Results 131 to 140 of about 70,974 (289)

A miniaturised semi-dynamic in-vitro model of human digestion

Scientific Reports
Reliable in-vitro digestion models that are able to successfully replicate the conditions found in the human gastrointestinal tract are key to assess the fate and efficiency of new formulations aimed for oral consumption. However, current in-vitro models
Victor Calero, Patrícia M. Rodrigues, Tiago Dias, Alar Ainla, Adriana Vilaça, Lorenzo Pastrana, Miguel Xavier, Catarina Gonçalves   +7 more
doaj   +1 more source

APPARENT BIOACCESSIBILITY OF PHENOLIC COMPOUNDS AND LYCOPENE FROM TOMATO POMACE DURING STATIC IN VITRO DIGESTION

Studia Universitatis Babes-Bolyai Chemia
Tomato pomace, a major by-product of industrial tomato processing composed mainly of peels and seeds, represents a valuable source of bioactive compounds with potential nutraceutical applications.
Vanda Liliana BĂBĂLĂU FUSS, Oana CADAR, Ancuța IVAN, Cristina BĂLGĂRĂDEAN, Lucian CUIBUS, Anca BECZE   +5 more
doaj   +1 more source

Structural Property, Immunoreactivity and Gastric Digestion Characteristics of Glycated Parvalbumin from Mandarin Fish (Siniperca chuaisi) during Microwave-Assisted Maillard Reaction. [PDF]

Foods, 2022
Tai J, Qiao D, Huang X, Hu H, Li W, Liang X, Zhang F, Lu Y, Zhang H.   +8 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

Evaluation of freeze-dried phenolic extract from cashew apple by-product: Physical properties, in vitro gastric digestion and chemometric analysis of the powders. [PDF]

Food Chem (Oxf), 2022
de Souza Lima AC, Filho EGA, Sampaio LMF, Pontes CM, Afonso MRA, Ribeiro PRV, Canuto KM, Eça KS, de Siqueira Oliveira L.   +8 more
europepmc   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Gastric Digestion of Milk Proteins in Adult and Elderly: Effect of High-Pressure Processing. [PDF]

Foods, 2021
Aalaei K, Khakimov B, De Gobba C, Ahrné L.   +3 more
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Bitter Peptides YFYPEL, VAPFPEVF, and YQEPVLGPVRGPFPIIV, Released during Gastric Digestion of Casein, Stimulate Mechanisms of Gastric Acid Secretion via Bitter Taste Receptors TAS2R16 and TAS2R38. [PDF]

J Agric Food Chem, 2022
Richter P, Sebald K, Fischer K, Behrens M, Schnieke A, Somoza V.   +5 more
europepmc   +1 more source