoon, Krystyna Skalicka-Woźniak, KY Yoo, M Gu, M Gu, M Hamzaoui, M Lechtenberg, M Liu, M Puertas Mejia, MP Gasper, N Acton, N Fischer, N Frighetto, O Shehzad, O Shehzad, O Shehzad, O Shirota, O Shirota, P Hewitson, PA Souza De, PK Ajikumar, Q Chen, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, QB Han, QB Han, QB Han, R Aman, R Graziose, R Roscher, R Tsao, RTS Frighetto, S Baldermann, S Baldermann, S He, S Liu, S Shi, S Wu, S Wu, S Yao, S Yao, SM Kim, SS Cicek, SY Shi, T Abbott, VF Rodrigues, VGP Severino, VP da Silva, W He, X Cao, X Han, X Qi, X Shi, X Xiao, X Xin, XC Li, XH Xiao, XY Huang, Y Cheng, Y Cheng, Y Geng, Y Ikai, Y Ito, Y Ito, Y Ito, Y Ito, Y Jiang, Y Lu, Y Lu, Y Ma, Y Wang, Y Wei, Y Wei, Y Wei, Y Yang, Y Yang, Y Yuan, Y Zhang, Y Zhao, YW Ha, YW Ha, YY Dang, Z Jiang   +172 more
core   +2 more sources

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body

Frontiers in Microbiology, 2019
Ganoderma lingzhi is a famous medicinal mushroom used as Chinese medicine or functional food and has been accepted across the globe. It is important to enhance the contents of bioactive compounds, which in turn improves the quality and biological ...
Qingying Dong, Yueyue Li, Gaoqiang Liu, Zhiwei Zhang, Huabin Zhou, Hailong Yang   +5 more
doaj   +1 more source

Postharvest Drying Techniques Regulate Secondary Metabolites and Anti-Neuroinflammatory Activities of Ganoderma lucidum

Molecules, 2021
Ganoderma lucidum extract is a potent traditional remedy for curing various ailments. Drying is the most important postharvest step during the processing of Ganoderma lucidum.
Nooruddin-bin Sadiq, Da-Hye Ryu, Jwa-Yeong Cho, A-Hyeon Lee, Dae-Geun Song, Banzragch Dorjsembe, Jin-Chul Kim, Je-Hyeong Jung, Chu-Won Nho, Muhammad Hamayun, Seung-Hoon Yang, Ho-Youn Kim   +11 more
doaj   +1 more source

Ethanol Extract From Ganoderma atrum Alleviates Obesity Through Modulating Gut Microbiota and Metabolism

Food Frontiers, Volume 7, Issue 2, March 2026.
EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang, Chenqing Xu, Siying Wu, Steve W. Cui, Shaoping Nie   +4 more
wiley   +1 more source

Application of Electronic tongue and HPLC in rapid determination of functional triterpenes and origins of Ganoderma lucidum

Frontiers in Nutrition
IntroductionGanoderma lucidum is one well known functional food resource. The triterpenes, such as Ganoderic acid A and Ganoderic acid D, as well as the sensory characteristics could reflect the quality of G. lucidum.MethodsIn order to find rapid methods
Jing Tian, Jing Tian, Jinfeng Wei, Yuxin Liu, Yuxin Liu, Changqin Li, Changqin Li, Changqin Li, Changqin Li, Changyang Ma, Changyang Ma, Changyang Ma, Changyang Ma, Wenyi Kang, Wenyi Kang, Wenyi Kang, Wenyi Kang   +16 more
doaj   +1 more source

Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi

Molecules, 2016
Triterpene acids (TAs) are the major bioactive constituents in the medicinal fungus Ganoderma lingzhi. However, fermentative production of TAs has not been optimized for commercial use, and whether the TAs isolated from G.
Xiao-Ling Wang, Zhong-Yang Ding, Gao-Qiang Liu, Hailong Yang, Guo-Ying Zhou   +4 more
doaj   +1 more source