Results 81 to 90 of about 2,525,777 (194)
Journal of Neurochemistry, Volume 170, Issue 4, April 2026.Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich +2 more
wiley +1 more source
Synthesis of ganoderic acid analogues to investigate their activity as anti-prostate cancer agents [PDF]
, 2019 Cancers are one of the leading causes of premature human death globally. Prostate cancer is the second most common cancer in the world; chemoprevention can help decrease the proportion of fatal cases and prevent recurrence of the cancer.
Al-Obaidi, Mohammed
core
Food Frontiers, Volume 7, Issue 2, March 2026.EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang +4 more
wiley +1 more source
Effect of aspirin concentration on the accumulation of ganoderic acids and fungal biomass.
, 2013 Fungal mycelium was cultured on PDA for 4 days and then incubated with 0.5–8 mM aspirin for additional 1 day. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs) (C)
Hui-Chuan Hsieh (289703) +7 more
core +1 more source
Time course of ganoderic acids and fungal biomass production of Ganoderma lucidum cultured on PDA.
, 2013 Ganoderma lucidum was cultured on potato dextrose agar (PDA) for 1 to 6 weeks. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs) (C) were evaluated.
Hui-Chuan Hsieh (289703) +7 more
core +1 more source
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Anticancer Activity of Ganoderic Acid DM: Current Status and Future Perspective
Journal of Clinical & Cellular Immunology, 2017 Ganoderma lucidum is a mushroom that has a long history of medicinal use in the Far East countries as this mushroom is revered for its supposed miracle cures and life improving properties. Recently, this mushroom has come under scientific scrutiny to examine the possibility of finding biologically active compounds that may have an impact on human ...
Bryant, John Matthew +2 more
openaire +2 more sources
Scientific ReportsSevere burns can cause secondary pulmonary inflammation driven by endotoxin-related inflammatory activation and oxidative stress. Here, we integrated untargeted LC-MS, network pharmacology, transcriptomics, molecular docking, molecular dynamics ...
Jian Zhang +5 more
doaj +1 more source
, 2017 Putrescine is an important polyamine that participates in a variety of stress responses. Ornithine decarboxylase (ODC) is a key enzyme that catalyzes the biosynthesis of putrescine. A homolog of the gene encoding ODC was cloned from Ganoderma
Ang Ren +7 more
core +1 more source
Effect of fungal culture age on ganoderic acids induction by aspirin in Ganoderma lucidum.
, 2013 Fungal mycelium cultured on PDA for 4–12 days was incubated with 4 mM aspirin for additional 1 day. Fungal biomass (A), lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) production (B) and total ganoderic acids (total GAs) production (C) by
Hui-Chuan Hsieh (289703) +7 more
core +1 more source