Results 61 to 70 of about 39,803 (247)

Rikkunshito prevents blood glucose intolerance in rats undergoing distal pancreatectomy

Endocrine and Metabolic Science
Background: After pancreatic surgery, impaired glucose tolerance may occur as a consequence of surgery, which has the potential to predispose a patient to diabetes.
Hiroshi Kono, Hidetake Amemiya, Naohiro Hosomura, Daisuke Ichikawa   +3 more
doaj   +1 more source

Gastric Inhibitory Polypeptide Increases Mesenteric Blood Flow

Experimental Biology and Medicine, 1978
SummaryGastric inhibitory polypeptide (GIP) induces dose-dependent increases in superior mesenteric blood flow in the anesthetized cat. There was no concommitant change in systemic arterial pressure or in femoral blood flow indicating a specific decrease in mesenteric vascular resistance.
J W, Fara, A M, Salazar
openaire   +2 more sources

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +2 more sources

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Tirzepatide, GIP(1-42) and GIP(1-30) display unique signaling profiles at two common GIP receptor variants, E354 and Q354

Frontiers in Pharmacology
Type 2 diabetes (T2D) and obesity are prevalent metabolic disorders affecting millions of individuals worldwide. A new effective therapeutic drug called tirzepatide for the treatment of obesity and T2D is a dual agonist of the GIP receptor and GLP-1 ...
Tayla A. Rees, Tayla A. Rees, Tayla A. Rees, Benjamin J. Buttle, Zoe Tasma, Zoe Tasma, Sung-Hyun Yang, Paul W. R. Harris, Paul W. R. Harris, Paul W. R. Harris, Christopher S. Walker, Christopher S. Walker   +11 more
doaj   +1 more source

Entero-insular axis in children with simple obesity [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2009
Introduction: The entero-insular axis plays an important role in generation ofsatiety signal. Thus, disturbances in this axis can influence the path to a simple obesity.
Jerzy Starzyk, Krystyna Sztefko, Przemysław J. Tomasik   +2 more
doaj  

Gastric Inhibitory Polypeptide Secretion After Radical Pancreatoduodenectomy

Annals of Surgery, 1984
To elucidate the role of gastric inhibitory polypeptide (GIP) in the alteration of insulin secretion following pancreatoduodenal resection, in which the main sources of GIP are removed, plasma levels of GIP were measured for 180 minutes after oral glucose administration, both before and after radical pancreatoduodenectomy in nine patients with ...
M, Miyata, K, Nakao, Y, Tanaka, T, Sakamoto, M, Hamaji, H, Taketani, Y, Kawashima   +6 more
openaire   +3 more sources

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Influence of dietary intake and eating patterns on reactive hypoglycemic events in patients postesophagectomy: A prospective observational study using continuous glucose monitoring

Nutrition in Clinical Practice, EarlyView.
Abstract Background Esophagectomy causes anatomical changes that can lead to rapid food transit and reactive hypoglycemia (RH). Patients are advised on eating patterns postesophagectomy to prevent RH, but its true incidence and the impact of dietary recommendations remain under‐researched.
Rachel O'Kelly, Elaine Quigley, Katie Byrne, Mistura A. Kareem, Niamh Ni Mhaoinigh, Paul Healy, Michelle Fanning, John V. Reynolds, Claire L. Donohoe, Suzanne L. Doyle   +9 more
wiley   +1 more source

The enteric nervous system : new developments and emerging concepts [PDF]

, 2011
The enteric nervous system (ENS) is an integrative neuronal network, organized in two ganglionated plexuses, myenteric and submucosal, composed of neurons and enteric glial cells, controlling the activity of the smooth muscle of the gut, mucosal ...
Garzia Zizzo, Maria, Mastropaolo, Mariangela, Serio, Rosa   +2 more
core   +2 more sources