Ganoderic Acid in the Treatment of Prostate Cancer [PDF]
Prostate cancer is the most commonly diagnosed cancer in men and is the second most common cause of cancer-related deaths in the western world. Presently, the most common options for treatment are prostatectomy, radiation and chemotherapy. While certain immunotherapeutics have shown promise in clinical trials, the search for more effective, long-term ...
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Improved ganoderic acids production in Ganoderma lucidum by wood decaying components. [PDF]
AbstractGanoderma lucidumis a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs). GAs are largely produced in the mushroom primordium and fruiting body but much less in mycelium stage. However, little is known on the underlying regulatory mechanism.
Hu Y +7 more
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Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice [PDF]
Abstract The present study aimed to investigate the protective effects of ganoderic acid A (GAA) on lipopolysaccharide (LPS)-induced acute lung injury. In mouse model of LPS-induced acute lung injury, we found that GAA led to significantly lower lung wet-to-dry weight ratio and lung myeloperoxidase activity, and attenuated ...
Bing Wan +10 more
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Comprehensive Evaluation of Ganoderma Lucidum Infusion Products: Ganoderic Acid A Profiling, and Quality Indicators [PDF]
Reishi mushroom (Ganoderma lucidum) is widely consumed for its health benefits, mainly due to the presence of polysaccharides and triterpenoids. Among these, triterpenoids—especially ganoderic acids—are more easily extracted, which has led to the ...
Mohammad Faraji +3 more
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(1) Background: Ganoderic acids (GAs) are specific triterpenes of Ganoderma lucidum. The HPLC fingerprint profile of GAs of the fruiting body is well known, but their mycelial fingerprinting remains unclear.
Deng-Hai Chen +4 more
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Genetic engineering of Ganoderma lucidum for the efficient production of ganoderic acids. [PDF]
Ganoderma lucidum is a well-known traditional medicinal mushroom that produces ganoderic acids with numerous interesting bioactivities. Genetic engineering is an efficient approach to improve ganoderic acid biosynthesis. However, reliable genetic transformation methods and appropriate genetic manipulation strategies remain underdeveloped and thus ...
Xu JW, Zhong JJ.
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Glycosylation of Ganoderic Acid F by Bacillus Glycosyltransferase
Ganoderma lucidum is a medicinal fungus and has been used for improvements of health or prevention of certain diseases in Asia for thousands of years. Despite numerous kinds of triterpenoids having been identified from G. lucidum, few natural Ganoderma triterpenoids exist in the form of glycosides (saponins).
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Effect of selenium on main active component contents of Ganoderma lingzhi in different periods
Ganoderma lingzhi is one of the important edible and medicinal fungi with broad pharmacological activities, such as anti- tumor, immunity improvement and anti- oxidation, and also rich in selenium. Selenium is an essential trace element.
YE Liyun +4 more
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Determination of ganoderic acids in triterpenoid constituents of Ganoderma tsugae
Ganoderma product has the highest sale volume in the health food market in Taiwan. The most widely-used raw material is the species of G. tsuage. Nine triterpenoids were isolated from the fruiting body of G. tsugae and their structures were identified, using 1H NMR and FT-IR, as ganoderic acid A (1), B (2), C (3), D (4), E (5), C5 (6), C6 (7), G (8 ...
D.-H. Chen, W.K.-D. Chen
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Induction of apoptosis and ganoderic acid biosynthesis by cAMP signaling in Ganoderma lucidum [PDF]
AbstractApoptosis is an essential physiological process that controls many important biological functions. However, apoptosis signaling in relation to secondary metabolite biosynthesis in plants and fungi remains a mystery. The fungusGanoderma lucidumis a popular herbal medicine worldwide, but the biosynthetic regulation of its active ingredients ...
Bang-Jau You +6 more
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