Results 1 to 10 of about 65,820 (233)
NF-kappaB mediated transcriptional repression of acid modifying hormone gastrin. [PDF]
PLoS ONE, 2013 Helicobacter pylori is a major pathogen associated with the development of gastroduodenal diseases. It has been reported that H. pylori induced pro-inflammatory cytokine IL1B is one of the various modulators of acid secretion in the gut.
Dipanjana Datta De +3 more
doaj +6 more sources
Preoperative Localization of a Gastrin-Secreting Tumour by Total Body Imaging with 111Indium-Labelled Pentatreotide [PDF]
Canadian Journal of Gastroenterology, 1994 A 41-year-old female presented with persistent diarrhea, and was diagnosed with Zollinger-Ellison syndrome when her gastrin level was greater than 3000 ng/L.
Humera Ali +3 more
doaj +2 more sources
Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. [PDF]
PLoS ONE, 2013 Neurogenin3(+) (Ngn3(+)) progenitor cells in the developing pancreas give rise to five endocrine cell types secreting insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin.
Yaron Suissa +12 more
doaj +1 more source
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis
Molecular Medicine, 2021 Background It is known that increased gastrin concentration is negatively correlated with cardiovascular mortality, and plasma gastrin levels are increased in patients after myocardial infarction (MI).
Jinjuan Fu +5 more
doaj +1 more source
Interleukin-1β Suppresses Gastrin via Primary Cilia and Induces Antral HyperplasiaSummary
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Helicobacter pylori infection in humans typically begins with colonization of the gastric antrum. The initial Th1 response occasionally coincides with an increase in gastrin secretion.
Lin Ding +3 more
doaj +1 more source
NR4A2 is regulated by gastrin and influences cellular responses of gastric adenocarcinoma cells. [PDF]
PLoS ONE, 2013 The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the adenocarcinoma cell lines AR42J ...
Kristine Misund +9 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Ischemic/reperfusion (I/R) injury is the primary cause of acute kidney injury (AKI). Gastrin, a gastrointestinal hormone, is involved in the regulation of kidney function of sodium excretion. However, whether gastrin has an effect on kidney I/R injury is
Chao Liu +23 more
doaj +1 more source
F1000Research, 2013 The role of the peptide hormone gastrin in stimulating gastric acid secretion is well established. Mature amidated gastrin is processed from larger peptide precursor forms.
Ian LP Beales
doaj +1 more source
Scientific Reports, 2021 Acute myocardial infarction (MI) is one of the leading causes of death in humans. Our previous studies showed that gastrin alleviated acute myocardial ischaemia–reperfusion injury.
Rui Wang +14 more
doaj +1 more source
Tumor Biology, 2017 Nerve fibers and neurotransmitters have increasingly been shown to have a role in tumor progression. Gastrin-releasing peptide is a neuropeptide linked to tumor aggressiveness, acting as an autocrine tumor growth factor by binding to its receptor ...
Natália Jaeger +4 more
doaj +1 more source