Results 51 to 60 of about 6,418 (158)

Comprehensive Evaluation of Fructus Tsaoko, Seeds of Tsaoko Fructus and Ginger Made Seeds of Tsaoko Fructus Based on Drug‐Like Compounds and Aroma Analysis

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study mainly consists of two parts. First, after screening for drug‐like metabolites via LC–MS and GC–MS, a comprehensive evaluation model was established using a principal component analysis‐based weighted scoring method, by which the drug‐likeness ranking of three samples was determined.
Han Chen, Meiquan Yang, Weize Yang, Mingju Qi, Zongliang Xu, Tianmei Yang, Jinyu Zhang   +6 more
wiley   +1 more source

Impact of Rifampin Induction on the Fermentation Production of Ganoderic Acids by Medicinal Mushroom Ganoderma lucidum

Applied Food Biotechnology, 2016
Backgrounds and Objectives: Ganoderic acids are the most valuable secondary metabolites in Ganoderma lucidum traditional medicinal mushrooms, which have shown antitumor properties in many studies. However, application of ganoderic acids is limited due to
Fahimeh Nojoki, Ashrafalsadat Hatamian-Zarmi, Mohammad Mir-Drikvand, Bahman Ebrahimi-Hosseinzadeh, Zahra-begom Mokhtari-Hosseini, Saeed Kalantari-Dehaghi, Maryam Esmaeilifar   +6 more
doaj  

Effects of growth stage on the fermentation quality, microbial community, and metabolomic properties of Italian ryegrass (Lolium multiflorum Lam.) silage

Frontiers in Microbiology, 2023
IntroductionThis study aimed to investigate the effects of different growth stages (booting period-SYK; initial flowering-SCK; full flowering-SSK) on the fermentation quality, microbial community, metabolic pathways and metabolomic characteristics of ...
Zhihui Fu, Lin Sun, Zhijun Wang, Jingyi Liu, Meiling Hou, Qiang Lu, Junfeng Hao, Yushan Jia, Gentu Ge   +8 more
doaj   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

Chemodiversity, pharmacological activity, and biosynthesis of specialized metabolites from medicinal model fungi Ganoderma lucidum

Chinese Medicine
Ganoderma lucidum is a precious fungus, particularly valued for its dual use as both medicine and food. Ganoderic acids (GAs), the distinctive triterpenoids found in the Ganoderma genus, exhibit a wide range of pharmacological activities.
Yupeng Du, Lixia Tian, Yu Wang, Zhenhao Li, Zhichao Xu   +4 more
doaj   +1 more source

The influence of extraction parameters on physicochemical properties of special grain brandies with Ganoderma lucidum [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2016
Ganoderma lucidum is one of the five major medicinal mushrooms. In Asian countries, alcoholic beverages with Ganoderma are traditionally produced and sold in local markets as a symbol of healthy products. The aim of this study was to examine the
Pecić Sonja, Nikićević Ninoslav, Veljović Mile, Jardanin Milka, Tešević Vele, Belović Miona, Nikšić Miomir   +6 more
doaj   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Ethanol Extract From Ganoderma atrum Alleviates Obesity Through Modulating Gut Microbiota and Metabolism

Food Frontiers, Volume 7, Issue 2, March 2026.
EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang, Chenqing Xu, Siying Wu, Steve W. Cui, Shaoping Nie   +4 more
wiley   +1 more source

Ganoderic Acid A Enhances Glycometabolism in Mouse Gastrocnemius Muscle During Exercise‐Induced Fatigue via AMPK/PGC‐1α Pathway Activation

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study investigated the effects of GAA, an active ingredient in Ganoderma lucidum, on exercise‐induced fatigue. GAA effectively enhances exercise performance by improving endurance duration while simultaneously reducing metabolic byproducts and muscle fiber damage.
Jialin Zhu, Fenglin Peng, Lin Zhang, Yanju Guo, Weiguo Liu, Jingrong Li, Shuju Shang, Bohan Zhang, Taotao Qiu   +8 more
wiley   +1 more source

The Biological Activity of Ganoderma lucidum on Neurodegenerative Diseases: The Interplay between Different Active Compounds and the Pathological Hallmarks

Molecules
Neurodegenerative diseases represent a cluster of conditions characterized by the progressive degeneration of the structure and function of the nervous system.
Wenhui Lian, Xu Yang, Qidong Duan, Jie Li, Yuting Zhao, Chunhui Yu, Tianzhu He, Tianxia Sun, Yu Zhao, Weinan Wang   +9 more
doaj   +1 more source