Results 31 to 40 of about 10,080 (200)
Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma
Drug Delivery, 2019 This work evaluates nano-lipid carrier of ganoderic acid (GA) and molecular docking on various cancer signaling pathways, an attempt to improve the hepatic condition associated with hepatic carcinoma (HCC) induced by diethyl-nitrosamine (DEN) in Wistar ...
Mahfoozur Rahman +7 more
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Current Techniques for the Cultivation of Ganoderma lucidum for the Production of Biomass, Ganoderic Acid and Polysaccharides [PDF]
Food Technology and Biotechnology, 2003 Ganoderma lucidum is a medicinal mushroom that has been used in the Orient for more than 2000 years. Due to the long time required for basidiocarp formation, attention has recently been given to the use of submerged fermentation for the production of ...
Ricardo Wagner +4 more
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Shipin gongye ke-ji, 2023 The contents of polysaccharides, triterpenes, ganoderic acid A, ganoderic acid C1 and ganoderic acid F in Kangding Ganoderma leucocontextum were analyzed by pharmacopoeia and HPLC.
Boyu ZHU +8 more
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Ganoderic Acid A Metabolites and Their Metabolic Kinetics [PDF]
Frontiers in Pharmacology, 2017 Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by analyzing the bile, plasma and urine after intravenous administration to rats (20 mg ...
Cao, Fang-Rui +6 more
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Journal of Fungi, 2022 Ganoderic acid (GA) is an important secondary metabolite of Ganoderma lucidum with a diverse array of pharmacological properties. In this study, we found that exogenous ethylene increased the production of endogenous ethylene and ganoderic acid in G ...
Li Meng +7 more
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Data_Sheet_1_A methyltransferase LaeA regulates ganoderic acid biosynthesis in Ganoderma lingzhi.PDF
, 2022 The methyltransferase LaeA is a global regulator involved in the biosynthesis of secondary metabolites by ascomycete fungi. However, little is known of its regulatory role in basidiomycete fungi.
Na Li (6550) +2 more
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Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum [PDF]
Microbial Cell Factories, 2019 Ganoderic acids (GAs), derived from the medicinal mushroom Ganoderma lucidum, possess anticancer and other important pharmacological activities. To improve production of GAs, a homologous farnesyl diphosphate synthase (FPS) gene was overexpressed in G. lucidum.
Yu Fei, Na Li, De-Huai Zhang, Jun-Wei Xu
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Novel Glycosylation by Amylosucrase to Produce Glycoside Anomers
Biology, 2022 Glycosylation occurring at either lipids, proteins, or sugars plays important roles in many biological systems. In nature, enzymatic glycosylation is the formation of a glycosidic bond between the anomeric carbon of the donor sugar and the functional ...
Jiumn-Yih Wu +5 more
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A Review on the Sources, Structures, and Pharmacological Activities of Lucidenic Acids
Molecules, 2023 Ganoderma lucidum has long been used as a multi-purpose plant and functional food. The pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and triterpenoids.
Chengwen Zheng +7 more
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Ganoderic Acid in the Treatment of Prostate Cancer [PDF]
Jundishapur Journal of Natural Pharmaceutical Products, 2012 Prostate cancer is the most commonly diagnosed cancer in men and is the second most common cause of cancer-related deaths in the western world. Presently, the most common options for treatment are prostatectomy, radiation and chemotherapy. While certain immunotherapeutics have shown promise in clinical trials, the search for more effective, long-term ...
openaire +2 more sources