Results 81 to 90 of about 6,216 (159)

First in-human radiation dosimetry of the gastrin-releasing peptide (GRP) receptor antagonist 68Ga-NODAGA-MJ9

EJNMMI Research, 2018
Background Gastrin-releasing peptide receptor antagonists have promise in theranostics of several highly incident tumours, including prostate and breast.
Silvano Gnesin, Francesco Cicone, Periklis Mitsakis, Axel Van der Gucht, Sébastien Baechler, Raymond Miralbell, Valentina Garibotto, Thomas Zilli, John O. Prior   +8 more
doaj   +1 more source

Gastrin-releasing peptide receptor-targeted gadolinium oxide-based multifunctional nanoparticles for dual magnetic resonance/fluorescent molecular imaging of prostate cancer

International Journal of Nanomedicine, 2017
Danting Cui,1 Xiaodan Lu,1 Chenggong Yan,1 Xiang Liu,1 Meirong Hou,1 Qi Xia,2 Yikai Xu,1 Ruiyuan Liu2,3 1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 2School of ...
Cui DT, Lu XD, Yan CG, Liu X, Hou MR, Xia Q, Xu YK, Liu RY   +7 more
doaj  

Advances in the Research of Radioactive Molecular Probes Targeting GRPR

Journal of Isotopes
Gastrin-releasing peptide receptor (GRPR) is highly expressed in prostate cancer，breast cancer，and gastrointestinal tumors，but lowly expressed in normal tissues and organs，providing an ideal target for molecular imaging.
Minyi ZHANG, Xiangyu QIN, Xiaoyu FAN, Baoqi ZHANg, Kai WEN, Xueqin XIANG   +5 more
doaj   +1 more source

Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch

Neurobiology of Disease
Chronic itch remains a clinically challenging condition with limited therapeutic efficacy, posing a significant burden on patients' quality of life. Despite its prevalence, the underlying neural mechanisms remain poorly understood.
Danqing Dai, Zongxi Li, Tiantian Zhao, Zhen Li, Yali Tang, Xiujuan Li, Xiao-Fei Gao, Lize Xiong   +7 more
doaj   +1 more source

Gastrin-Releasing Peptide Receptor [PDF]

, 2020
openaire   +1 more source

Synaptic circuits involving gastrin-releasing peptide receptor-expressing neurons in the dorsal horn of the mouse spinal cord. [PDF]

Front Mol Neurosci, 2023
Quillet R, Gutierrez-Mecinas M, Polgár E, Dickie AC, Boyle KA, Watanabe M, Todd AJ.   +6 more
europepmc   +1 more source

The effects of novel macrocyclic chelates on the targeting properties of the ⁶⁸Ga-labeled Gastrin releasing peptide receptor antagonist RM2. [PDF]

EJNMMI Res, 2023
Wang Y, Yuan H, Tang S, Liu Y, Cai P, Liu N, Chen Y, Zhou Z.   +7 more
europepmc   +1 more source

Heterogeneity between VIP and GRP neurons underlies AVP receptor signaling in the mouse suprachiasmatic nucleus

Communications Biology
Understanding the network topology of a cluster of diverse neurons acting in concert requires a detailed expression map of ligand–receptor pairs involved in cell–cell communication.
Huihua Zhou, Daichi Moriyasu, Sui-Wen Hsiao, Yoshiaki Yamaguchi, Morio Azuma, Taka-aki Koshimizu, Keiichi Itoi, Kenji Sakimura, William J. Schwartz, Hitoshi Okamura, Emi Hasegawa, Masao Doi   +11 more
doaj   +1 more source

The contribution of endocytic mediators to itch transmission

Frontiers in Molecular Neuroscience
IntroductionChronic itch is a major burden, impacting the quality of life for one in four adults, and is closely associated with increased levels of anxiety, depression, and suicide.
Marcella de A. Ferreira, Marcella de A. Ferreira, Raquel Tonello, Raquel Tonello, Paz Duran, Paz Duran, Kai Trevett, Kai Trevett, Dane D. Jensen, Dane D. Jensen, Dane D. Jensen   +10 more
doaj   +1 more source

NOTA and NODAGA Radionuclide Complexing Agents: Versatile Approaches for Advancements in Radiochemistry

Molecules
Effective molecular imaging and targeted cancer therapy rely on receptor-specific targeted delivery systems that are both metabolically stable and kinetically inert for optimal in vivo performance.
Claudia G. Chambers, Jing Wang, Tamer M. Sakr, Yubin Miao, Charles J. Smith   +4 more
doaj   +1 more source