Current Techniques for the Cultivation of Ganoderma lucidum for the Production of Biomass, Ganoderic Acid and Polysaccharides [PDF]
Ganoderma lucidum is a medicinal mushroom that has been used in the Orient for more than 2000 years. Due to the long time required for basidiocarp formation, attention has recently been given to the use of submerged fermentation for the production of ...
Ricardo Wagner +4 more
doaj +3 more sources
Unveiling triterpenoid superiority in a newly developed Ganoderma lucidum variety through untargeted metabolomics approach [PDF]
The fruiting bodies of Ganoderma lucidum are renowned for their therapeutic properties, primarily due to their triterpenoid content. Variability in G. lucidum strains may influence the composition and abundance of triterpenoids.
Zhibin Pan +5 more
doaj +2 more sources
Enhanced Ganoderic Acids Accumulation and Transcriptional Responses of Biosynthetic Genes in Ganoderma lucidum Fruiting Bodies by Elicitation Supplementation. [PDF]
Ganoderic acids (GAs) are a type of highly oxygenated lanostane-type triterpenoids that are responsible for the pharmacological activities of Ganoderma lucidum.
Meng L +8 more
europepmc +2 more sources
A methyltransferase LaeA regulates ganoderic acid biosynthesis in Ganoderma lingzhi
The methyltransferase LaeA is a global regulator involved in the biosynthesis of secondary metabolites by ascomycete fungi. However, little is known of its regulatory role in basidiomycete fungi.
Qin Luo, Na Li, Jun-Wei Xu
doaj +1 more source
Improved ganoderic acids production in Ganoderma lucidum by wood decaying components. [PDF]
Ganoderma lucidum is a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs).
Hu Y +7 more
europepmc +2 more sources
Hydrogen sulfide maintains mitochondrial homeostasis and regulates ganoderic acids biosynthesis by SQR under heat stress in Ganoderma lucidum. [PDF]
Hydrogen sulfide (H2S) has recently been recognized as an important gaseous transmitter with multiple physiological effects in various species. Previous studies have shown that H2S alleviated heat-induced ganoderic acids (GAs) biosynthesis, an important ...
Shangguan J +9 more
europepmc +2 more sources
Data_Sheet_1_A methyltransferase LaeA regulates ganoderic acid biosynthesis in Ganoderma lingzhi.PDF
The methyltransferase LaeA is a global regulator involved in the biosynthesis of secondary metabolites by ascomycete fungi. However, little is known of its regulatory role in basidiomycete fungi.
Na Li (6550) +2 more
core +1 more source
Lanostane-type triterpenoid ganoderic acids (GAs) possess interesting bioactivities, but their efficient biosynthesis remains challenging. CYP512W2, a promiscuous membrane-anchored cytochrome P450, was recently found to oxidize C7 (or C11) and C15 to ...
Zeqian Du (17425639) +6 more
core +1 more source
A rapid and efficient method is described for the extraction of ganoderic acids from Ganoderma lucidum by means of a small Sep-Pak C/sub 18/ cartridge.
薛文發; Sye, Wen-fa
core +1 more source
Pharmacokinetics of Ganoderic Acids A and F after Oral Administration of Ling Zhi Preparation in Healthy Male Volunteers [PDF]
The objectives of this paper were to evaluate the pharmacokinetics of ganoderic acids A and F after a single oral dose of the water extract of MG2-strain Ling Zhi (MG2FB-WE) and to assess the influence of food on the pharmacokinetics in 12 healthy male ...
Chaichan Sangdee +5 more
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