Results 41 to 50 of about 9,792 (169)

Induction of apoptosis and ganoderic acid biosynthesis by cAMP signaling in Ganoderma lucidum [PDF]

open access: yesScientific Reports, 2017
AbstractApoptosis is an essential physiological process that controls many important biological functions. However, apoptosis signaling in relation to secondary metabolite biosynthesis in plants and fungi remains a mystery. The fungusGanoderma lucidumis a popular herbal medicine worldwide, but the biosynthetic regulation of its active ingredients ...
Bang-Jau You   +6 more
openaire   +3 more sources

Synergistic effect of Ganoderma lucidum Triterpenoids and biosynthesized Zinc Oxide nanoparticles against some dermatophytes [PDF]

open access: yesNanomedicine Research Journal
G. lucidum mushroom has been recorded in conventional medicine for more than 2000 years due to has several bioactive compounds including triterpenoids (GLTs).
Hasan Kareem, Alaa Mohsin Al-Araji
doaj   +1 more source

A novel approach to enhancing ganoderic acid production by Ganoderma lucidum using apoptosis induction. [PDF]

open access: yesPLoS ONE, 2013
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and enhancing GA production are critical to using G.
Bang-Jau You   +7 more
doaj   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

open access: yesBioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen   +2 more
wiley   +1 more source

Ganoderic Acid DM: An Alternative Agent for the Treatment of Advanced Prostate Cancer [PDF]

open access: yesThe Open Prostate Cancer Journal, 2010
Prostate cancer is the most commonly diagnosed cancer in men and accounts for significant morbidity and mortality in the western world. While traditional therapies are effective at clearing early stage cancer, they often fail to treat late stage metastatic disease.
Benjamin M, Johnson   +3 more
openaire   +2 more sources

Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer

open access: yesTumor Biology, 2017
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and exogenous stress by activating ...
Balraj Singh Gill   +2 more
doaj   +1 more source

Postharvest Drying Techniques Regulate Secondary Metabolites and Anti-Neuroinflammatory Activities of Ganoderma lucidum

open access: yesMolecules, 2021
Ganoderma lucidum extract is a potent traditional remedy for curing various ailments. Drying is the most important postharvest step during the processing of Ganoderma lucidum.
Nooruddin-bin Sadiq   +11 more
doaj   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao   +4 more
wiley   +1 more source

Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression

open access: yesJournal of Pharmacological Sciences, 2008
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen   +2 more
doaj   +1 more source

The Potential Alleviating Property Against NAFLD by Ganoderma lucidum With Bacteria‐Enzyme Synergistic Fermentation

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
A bacteria‐enzyme synergistic fermentation process using Lactobacillus rhamnosus was developed to produce fermented Ganoderma lucidum broth (FBG), which significantly enriched ganoderic acid F compared to water extraction. In FFA‐induced HepG2 cells, FBG alleviated NAFLD‐related damage by reducing lipid deposition, ROS, MDA, TC, TG, and LDL‐C, while ...
Manhui Sun   +6 more
wiley   +1 more source

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