Results 31 to 40 of about 10,827 (210)
Ganoderic Acid in the Treatment of Prostate Cancer [PDF]
Jundishapur Journal of Natural Pharmaceutical Products, 2012 Prostate cancer is the most commonly diagnosed cancer in men and is the second most common cause of cancer-related deaths in the western world. Presently, the most common options for treatment are prostatectomy, radiation and chemotherapy. While certain immunotherapeutics have shown promise in clinical trials, the search for more effective, long-term ...
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Shipin yu jixie, 2023 Objective: Construction of a simple and rapid method for the analysis of ganoderic acid A （GAA）. Methods: The molecular imprinted polymer （MIP） that can specifically recognize ganoderic acid A （GAA） were prepared by cyclic voltammetric deposition using ...
HUANG Gui-zhen +5 more
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Frontiers in Microbiology, 2023 IntroductionThis study aimed to investigate the effects of different growth stages (booting period-SYK; initial flowering-SCK; full flowering-SSK) on the fermentation quality, microbial community, metabolic pathways and metabolomic characteristics of ...
Zhihui Fu +8 more
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Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum [PDF]
Microbial Cell Factories, 2019 Ganoderic acids (GAs), derived from the medicinal mushroom Ganoderma lucidum, possess anticancer and other important pharmacological activities. To improve production of GAs, a homologous farnesyl diphosphate synthase (FPS) gene was overexpressed in G. lucidum.
Yu Fei, Na Li, De-Huai Zhang, Jun-Wei Xu
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Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis [PDF]
International Journal of Molecular Sciences, 2021 Renal ischemia reperfusion injury (RIRI) is one of the main causes of acute kidney injury (AKI), which can lead to acute renal failure. The development of RIRI is so complicated that it involves many factors such as inflammatory response, oxidative stress and cell apoptosis.
Guangying Shao +11 more
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Telomerase-associated apoptotic events by mushroom Ganoderma lucidum on premalignant human urothelial cells [PDF]
, 2014 Author name used in this publication: Mayur Danny I.
Au, DWT, Gohel, MDI, Yuen, JWM
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Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice [PDF]
Bioscience Reports, 2019 AbstractThe present study aimed to investigate the protective effects of ganoderic acid A (GAA) on lipopolysaccharide (LPS)-induced acute lung injury. In mouse model of LPS-induced acute lung injury, we found that GAA led to significantly lower lung wet-to-dry weight ratio and lung myeloperoxidase activity, and attenuated pathological damages.
Bing Wan +10 more
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Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast
Nature Communications, 2022 AbstractType II ganoderic acids (GAs) produced by the traditional medicinal mushroom Ganoderma are a group of triterpenoids with superior biological activities. However, challenges in the genetic manipulation of the native producer, low level of accumulation in the farmed mushroom, the vulnerabilities of the farming-based supply chain, and the elusive ...
Wei Yuan +6 more
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Plants, 2023 Abiotic elicitation, a well-known strategy in mushroom biotechnology, promotes increased accumulation of secondary metabolites in mycelial cultures. The study aimed the effects of methyl jasmonate (MeJA) on the production of triterpenes in submerged ...
Katarzyna Sułkowska-Ziaja +7 more
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In Vitro Antitumor Effects of the Cold-Water Extracts of Mediterranean Species of Genus Pleurotus (Higher Basidiomycetes) on Human Colon Cancer Cells [PDF]
, 2014 The aim of the present study was to evaluate whether the cold-water extract of Pleurotus eryngii var. ferulae (CWE-Pef) and Pleurotus nebrodensis (CWE-Pn), two of the most prized wild and cultivated edible mushrooms can affect the tumour phenotype of ...
Alessandro, R. +8 more
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