Results 131 to 140 of about 488,720 (294)

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Effects of Inoculating Autochthonous Starter Cultures on Changes of N-Nitrosamines and Their Precursors in Chinese Traditional Fermented Fish during In Vitro Human Digestion

Foods
The objective of this research was to investigate the impact of inoculating autochthonous starter cultures on the alterations in microorganisms, biogenic amines, nitrite, and N-nitrosamines in Chinese traditional fermented fish products (CTFPs) during in
Han Li, Qian Li, Qi Wang, Jiwang Chen, Wenshui Xia, E Liao   +5 more
doaj   +1 more source

DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer

Advanced Science, EarlyView.
Traditional diagnosis may miss positive LNM cases, and pathologists face a workload; therefore, we develop DeepLNM, a multimodal model that predicts lymph node metastasis in colorectal cancer from H&E WSIs, CT images, and text. DeepLNM is robust across internal, external, and prospective cohorts and, in a user study, improves diagnostic accuracy while ...
Zhengyu Zhang, Chengyu Lu, Zhen Wang, Zhijian Cen, Yangshu Zhou, Danyi Li, Qi Xie, Bingbing Li, Shujing Guo, Zhijun Gan, Er‐ran Zhu, Jinbang Li, Aihetaimu Aimaier, Rui Mao, Weihao Qiu, Chenglong Zhao, Ying Tan, Xiaolin Liu, Huiting Ma, Tiansu Geng, Peiyue Wu, Huijun Du, Yu Wang, Yueping Liu, Li Liang   +24 more
wiley   +1 more source

A miniaturised semi-dynamic in-vitro model of human digestion

Scientific Reports
Reliable in-vitro digestion models that are able to successfully replicate the conditions found in the human gastrointestinal tract are key to assess the fate and efficiency of new formulations aimed for oral consumption. However, current in-vitro models
Victor Calero, Patrícia M. Rodrigues, Tiago Dias, Alar Ainla, Adriana Vilaça, Lorenzo Pastrana, Miguel Xavier, Catarina Gonçalves   +7 more
doaj   +1 more source

Structural Property, Immunoreactivity and Gastric Digestion Characteristics of Glycated Parvalbumin from Mandarin Fish (Siniperca chuaisi) during Microwave-Assisted Maillard Reaction. [PDF]

Foods, 2022
Tai J, Qiao D, Huang X, Hu H, Li W, Liang X, Zhang F, Lu Y, Zhang H.   +8 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

APPARENT BIOACCESSIBILITY OF PHENOLIC COMPOUNDS AND LYCOPENE FROM TOMATO POMACE DURING STATIC IN VITRO DIGESTION

Studia Universitatis Babes-Bolyai Chemia
Tomato pomace, a major by-product of industrial tomato processing composed mainly of peels and seeds, represents a valuable source of bioactive compounds with potential nutraceutical applications.
Vanda Liliana BĂBĂLĂU FUSS, Oana CADAR, Ancuța IVAN, Cristina BĂLGĂRĂDEAN, Lucian CUIBUS, Anca BECZE   +5 more
doaj   +1 more source

Gastric Digestion of Milk Proteins in Adult and Elderly: Effect of High-Pressure Processing. [PDF]

Foods, 2021
Aalaei K, Khakimov B, De Gobba C, Ahrné L.   +3 more
europepmc   +1 more source

Gastric digestion of cow and goat milk: Impact of infant and young child in vitro digestion conditions

, 2017
Many infants and young children are fed nutritional milk formulas. Although products are commonly based on cow milk, goat milk provides an alternative.
Alison Hodgkinson (15394178), Olivia Wallace (13947817), Marita Broadhurst (15394994), Irina Boggs (15395825), Colin Prosser (15395060)   +4 more
core  

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source