The effects of oleic acid addition methods on the metabolic flux distribution of ganoderic acids R, S and T’s biosynthesis from Ganoderma lucidum were investigated.
Meng-Qiu Yan +9 more
doaj +2 more sources
Ganoderic Acid Production via Aerial Co-cultivation of Ganoderma lucidum with Bacillus subtilis and Aspergillus niger Using Bubble Column Bioreactor [PDF]
Background and Objective: Ganoderma lucidum, with its medicinal characteristics, is one of the most beneficial fungi in traditional Asian medicine.
Soheil Kianirad +6 more
doaj +2 more sources
Synergistic Effect of Elicitors in Enhancement of Ganoderic Acid Production: Optimization and Gene Expression Studies [PDF]
Ganoderma lucidum is one of the most well-known fungi, and has many applications in medicine. Ganoderic acid is among the valuable secondary metabolites of Ganoderma lucidum, and responsible for the inhibition of the tumor cell growth and cancer ...
Motaharehsadat Heydarian +4 more
doaj +2 more sources
Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and exogenous stress by activating ...
Balraj Singh Gill +2 more
doaj +2 more sources
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen +2 more
doaj +2 more sources
Impact of Rifampin Induction on the Fermentation Production of Ganoderic Acids by Medicinal Mushroom Ganoderma lucidum [PDF]
Backgrounds and Objectives: Ganoderic acids are the most valuable secondary metabolites in Ganoderma lucidum traditional medicinal mushrooms, which have shown antitumor properties in many studies. However, application of ganoderic acids is limited due to
Fahimeh Nojoki +6 more
doaj +2 more sources
Glycosylation of Ganoderic Acid F by Bacillus Glycosyltransferase
Ganoderma lucidum is a medicinal fungus and has been used for improvements of health or prevention of certain diseases in Asia for thousands of years. Despite numerous kinds of triterpenoids having been identified from G. lucidum, few natural Ganoderma triterpenoids exist in the form of glycosides (saponins).
Te-Sheng Chang
openaire +2 more sources
A novel approach to enhancing ganoderic acid production by Ganoderma lucidum using apoptosis induction. [PDF]
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and enhancing GA production are critical to using G.
Bang-Jau You +7 more
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Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms [PDF]
To examine the composition of lanostanoids in Ganoderma lucidum, we have developed a liquid chromatography-mass spectrometry (LC-MS) method by using the ganoderic acids isolated in our laboratory as reference standards. The identity of 14 peaks in the high performance liquid chromatogram (HPLC) of G. lucidum has been confirmed.
Qi, Ying, Zhao, Lingling, Sun, Hao H.
openaire +4 more sources
Blue Light Receptor WC-2 Regulates Ganoderic Acid Biosynthesis in Ganoderma lingzhi [PDF]
Ganoderic acid (GA) is a key bioactive component with pharmacological properties that is found in Ganoderma lingzhi, a renowned medicinal mushroom. Currently, the regulatory mechanisms underlying GA biosynthesis in G.
Yan Xu +5 more
doaj +2 more sources

