Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma [PDF]
Drug Delivery, 2019 This work evaluates nano-lipid carrier of ganoderic acid (GA) and molecular docking on various cancer signaling pathways, an attempt to improve the hepatic condition associated with hepatic carcinoma (HCC) induced by diethyl-nitrosamine (DEN) in Wistar ...
Mahfoozur Rahman +7 more
doaj +5 more sources
Biotransformation of Ganoderic Acid A to 3-O-Acetyl Ganoderic Acid A by Soil-isolated Streptomyces sp. [PDF]
Fermentation, 2018 The medicinal fungus Ganoderma lucidum contains many bioactive triterpenoids, ganoderic acid A (GAA) being one of the major ones. The present study explored the microbial biotransformation of GAA, isolating 283 strains of soil actinomycetes and ...
Te-Sheng Chang +4 more
doaj +2 more sources
Blue Light Receptor WC-2 Regulates Ganoderic Acid Biosynthesis in Ganoderma lingzhi [PDF]
Journal of FungiGanoderic acid (GA) is a key bioactive component with pharmacological properties that is found in Ganoderma lingzhi, a renowned medicinal mushroom. Currently, the regulatory mechanisms underlying GA biosynthesis in G.
Yan Xu +5 more
doaj +2 more sources
Ganoderic Acid Production via Aerial Co-cultivation of Ganoderma lucidum with Bacillus subtilis and Aspergillus niger Using Bubble Column Bioreactor [PDF]
Applied Food BiotechnologyBackground and Objective: Ganoderma lucidum, with its medicinal characteristics, is one of the most beneficial fungi in traditional Asian medicine.
Soheil Kianirad +6 more
doaj +3 more sources
ExplorationNeuroinflammation plays a critical role in cerebral ischemic injury, making it an important therapeutic target for stroke treatment. Ganoderic acids (GAs), the primary bioactive compounds isolated from Ganoderma lucidum, exhibit well‐demonstrated anti ...
Ang Ma +17 more
doaj +2 more sources
Ganoderic acid B’s influence towards the therapeutic window of trifluoperazine (TFP) [PDF]
African Health Sciences, 2015 Background: Ganoderic acid B is an important bioactive ingredient isolated from Ganoderma lucidum, and exhibits various pharmacological activities.Aims: To investigate the influence of Ganoderic acid B towards the therapeutic window of trifluoperazine ...
Guo, J, Liu, T, Liu, X, Ni, C
core +5 more sources
The Efficacy & Molecular Mechanisms of a Terpenoid Compound Ganoderic Acid C1 on Corticosteroid-Resistant Neutrophilic Airway Inflammation: In vivo and in vitro Validation [PDF]
Journal of Inflammation ResearchZhen-Zhen Wang,1– 3,* Hang Li,4,* Anish R Maskey,2,* Kamal Srivastava,2,5,* Changda Liu,6,* Nan Yang,2,5 Taoyun Xie,7 Ziyi Fu,8 Junxiong Li,9 Xiaohong Liu,10 Hugh A Sampson,6 Xiu-Min Li2,11 1Academy of Chinese Medical Science, Henan ...
Wang ZZ +11 more
doaj +2 more sources
Glycosylation of Ganoderic Acid G by Bacillus Glycosyltransferases. [PDF]
Int J Mol Sci, 2021 Ganoderma lucidum is a medicinal fungus abundant in triterpenoids, its primary bioactive components. Although numerous Ganoderma triterpenoids have already been identified, rare Ganoderma triterpenoid saponins were recently discovered. To create novel Ganoderma saponins, ganoderic acid G (GAG) was selected for biotransformation using four Bacillus ...
Wu JY +4 more
europepmc +5 more sources
Ganoderic Acid A Alleviates OVA-Induced Asthma in Mice. [PDF]
Inflammation, 2021 AbstractThe aim of this study is to investigate the effects of ganoderic acid A (GAA) on OVA-induced asthma in mice. Mouse asthma model was established by ovalbumin (OVA) in vitro. Diff-Quik staining was used to observe the total numbers of cells and the number of classification cells in each group, and HE staining was used to observe lung inflammation
Lu X, Xu C, Yang R, Zhang G.
europepmc +4 more sources
Shipin gongye ke-ji, 2023 The contents of polysaccharides, triterpenes, ganoderic acid A, ganoderic acid C1 and ganoderic acid F in Kangding Ganoderma leucocontextum were analyzed by pharmacopoeia and HPLC.
Boyu ZHU +8 more
doaj +1 more source