Results 61 to 70 of about 6,455 (147)
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
MoleculesNeurodegenerative diseases represent a cluster of conditions characterized by the progressive degeneration of the structure and function of the nervous system.
Wenhui Lian +9 more
doaj +1 more source
Microbial Biotechnology, Volume 19, Issue 1, January 2026.This study reveals that Lactobacillus salivarius Li01 alleviates acute pancreatitis by increasing gut Paramuribaculum. This modulation of the microbiota and its steroid hormone metabolites suppresses the pancreatic TNF signaling pathway, uncovering a protective ‘gut‐metabolism‐immunity’ axis.
Jiamin Duan +5 more
wiley +1 more source
Redox Biology, 2018 Ganoderma lucidum has high commercial value because it produces many active compounds, such as ganoderic acids (GAs). Salicylic acid (SA) was previously reported to induce the biosynthesis of GA in G. lucidum.
Rui Liu +9 more
doaj +1 more source
Journal of Phytopathology, Volume 174, Issue 1, January/February 2026.ABSTRACT This study aimed to evaluate the potential of the mycelial growth filtrate (MGF) from Ganoderma lucidum in providing systemic protection to tomato plants against Septoria lycopersici‐induced leaf spot and inhibiting the production of reproductive structures by the phytopathogen. In greenhouse experiments, foliar application of MGF at 40% (v/v)
Mycheli P. Cruz +3 more
wiley +1 more source
Possibility of modernization of Ganoderma lucidum strains substrate
International Journal of Horticultural Science, 2005 Ganoderma lucidum (Reishi mushroom), the object of our experiments, is also known to contain medicinal compounds. This fungus has been used for many centuries as medicine in China.
P. Maszlavér +3 more
doaj +1 more source
Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review
BioMed Research International, Volume 2026, Issue 1, 2026.All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh +3 more
wiley +1 more source
Synthesis and biological evaluation of natural and synthetic ganoderic acids [PDF]
, 2017 Ganoderma lucidum also known as lingzhi or mushroom of immortality in East Asia countries, has been known for over 2000 years. Ganoderic acids (GA), which are important secondary metabolites of this mushroom, are highly oxygenated lanostane-type ...
Jaramillo Forcada, Tatiana
core
Food Frontiers, Volume 6, Issue 6, Page 3108-3121, November 2025.Ganoderic acid A (GA) improved lipid metabolism disorders by inhibiting intestinal FXR. GA markedly suppressed the ileal intestinal FXR activity. Then, GA changed bile acid composition and upregulated hepatic Cyp7a1 mRNA through decreasing FXR target genes encoded protein levels.
Feng Lu +7 more
wiley +1 more source
Medicinal Plant BiologyGanoderic acids (GAs) are bioactive compounds in Ganoderma lucidum that have various pharmacological properties. Their biosynthesis is influenced by environmental factors and elicitors, but the synergistic effects of multiple inducers on GA accumulation ...
Yanhong Guo +7 more
doaj +1 more source