Results 11 to 20 of about 29,877 (187)
Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series. [PDF]
DEN OpenType I gastric neuroendocrine tumors (T1‑GNETs) often present as multiple lesions, complicating treatment. This retrospective case series study evaluates antrectomy outcomes in eight patients with persistent multiple T1‑GNETs during 2005–2023. Following antrectomy, tumor regression was observed in two patients and complete disappearance in six, with ...
Morita Y +9 more
europepmc +2 more sources
Gastrin, gastrin receptors and colorectal carcinoma [PDF]
Gut, 1998 The possibility that gastrin may play a role in the development of colorectal carcinoma has aroused considerable interest over the past decade. In early reports some colorectal carcinomas and colorectal carcinoma cell lines were shown to produce gastrin,1 to express gastrin receptors,2 and to respond mitogenically to exogenous gastrin.2 The most ...
G S, Baldwin, A, Shulkes
openaire +2 more sources
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
The Lancet, 1965 The Lancet 285 (1965) 816-816.
University of Florida, Gainesville, United States. ( host institution ) +1 more
+7 more sources
Gut, 1972 Gastrin release in the basal state and following a standard protein meal has been estimated in patients after partial gastrectomy, partial gastrectomy with truncal vagotomy, and total gastrectomy. Following partial gastrectomy, gastrin rose from 8 ± 0·8 to 20 ± 3·8 pg/ml with a protein meal.
M G, Korman, C, Soveny, J, Hansky
openaire +2 more sources
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. [PDF]
PLoS ONE, 2014 Salt-inducible kinase 1 (SIK1/Snf1lk) belongs to the AMP-activated protein kinase (AMPK) family of kinases, all of which play major roles in regulating metabolism and cell growth.
Linn-Karina M Selvik +8 more
doaj +1 more source
IL1B induced Smad 7 negatively regulates gastrin expression. [PDF]
PLoS ONE, 2011 BACKGROUND: Helicobacter pylori elicited IL1B is one of the various modulators responsible for perturbation of acid secretion in gut. We have earlier reported that IL1B activated NFkB downregulates gastrin, a major modulator of acid secretion.
Dipanjana Datta De +6 more
doaj +1 more source
Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.
PLoS ONE, 2013 Neurogenin3(+) (Ngn3(+)) progenitor cells in the developing pancreas give rise to five endocrine cell types secreting insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin.
Yaron Suissa +12 more
doaj +1 more source
Clinical Significance of Serum Gastrin Levels in Patients with Colorectal Cancer
The International Journal of Biological Markers, 2004 Aims An association between elevated serum gastrin levels and the presence of human colorectal cancer has been reported, and gastrin has been shown to stimulate the growth of experimentally induced colon neoplasia.
A. Tocchi +7 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Ischemia/reperfusion injury (IRI) is one of the most predominant complications of ischemic heart disease. Gastrin has emerged as a regulator of cardiovascular function, playing a key protective role in hypoxia.
Xiaoli Yang +13 more
doaj +1 more source