Results 51 to 60 of about 29,877 (187)

Hypergastrinemia in Children : A Case Report

open access: yesArchives of Pediatric Gastroenterology, Hepatology, and Nutrition, 2022
Gastrin is an important hormone in the gastrointestinal system that promotes gastric acid secretion. Gastrin hormone is produced by the G-cells in the antrum of the stomach.
Edbert Wielim   +2 more
doaj   +1 more source

The Search for Submammalian Gastrins: The Identification of Amphibian Gastrin

open access: yesExperimental Biology and Medicine, 1976
SummaryExtracts of the digestive tracts of three amphibian species were examined by radioimmunoassay for gastrin-like materials. Gastrin was detected in all three species of amphibia examined. In R. cates-beiana and R. pipiens the largest tissue concentrations of gastrin were found in the antrum, followed by the duodenum and pancreas, respectively, in ...
R G, Gibson   +3 more
openaire   +2 more sources

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin   +10 more
wiley   +1 more source

Gastric duplication cyst causing hypergastrinemia in an infant

open access: yesJPGN Reports, EarlyView.
Abstract Gastric duplication cysts are rare congenital anomalies, with fewer than 10% occurring in the stomach. We report a 14‐month‐old girl presenting with failure to thrive, recurrent emesis, hematemesis, and severe duodenitis with ulceration. Laboratory evaluation revealed marked hypergastrinemia (1781 pg/mL), and initial imaging was unrevealing ...
Nathan Bryan, Ian Leibowitz
wiley   +1 more source

Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background To test the hypothesis that activated extracellular signal-regulated kinase (ERK) regulates P65-miR23a/27a/24 axis in gastric cancer (GC) and the ERK-P65-miR23a/27a/24 axis plays an important role in the development of GC, and to evaluate the ...
Li-Dong Zu   +8 more
doaj   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

Recharacterization data for a geriatric gastrin polycolonal antibody

open access: yesData in Brief, 2019
Radioimmunoassay data on the recharacterization of a gastrin polycolonal antibody first generated in 1973 is presented. The data include specificity, effect of matrix, and the establishment of a reference range for circulating fasting gastrin ...
Steven Dodd   +3 more
doaj   +1 more source

Serum Gastrin and Pepsinogen Levels after Administration of Acid Secretion Inhibitors for Ulcers due to Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer

open access: yesGastroenterology Research and Practice, 2022
Acid secretion inhibitors, such as proton pump inhibitors (PPIs) and potassium competitive acid blockers (PCABs), are used to treat ulcers after endoscopic submucosal dissection (ESD) for early gastric cancer.
Maidina Abuduwaili   +7 more
doaj   +1 more source

Perioperative Risks of Concurrent Pancreatic and Hepatic Resections for Neuroendocrine Tumors

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Pancreatic neuroendocrine tumors (pNETs) account for 1%–2% of pancreatic tumors, with an increasing incidence. The safety of concurrent pancreas‐liver resections remains uncertain. This study evaluated the national outcomes of concurrent pancreatectomy and liver‐directed surgery for pNETs. Methods ACS‐NSQIP (2019–2023)
Amir Ebadinejad   +4 more
wiley   +1 more source

Premises for Cholecystokinin and Gastrin Peptides in Diabetes Therapy

open access: yesClinical Medicine Insights: Endocrinology and Diabetes, 2019
Gastrin and cholecystokinin (CCK) are classical gastrointestinal peptide hormones. Their biogenesis, structures, and intestinal secretory patterns are well-known with the striking feature that their receptor-bound ‘active sites’ are highly homologous and
Jens F Rehfeld
doaj   +1 more source

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