Results 71 to 80 of about 64,020 (335)

Acute effects of elevated NEFA on vascular function: a comparison of SFA and MUFA [PDF]

, 2010
There is emerging evidence to show that high levels of NEFA contribute to endothelial dysfunction and impaired insulin sensitivity. However, the impact of NEFA composition remains unclear.
Abby K. Thompson, Beysen, Christine M. Williams, Hogikyan, John Wright, Katie J. Newens, Kim G. Jackson, Wang, Xiao-Yun, Zampelas   +9 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu, Guillaume Mabilleau, Iepsen, Iepsen, Marie Pereira   +4 more
core   +5 more sources

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Genome-wide interaction study with body mass index identifies and as genetic modulators of metabolic dysfunction-associated steatotic liver disease [PDF]

Clinical and Molecular Hepatology
Background/Aims Metabolic dysfunction-associated steatotic liver disease (MASLD) may progress to liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma. So far, genome-wide association studies explain a small fraction of MASLD heritability.
Oveis Jamialahmadi, Endrina Mujica, Lowri Morris, Rosellina Margherita Mancina, Ester Ciociola, Sami F. Qadri, Samantha Maurotti, Francesco Malvestiti, Ruifang Li-Gao, Luisa Ronzoni, Federica Tavaglione, Hannah Maude, Amin Allalou, Anastasia Emmanouilidou, Umberto Vespasiani-Gentilucci, Frits Richard Rosendaal, Hannele Yki-Järvinen, Inês Cebola, Luca Valenti, Marcel den Hoed, Stefano Romeo   +20 more
doaj   +1 more source

The Role of cAMP in Beta Cell Stimulus–Secretion and Intercellular Coupling

Cells, 2021
Pancreatic beta cells secrete insulin in response to stimulation with glucose and other nutrients, and impaired insulin secretion plays a central role in development of diabetes mellitus.
Andraž Stožer, Eva Paradiž Leitgeb, Viljem Pohorec, Jurij Dolenšek, Lidija Križančić Bombek, Marko Gosak, Maša Skelin Klemen   +6 more
doaj   +1 more source

Mechanisms for the encapsulation of lipophilic polyphenols in protein/polysaccharide complexes or conjugates‐based nanocarriers

Food Biomacromolecules, EarlyView.
Abstract Traditional heat processing technology restricts the direct development of lipophilic polyphenols (LPPs)‐fortified foods. For achieving a balance between high retention of biological activity and optimal edible quality, encapsulation of LPPs by proteins/polysaccharide complexes or conjugates‐based nanocarriers (PPCCNs) as food ingredients has ...
Yuanhong Chen, Jiangfeng Xu, Jiaying Tang, Qing Zhang   +3 more
wiley   +1 more source

Finerenone attenuates downregulation of the kidney GLP-1 receptor and glucagon receptor and cardiac GIP receptor in mice with comorbid diabetes

Diabetology & Metabolic Syndrome
Background Several new treatments have recently been shown to have heart and kidney protective benefits in people with diabetes. Because these treatments were developed in parallel, it is unclear how the different molecular pathways affected by the ...
Duc Tin Tran, Emily S. H. Yeung, Lisa Y. Q. Hong, Harmandeep Kaur, Suzanne L. Advani, Youan Liu, Madiha Zahra Syeda, Sri Nagarjun Batchu, Andrew Advani   +8 more
doaj   +1 more source

Advantages of incretin-based treatment in management of type 2 diabetes [PDF]

, 2017
The risk of hypoglycemia with sulfonylureas is higher in the presence of diabetic nephropathy. Selective DPP-4 inhibitors lead to physiologic increases in the incretins GLP-1 and gastric inhibitory polypeptide and preferable for the management of ...
Abbas, Ahmad L., Fadieieva, Hanna Anatoliivna, Фадеева, Анна Анатольевна, Фадєєва, Ганна Анатоліївна   +3 more
core  

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq, Sajad Ahmad Mir, Zahida Naseem   +2 more
wiley   +1 more source