Results 201 to 210 of about 20,660 (301)

N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting [PDF]

, 2015

core   +1 more source

Neuroinflammation‐Associated Optic Structural–Functional Degeneration in Early Diabetic Optic Neuropathy

Journal of Diabetes, Volume 18, Issue 3, March 2026.
OCT imaging assessments and visual tests, which were validated by pyroptosis of retinal ganglion cells (RGC) and upregulation of NLRP3 and GSDMD expression, established an early structure‐function‐pathology diabetic optic neuropathy (DON) model in high glucose & obesity mice. Early retinal nerve fiber layer (RNFL)/total retinal thickness (TRT) thinning
Jingyuan Zhu, Jinyuan Wang, Haihan Zhang, Mingyang Wang   +3 more
wiley   +1 more source

NLRP3 inflammasome activation in astrocytes restricts SARS-CoV-2 through gasdermin-D-driven IL-1β release. [PDF]

Front Immunol
de Farias IS, Duarte-Barbosa M, Salazar N, Andreata-Santos R, de Lucena VWL, Maricato JT, Gazzinelli RT, Janini LMR, Bortoluci KR.   +8 more
europepmc   +1 more source

P0349 Gasdermin D: A New Inflammatory Biomarker in Assessing Clinical Disease Activity in Crohn’s Disease [PDF]

Osman Çağın Buldukoğlu, Serkan Öcal, Galip Egemen Atar, Başak Bilir Kaya, M D Isik, Gul Aydin Tigli, Serdar Akça, Ferda Akbay Harmandar, Yeşim Çekın, A H Cekin   +9 more
openalex   +1 more source

ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
wiley   +1 more source

Gasdermin D Cleavage and Cytokine Release, Indicative of Pyroptotic Cell Death, Induced by Ophiobolin A in Breast Cancer Cell Lines. [PDF]

Int J Mol Sci
Ranganathan S, Ojo T, Subramanian A, Tobin J, Kornienko A, Boari A, Evidente A, Benton ML, Romo D, Taube JH.   +9 more
europepmc   +1 more source

Supplimentary Mass Spectrometry MALDI data for NatComms: Soluble bacterial lipopeptides suppress gasdermin D-associated IL-33 release in keratinocytes and atopic dermatitis in mice

Reynard Spiess
openalex   +1 more source

D-Mannose Ameliorates Age-Associated Cellular Senescence in the Bladder Urothelium and NLRP3/Gasdermin/IL-1β-Driven Pyroptotic Epithelial Cell Shedding

, 2022
Chetanchandra S. Joshi, Arnold Salazar, Caihong Wang, Marianne M. Ligon, Rayvanth R. Chappidi, Bisiayo Fashemi, Paul A. Felder, Amy Mora, Sandra L. Grimm, Cristian Coarfa, Indira U. Mysorekar   +10 more
openalex   +1 more source

Honokiol and Magnolol Exert an Anti‐Inflammatory Effect by Inhibiting JAK2/STAT3/IL17 Signalling in a Rat Model of Ulcerative Colitis: A Combination of Bioinformatics and Experimental Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ulcerative colitis (UC) is a chronic, inflammatory bowel disease with limited clinical treatment. Traditional Chinese medicinal ingredients honokiol and magnolol have potential anti‐inflammatory and gastrointestinal protective effects. However, their anti‐inflammatory potential has not been investigated in UC.
Zhaoxu Cai, Shaojun Lu, Jingan Chen, Xiaoshan Yang, Junlin Lu, Changwen Feng   +5 more
wiley   +1 more source

Cleavage of cellular substrate porcine gasdermin D by porcine torovirus 3C-like protease induces pyroptosis. [PDF]

Virulence
Pan D, Liu XE, Hong X, Liu Y, Yin PF, Zeng JW, Lv Q, Du EZ, Fan W, Yang YL, Shi F, Wang B, Dong B, Huang YW.   +13 more
europepmc   +1 more source