Results 91 to 100 of about 2,525,777 (194)

Multi‐Omics Analysis Reveals the Potential Preventive Mechanism of Lactobacillus salivarius Li01 Against L‐Arginine‐Induced Acute Pancreatitis in Mice

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
This study reveals that Lactobacillus salivarius Li01 alleviates acute pancreatitis by increasing gut Paramuribaculum. This modulation of the microbiota and its steroid hormone metabolites suppresses the pancreatic TNF signaling pathway, uncovering a protective ‘gut‐metabolism‐immunity’ axis.
Jiamin Duan, Jing Lou, Feiyu Wang, Huiyong Jiang, Longxian Lv, Hongwei Fu   +5 more
wiley   +1 more source

Pharmacokinetics of Ganoderic Acids A and F after Oral Administration of Ling Zhi Preparation in Healthy Male Volunteers [PDF]

, 2020
The objectives of this paper were to evaluate the pharmacokinetics of ganoderic acids A and F after a single oral dose of the water extract of MG2-strain Ling Zhi (MG2FB-WE) and to assess the influence of food on the pharmacokinetics in 12 healthy male ...
Chaichan Sangdee, Chadarat Ampasavate, Natthakarn Chiranthanut, Noppamas Rojanasthien, Supanimit Teekachunhatean, Sasinun Sadja   +5 more
core  

Ganoderic acid A alleviate psoriasis by inhibiting GSDMD-mediated pyroptosis

Tissue and Cell
Psoriasis is a chronic inflammatory dermatological condition characterized by the infiltration of inflammatory cells into the dermal layer. This study aimed to elucidate the anti-inflammatory properties and underlying molecular mechanisms of Ganoderic acid A in the treatment of psoriasis.A psoriasis model was induced in mice using IMQ to evaluate the ...
Chenggen Xiao, Junchen Chen, Xingchen Zhou, Hong Liu   +3 more
openaire   +2 more sources

Time course of ganoderic acids and fungal biomass production of Ganoderma lucidum incubated with aspirin.

, 2013
Fungal mycelium was cultured on PDA for 4 days and then incubated with 4 mM aspirin for additional 6 to 48 hr. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs ...
Hui-Chuan Hsieh (289703), Ni Tien (289701), Hong-Zin Lee (280194), Yu-Lin Chung (289705), Lin-Hsien Tseng (289704), Meng-Shiou Lee (289702), Bang-Jau You (276811), Miin-Huey Lee (289700)   +7 more
core   +1 more source

MOESM1 of Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum

, 2019
Additional file 1: Figure S1. (A) The expression vector pJW-EXP-FPS. (B) Identification and characterization of the FPF gene-overexpressing strain. Amplification pattern of genomic PCR obtained with primers for the fusion of the gpd promoter and FPS gene fragment from different strains.
Fei, Yu, Li, Na, Zhang, De-Huai, Xu, Jun-Wei   +3 more
openaire   +1 more source

Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study

Tumor Biology, 2016
Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration in the RTK signaling modulates the downstream signaling pathways that results in cancer.
Balraj Singh, Gill, , Navgeet, Sanjeev, Kumar   +2 more
openaire   +2 more sources

Esteróis e triterpenos de Ganoderma australe (Fr.) Pat. com perspectivas de uso medicinal [PDF]

, 2000
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.Com o objetivo de verificar a presença de triterpenóides bioativos em G.
Gerber, Alexandra Lehmkuhl
core  

Ethanolic Extract of Ganoderma mexicanum Pat. Mycelium: A Source of Bioactive Compounds with Antiproliferative Activity and Potential PPAR-γ Natural Ligands

Pharmaceuticals
Background/Objective: Ganoderma spp. have long been studied for their bioactive pharmacological properties, and their biomass and extracts have been obtained from various sources.
Lucia T. Angulo-Sanchez, Max Vidal-Gutiérrez, Heriberto Torres-Moreno, Martín Esqueda, Aldo Gutiérrez, Georgina Vargas, Juan Luis Monribot-Villanueva, José A. Guerrero-Analco, César Muñoz-Bacasehua, Ramón Enrique Robles-Zepeda   +9 more
doaj   +1 more source

Ganoderic Acid X, a Lanostanoid Triterpene, Inhibits Topoisomerases and Induces Apoptosis of Cancer Cells

, 2009
Lanostanoid triterpenes isolated from Ganoderma amboinense were found to inhibit the growth of numerous cancer cell lines, and some of them inhibited the activities of topoisomerases I and II?? in vitro.
方偉宏;蔡克嵩;林淑萍;甘魯生, FANG, WOEI-HORNG;TSAI, KEH-SUNG;LIN, SHWU-BIN;KAN, LOU-SING   +1 more
core   +1 more source

Promotion of ganoderic acid production in Ganoderma sinense by the addtion of an ether extract from Eupolyphaga sinensis, a medicinal insect [PDF]

, 2013
To screen stimulators from Chinese medicinal insects for mycelial growth and ganoderic acid (GA) production by Ganoderma sinense, the fungus was inoculated into the media with and without supplementation of a medicinal insect extract.
Zhang, YG, Han, WJ, Zhang, HY, Wang, XL, Wu, TH, Liu, GQ   +5 more
core   +1 more source