A methyltransferase LaeA regulates ganoderic acid biosynthesis in Ganoderma lingzhi [PDF]
Frontiers in Microbiology, 2022 The methyltransferase LaeA is a global regulator involved in the biosynthesis of secondary metabolites by ascomycete fungi. However, little is known of its regulatory role in basidiomycete fungi.
Qin Luo, Na Li, Jun-Wei Xu
doaj +4 more sources
Transcriptome analysis of Ganoderma lingzhi (Agaricomycetes) response to Trichoderma hengshanicum infection [PDF]
Frontiers in Microbiology, 2023 Green mold caused by Trichoderma spp. has become one of the most serious diseases which threatening the production of Ganoderma lingzhi. To understand the possible resistance mechanism of the G. lingzhi response to T.
Tiantian Wang +7 more
doaj +4 more sources
Characteristics of the Genome, Transcriptome and Ganoderic Acid of the Medicinal Fungus Ganoderma lingzhi [PDF]
Journal of Fungi, 2022 Ganoderma (Ganodermaceae) is a genus of edible and medicinal mushrooms that create a diverse set of bioactive compounds. Ganoderma lingzhi has been famous in China for more than 2000 years for its medicinal properties.
Qiang Wu +7 more
doaj +2 more sources
The bHLH-zip transcription factor SREBP regulates triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi [PDF]
Communications Biology, 2023 An integration of genomic, DAP-seq, RNA-seq, metabolomic and genetic approaches identifies SREBP as a key transcription factor regulating triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi.
Yong-Nan Liu +9 more
doaj +2 more sources
First Report of Green Mold Disease Caused by Trichoderma hengshanicum on Ganoderma lingzhi [PDF]
Mycobiology, 2020 Ganoderma lingzhi is a well-known source of natural fungal medicines which has been given for the treatment of several diseases. China is one of the major commercial producers of Ganoderma mushroom worldwide. However, with the expansion of the commercial
Mingzhu Cai +4 more
doaj +2 more sources
Improved production of polysaccharides in Ganoderma lingzhi mycelia by plasma mutagenesis and rapid screening of mutated strains through infrared spectroscopy. [PDF]
PLoS ONE, 2018 As a traditional Chinese medicine, Ganoderma lingzhi has attracted increasing attention for both scientific research and medical application. In this work, in order to improve the production of polysaccharides from an original wide-type (WT) strain ...
Yuhan Ma +8 more
doaj +2 more sources
Mass Spectrometry-Based Untargeted Metabolomics and α-Glucosidase Inhibitory Activity of Lingzhi (Ganoderma lingzhi) During the Developmental Stages [PDF]
Molecules, 2019 Lingzhi is a Ganoderma mushroom species which has a wide range of bioactivities. Analysis of the changes in metabolites during the developmental stages of lingzhi is important to understand the underlying mechanism of its biosynthesis, as well as its ...
Dedi Satria +4 more
doaj +2 more sources
Enhanced production of individual ganoderic acids by integrating Vitreoscilla haemoglobin expression and calcium ion induction in liquid static cultures of Ganoderma lingzhi [PDF]
Microbial Biotechnology, 2019 Summary Ganoderic acids produced by Ganoderma exhibit anticancer and antimetastatic activities. A novel approach by combining Vitreoscilla haemoglobin (VHb) expression and calcium ion induction was developed to enhance ganoderic acid (GA) production in ...
Jun‐Wei Xu +5 more
doaj +2 more sources
Effect of different colloidal gold nanomaterials on Ganoderma lingzhi fermentation for production of ganoderma polysaccharide and triterpenoid through macroscopic and microscopic investigation [PDF]
Microbial Cell FactoriesGanoderma lingzhi (G. lingzhi) is a Basidiomycete macrofungus valued for its secondary metabolites with pharmacological activity. To enhance the biosynthesis of secondary metabolites, various exogenous additives have been introduced to fungal ...
Mengqiu Luo +8 more
doaj +2 more sources
The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity [PDF]
BMC BiologyBackground It is generally accepted that nuclear genes in eukaryotes are located independently on chromosomes and expressed in a monocistronic manner. However, accumulating evidence suggests a more complex landscape of gene structure and transcription ...
Lining Wang +9 more
doaj +2 more sources