Results 91 to 100 of about 701,063 (234)

Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation

Cell Proliferation, Volume 58, Issue 9, September 2025.
Sirt3 deacetylated SOD2 via K68 to orchestrate P.g.‐impaired cementogenesis. Reestablishment of the Sirt3/SOD2 axis by honokiol reduced SOD2 acetylation and facilitated cementogenesis. ABSTRACT The keystone pathogen Porphyromonas gingivalis (P.g.) is responsible for cementum resorption in periodontitis; however, the mechanism involved in it remains ...
Xin Huang, Huiqing Gou, Jirong Xie, Yonglin Guo, Yifei Deng, Yan Xu, Zhengguo Cao   +6 more
wiley   +1 more source

Jianpi‐Huogu Prescription Repairs Nontraumatic Osteonecrosis of the Femoral Head by Inhibiting NAMPT/STK11/HMGCR/ACAT1 Axis‐Mediated Lipid Production

Journal of Cellular and Molecular Medicine, Volume 29, Issue 18, September 2025.
ABSTRACT Jianpi‐Huogu Prescription (JHP), integrating the classic Chinese herbal formulas Linggui‐Zhugan Decoction and Si‐Wu Decoction, has shown clinical efficacy in treating early nontraumatic osteonecrosis of the femoral head (NONFH). In this study, 299 chemical constituents of JHP were identified using ultra‐performance liquid chromatography ...
Tao Li, Zhaochen Ma, Shuangrong Gao, Chu Zhang, Yan Jia, Huang Feng, Na Lin, Weiheng Chen, Yanqiong Zhang   +8 more
wiley   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, Volume 12, Issue 31, August 21, 2025.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus [PDF]

, 2016
Relative concentration of metabolites identified in Vibrio parahaemolyticus ATCC17802. (XLSX 113 kb)
Bo Feng, Weijia Zhang, Yingjie Pan, Yong Zhao, Zhuoran Guo   +4 more
core   +3 more sources

Ganoderma Sinense Soluble Dietary Fiber Alleviates Nonalcoholic Fatty Liver Disease by Regulating Liver Metabolism

eFood, Volume 6, Issue 4, August 2025.
This study evaluated the effect of soluble dietary fiber from Ganoderma sinense on nonalcoholic fatty liver disease (NAFLD) by establishing in vitro cell and in vivo mouse models. Ganoderma sinense soluble dietary fiber (GSSDF) alleviates nonalcoholic fatty liver disease by regulating lipid metabolism and reducing oxidative stress.
Ping Shao, Ying Yang, Zhenhao Li, Jihong Yang, Guoliang Zhang, Jianhua Zhang, Mengyao Wang   +6 more
wiley   +1 more source

Glycosylation of Ganoderic Acid A via Recombinant Glycosyltransferase of Bacillus subtilis Under Acidic Operating Condition

The FASEB Journal, 2020
Ganoderic acid A (GAA) is a triterpenoid with identified effective activity, isolated from Ganoderma lucidum . Glycosylation of triterpenoid might improve its anti‐toxin bioactivity and also increase both water solubility and physical‐chemical ...
Jiumn-Yih Wu, Te-Sheng Chang, Chien-Min Chiang, Tzi-Yuan Wang   +3 more
openaire   +1 more source

In vitro effects of Ganoderic acid A on NF-κB-mediated inflammatory response in caerulein-stimulated pancreatic acinar cells

Signa Vitae
This study aimed to investigate Ganoderic acid A’s (GAA) possible effects on inflammation and oxidative stress of caerulein-stimulated pancreatic acinar cells and uncover its effects on acute pancreatitis (AP).
Yuzhou Jin, Jin Huang, Na Ma
semanticscholar   +1 more source

MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

Exploration, Volume 5, Issue 4, August 2025.
Our findings suggest that miR‐29a/b is a critical regulator of CD8+ T cells, possibly via the Ifng‐JAK‐STAT signal in IBD patients and the upregulation of miR‐29a/b relieves the development of significant inflammation in the colon of DSS‐induced colitis‐affected mice.
Yingying Lin, Yuqi Wang, Yuning Zhang, Yao Lu, Juan Chen, Yongting Luo, Jian He, Qingfeng Luo, Heng Quan, Weiru Yu, Yujia Luo, Peng Xue, Yi Xue, Xiaoya Lin, Rui Ding, Lining Chen, Yiran Wang, Zenghui Xia, Liang Zhao, Hao Zhang, Ran Wang, Qingyu Wang, Xifan Wang, Jiaqi Su, Fazheng Ren, Cong Lv, Yixuan Li, Huiyuan Guo   +27 more
wiley   +1 more source

Ganoderic acid G and I and ganolucidic acid A and B, new triterpenoids from Ganoderma lucidum.

Chemical and Pharmaceutical Bulletin, 1985
Four new highly oxidized lanostane-type triterpenoids, ganoderic acid G and I and ganolucidic acid A and B, were isolated from the fungus ganoderma lucidum and their structures were elucidated on the basis of spectral evidence.
Tohru Kikuchi, Satoko Matsuda, Yoshihiro Murai, Zenichi Ogita   +3 more
openaire   +2 more sources

Potential Active Compounds of Ganoderma lucidum and Their Anticancer Effects: A Comprehensive Review

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This paper systematically discusses various active compounds within Ganoderma lucidum and their application in the treatment of tumor diseases. ABSTRACT The incidence and mortality rates of cancer patients continue to rise. Although many physical and chemical therapies, such as targeted tumor treatments, are effective against cancer, they are often ...
Yuan Liu, Sizhu Ren, Qing Sang, Xi Cheng, Yanmeng Bi   +4 more
wiley   +1 more source