Background Ischemia/reperfusion injury (IRI) is one of the most predominant complications of ischemic heart disease. Gastrin has emerged as a regulator of cardiovascular function, playing a key protective role in hypoxia.
Xiaoli Yang+13 more
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Gastrin and cholecystokinin (CCK) are hormones released from endocrine cells in the antral stomach (gastrin), the duodenum, and the jejunum (CCK). Recent reports, based on secretion experiments in an enteroendocrine cell line (NCI‐H716) and gastrin ...
Ida M. Modvig+4 more
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The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates [PDF]
Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: (1) gonadotropin-inhibitory hormone (GnIH), (2) neuropeptide FF (NPFF), (3) pyroglutamylated RFamide peptide (QRFP), (4) prolactin-releasing peptide (
Elphick, MR, Mirabeau, O
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Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes
The structurally-related peptides, gastrin and cholecystokinin (CCK), were originally discovered as humoral stimulants of gastric acid secretion and pancreatic enzyme release, respectively.
Qiang Zeng+3 more
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Spinal neurons that contain gastrin-releasing peptide seldom express Fos or phosphorylate extracellular signal-regulated kinases in response to intradermal chloroquine [PDF]
Background: Gastrin-releasing peptide (GRP) is thought to play a role in the itch evoked by intradermal injection of chloroquine. Although some early studies suggested that GRP was expressed in pruriceptive primary afferents, it is now thought that GRP ...
Bell, Andrew M.+3 more
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IL1B induced Smad 7 negatively regulates gastrin expression. [PDF]
BACKGROUND: Helicobacter pylori elicited IL1B is one of the various modulators responsible for perturbation of acid secretion in gut. We have earlier reported that IL1B activated NFkB downregulates gastrin, a major modulator of acid secretion.
Dipanjana Datta De+6 more
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Solitary pulmonary nodules prediction for lung cancer patients using nomogram and machine learning [PDF]
Lung cancer(LC) is a type of malignant neoplasm that originates in the bronchial mucosa or glands.As a clinically common nodule,solitary pulmonary nodules(SPNs) have a significantly higher probability of malignancy when they are larger than 8 mm in diameter.But there is also a risk of lung cancer when the diameter is less than 8mm,the purpose of this ...
arxiv
The Role of Pepsinogenes and Some Intestinal Hormones in Pathogenesis of Gastroesophageal Reflux Disease [PDF]
80 patients with gastroesophageal reflux disease (GERD) were examined. The diagnosis of GERD was based on the history of the disease, complaints of patients, the results of daily monitoring of pH in the lower third of the esophagus, data of ...
Boichuk, V. (Vira)
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Helicobacter pylori is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, H.
Niluka Gunawardhana+14 more
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Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn [PDF]
Background: Gastrin-releasing peptide (GRP) and its receptor have been shown to play an important role in the sensation of itch. However, although GRP immunoreactivity has been detected in the spinal dorsal horn, there is debate about whether this ...
Gutierrez-Mecinas, Maria+2 more
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