Results 121 to 130 of about 488,720 (294)

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

Lemon Balm as a Source of Potentially Bioaccessible Rosmarinic Acid: The Effect of Herbal Preparation Type, Dosage, and Digestion-Related Factors

Applied Sciences
This study aimed to evaluate how the dosage, type of herbal preparation (plant material, dry extract, or isolated compound), along with simulated digestion-related factors, i.e., digestion stage (gastric vs.
Łukasz Sęczyk
doaj   +1 more source

Influence of In Vitro Gastric Digestion of Olive Leaf Extracts on Their Bioactive Properties against H. pylori. [PDF]

Foods, 2022
Villalva M, Silvan JM, Guerrero-Hurtado E, Gutierrez-Docio A, Navarro Del Hierro J, Alarcón-Cavero T, Prodanov M, Martin D, Martinez-Rodriguez AJ.   +8 more
europepmc   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

Study on the physicochemical properties and antioxidant capacity of fish maw digestive juices from Pangasianodon hypophthalmus

Shipin yu jixie
ObjectiveThis study aimed to investigate the impact of digestion time on the digestibility, physicochemical properties, and antioxidant activity of Pangasianodon hypophthalmus fish maw.MethodsIn vitro digestion was performed with simulated gastric fluid ...
FENG Rui, HUANG Darong, ZHONG Biluan, ZHANG Yu, LIANG Jiehua, TANG Xiaoshu, CHEN Xuemei, TIAN Jianxin   +7 more
doaj   +1 more source

Dynamic gastric digestion of a commercial whey protein concentrate

, 2017
Part of this work was presented as a poster at the 29th Effost International Conference, Athens, Greece, 2015.[Background]: A dynamic gastrointestinal simulator, simgi, has been applied to assess the gastric digestion of a whey protein concentrate ...
Del Barrio, R., Lourdes Amigo, Recio, Isidra, Isidra Recio, Miralles, Beatriz, Roberto del Barrio, Cueva, Carolina, Beatriz Miralles, Carolina Cueva, Amigo, Lourdes   +9 more
core   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Effect of in vitro gastric and duodenal digestion on the allergenicity of grape lipid transfer protein

, 2006
Background: Severe grape allergy has been linked to lipid transfer protein (LTP) sensitization. LTPs are known to be resistant to pepsin digestion, although the effect of gastroduodenal digestion on its allergenicity has not been reported.
Mills, C., Vassilopoulou, E., van Ree, R., Saxoni-Papageorgiou, P., Papadopoulos, N.G., Rigby, N., Akkerdaas, J., Moreno, F.J., Tassios, I., Zuidmeer, L.   +9 more
core   +2 more sources

Fat Oxidation of Fatty Fish vs. Meat Meal Diets Under in vitro Standardized Semi-Dynamic Gastric Digestion. [PDF]

Front Nutr, 2022
Harahap IA, Sobral MMC, Casal S, Pinho SCM, Faria MA, Suliburska J, Ferreira IMPLVO.   +6 more
europepmc   +1 more source

Gastric digestion of cow and goat milk: Peptides derived from simulated conditions of infant digestion

, 2019
Infant formula products are predominantly manufactured using cow milk protein; goat milk also provides a suitable protein source. In this study, we directly compared cow and goat milk protein digestion using pH and enzyme conditions to simulate infant ...
Alison Hodgkinson (15394178), Olivia Wallace (13947817), Grant Smolenski (2511337), Colin Prosser (15395060)   +3 more
core