Results 31 to 40 of about 40,702 (217)

Radioimmunoassay of gastrin

open access: yesGastroenterology, 1970
Summary A highly specific radioimmunoassay for endogenous human plasma gastrin was developed using guinea pig antisera to crude porcine gastrin. Highly purified 125 I-porcine gastrin I, further purified on starch gel electrophoresis after labeling, was employed as tracer, and an anionic exchange resin was used to separate bound and free labeled ...
R S, Yalow, S A, Berson
openaire   +2 more sources

Clinical application of serological gastric biopsy in the screening of gastric precancerous disease

open access: yesZhongguo linchuang yanjiu, 2023
Objective To analyze the correlation between gastric mucosa serological biopsy [serum pepsinogen Ⅰ(PGⅠ), pepsinogen Ⅱ(PGⅡ), ratio of PGⅠ/PGⅡ(PGR), gastrin-17 and helicobacter pyloriantibody(HP-IgG)] and histological gastritis evaluation criteria (OLGA ...
DONG Wen-zhu*, LIANG Yue, ZHAO Qi, YU Hai-tao, LI Dong, CHEN Yan, WANG Qun-ying
doaj   +1 more source

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Helicobacter pylori is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, H.
Niluka Gunawardhana   +14 more
doaj   +1 more source

Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes

open access: yesFrontiers in Endocrinology, 2020
The structurally-related peptides, gastrin and cholecystokinin (CCK), were originally discovered as humoral stimulants of gastric acid secretion and pancreatic enzyme release, respectively.
Qiang Zeng   +3 more
doaj   +1 more source

Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

open access: yesBMC Cancer, 2018
Background Gastrin is an important gastrointestinal hormone produced primarily by G-cells in the antrum of the stomach. It normally regulates gastric acid secretion and is implicated in a number of human disease states, but how its function affects ...
Li-Li Meng   +7 more
doaj   +1 more source

Effect of Dexmedetomidine-Assisted Intravenous Anesthesia on Gastrointestinal Motility in Colon Cancer Patients After Open Colectomy

open access: yesFrontiers in Surgery, 2022
BackgroundTo explore the effect of dexmedetomidine (Dex)-assisted intravenous anesthesia on gastrointestinal motility in patients with colon cancer (CC) after open colectomy.MethodsA total of 102 patients with CC, undergoing open colectomy in our ...
Chaopeng Ou   +4 more
doaj   +1 more source

Gastrin signaling in cardiovascular pathophysiology: From molecular crosstalk to clinical implications

open access: yesClinical and Experimental Hypertension
As a gastrointestinal hormone, gastrin stimulates gastric acid secretion and intestinal mucosal nutrition. Evidence links it closely to coronary heart disease, ischemia‒reperfusion injury and hypertension.
Chunmei Xu   +4 more
doaj   +1 more source

Therapeutic effects of Bombax ceiba flower aqueous extracts against loperamide-induced constipation in mice

open access: yesPharmaceutical Biology, 2023
Context Bombax ceiba Linnaeus (Bombacaceae) is known as silk cotton tree, the flowers of which are used in many medicinal applications.Objective To investigate the therapeutic effect of B.
Liuping Wang   +6 more
doaj   +1 more source

Gastrin and Gastric Cancer [PDF]

open access: yesFrontiers in Endocrinology, 2017
Gastric cancer although occurring in reduced frequency is still an important disease, partly because of the bad prognosis when occurring in western countries. This decline in occurrence may mainly be due to the reduced prevalence of Helicobacter pylori (Hp) infection, which is the most important cause of gastric cancer.
Waldum, Helge   +2 more
openaire   +3 more sources

Effect of gastric acid-suppressive therapy and biological variation of serum gastrin concentrations in dogs with chronic enteropathies

open access: yesBMC Veterinary Research, 2017
Background Serum gastrin concentration can help diagnose gastrinomas in dogs if >3–10× the upper reference limit (URL), but antisecretory therapy and other conditions can also cause hypergastrinemia.
Romy M. Heilmann   +5 more
doaj   +1 more source

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