Results 51 to 60 of about 6,455 (147)

Evaluation of the antimicrobial properties of natural extracts of Ganoderma lucidum

Tecnología en Marcha
There is a growing importance of alternative anticancer and anti-inflammatory treatments. Current interest lies in natural medicine and secondary metabolites present in plants, particularly focusing on triterpenes. Ganoderma lucidum is a fungal species
Karina Abarca-Cascante, Nicole Arias-Espinoza, Judith Cambronero-Vega, Bryan Zúñiga-Gaitán, Victor Álvarez-Valverde, José B Azofeifa-Bolaños, Jorengeth Rodríguez-Rodríguez   +6 more
doaj   +1 more source

High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body

Frontiers in Microbiology, 2019
Ganoderma lingzhi is a famous medicinal mushroom used as Chinese medicine or functional food and has been accepted across the globe. It is important to enhance the contents of bioactive compounds, which in turn improves the quality and biological ...
Qingying Dong, Yueyue Li, Gaoqiang Liu, Zhiwei Zhang, Huabin Zhou, Hailong Yang   +5 more
doaj   +1 more source

Effects of growth stage on the fermentation quality, microbial community, and metabolomic properties of Italian ryegrass (Lolium multiflorum Lam.) silage

Frontiers in Microbiology, 2023
IntroductionThis study aimed to investigate the effects of different growth stages (booting period-SYK; initial flowering-SCK; full flowering-SSK) on the fermentation quality, microbial community, metabolic pathways and metabolomic characteristics of ...
Zhihui Fu, Lin Sun, Zhijun Wang, Jingyi Liu, Meiling Hou, Qiang Lu, Junfeng Hao, Yushan Jia, Gentu Ge   +8 more
doaj   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Time course of ganoderic acids and fungal biomass production of Ganoderma lucidum incubated with aspirin.

, 2013
Fungal mycelium was cultured on PDA for 4 days and then incubated with 4 mM aspirin for additional 6 to 48 hr. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs ...
Hui-Chuan Hsieh (289703), Ni Tien (289701), Hong-Zin Lee (280194), Yu-Lin Chung (289705), Lin-Hsien Tseng (289704), Meng-Shiou Lee (289702), Bang-Jau You (276811), Miin-Huey Lee (289700)   +7 more
core   +1 more source

Ethanol Extract From Ganoderma atrum Alleviates Obesity Through Modulating Gut Microbiota and Metabolism

Food Frontiers, Volume 7, Issue 2, March 2026.
EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang, Chenqing Xu, Siying Wu, Steve W. Cui, Shaoping Nie   +4 more
wiley   +1 more source

Chemodiversity, pharmacological activity, and biosynthesis of specialized metabolites from medicinal model fungi Ganoderma lucidum

Chinese Medicine
Ganoderma lucidum is a precious fungus, particularly valued for its dual use as both medicine and food. Ganoderic acids (GAs), the distinctive triterpenoids found in the Ganoderma genus, exhibit a wide range of pharmacological activities.
Yupeng Du, Lixia Tian, Yu Wang, Zhenhao Li, Zhichao Xu   +4 more
doaj   +1 more source

Ganoderic Acid A Enhances Glycometabolism in Mouse Gastrocnemius Muscle During Exercise‐Induced Fatigue via AMPK/PGC‐1α Pathway Activation

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study investigated the effects of GAA, an active ingredient in Ganoderma lucidum, on exercise‐induced fatigue. GAA effectively enhances exercise performance by improving endurance duration while simultaneously reducing metabolic byproducts and muscle fiber damage.
Jialin Zhu, Fenglin Peng, Lin Zhang, Yanju Guo, Weiguo Liu, Jingrong Li, Shuju Shang, Bohan Zhang, Taotao Qiu   +8 more
wiley   +1 more source

Modulation of gut microbiota and lipid metabolism in rats fed high-fat diets by Ganoderma lucidum triterpenoids

Current Research in Food Science, 2023
Ganoderma lucidum triterpenoids (GP) have been reported to help prevent and improve hyperlipidemia. Modulation of the gut microbiota was proposed as underlying factor as well as a novel measure to prevent and treat hyperlipidemia.
Aijun Tong, Weihao Wu, Zhengxin Chen, Jiahui Wen, Ruibo Jia, Bin Liu, Hui Cao, Chao Zhao   +7 more
doaj   +1 more source