Results 31 to 40 of about 55,603 (271)

Gastrin Protects Against Myocardial Ischemia/Reperfusion Injury via Activation of RISK (Reperfusion Injury Salvage Kinase) and SAFE (Survivor Activating Factor Enhancement) Pathways

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Ischemia/reperfusion injury (IRI) is one of the most predominant complications of ischemic heart disease. Gastrin has emerged as a regulator of cardiovascular function, playing a key protective role in hypoxia.
Xiaoli Yang   +13 more
doaj   +1 more source

CCK‐1 and CCK‐2 receptor agonism do not stimulate GLP‐1 and neurotensin secretion in the isolated perfused rat small intestine or GLP‐1 and PYY secretion in the rat colon

open access: yesPhysiological Reports, 2020
Gastrin and cholecystokinin (CCK) are hormones released from endocrine cells in the antral stomach (gastrin), the duodenum, and the jejunum (CCK). Recent reports, based on secretion experiments in an enteroendocrine cell line (NCI‐H716) and gastrin ...
Ida M. Modvig   +4 more
doaj   +1 more source

The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates [PDF]

open access: yes, 2014
Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: (1) gonadotropin-inhibitory hormone (GnIH), (2) neuropeptide FF (NPFF), (3) pyroglutamylated RFamide peptide (QRFP), (4) prolactin-releasing peptide (
Elphick, MR, Mirabeau, O
core   +1 more source

Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes

open access: yesFrontiers in Endocrinology, 2020
The structurally-related peptides, gastrin and cholecystokinin (CCK), were originally discovered as humoral stimulants of gastric acid secretion and pancreatic enzyme release, respectively.
Qiang Zeng   +3 more
doaj   +1 more source

Spinal neurons that contain gastrin-releasing peptide seldom express Fos or phosphorylate extracellular signal-regulated kinases in response to intradermal chloroquine [PDF]

open access: yes, 2016
Background: Gastrin-releasing peptide (GRP) is thought to play a role in the itch evoked by intradermal injection of chloroquine. Although some early studies suggested that GRP was expressed in pruriceptive primary afferents, it is now thought that GRP ...
Bell, Andrew M.   +3 more
core   +1 more source

IL1B induced Smad 7 negatively regulates gastrin expression. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Helicobacter pylori elicited IL1B is one of the various modulators responsible for perturbation of acid secretion in gut. We have earlier reported that IL1B activated NFkB downregulates gastrin, a major modulator of acid secretion.
Dipanjana Datta De   +6 more
doaj   +1 more source

Solitary pulmonary nodules prediction for lung cancer patients using nomogram and machine learning [PDF]

open access: yesarXiv, 2023
Lung cancer(LC) is a type of malignant neoplasm that originates in the bronchial mucosa or glands.As a clinically common nodule,solitary pulmonary nodules(SPNs) have a significantly higher probability of malignancy when they are larger than 8 mm in diameter.But there is also a risk of lung cancer when the diameter is less than 8mm,the purpose of this ...
arxiv  

The Role of Pepsinogenes and Some Intestinal Hormones in Pathogenesis of Gastroesophageal Reflux Disease [PDF]

open access: yes, 2018
80 patients with gastroesophageal reflux disease (GERD) were examined. The diagnosis of GERD was based on the history of the disease, complaints of patients, the results of daily monitoring of pH in the lower third of the esophagus, data of ...
Boichuk, V. (Vira)
core   +2 more sources

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Helicobacter pylori is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, H.
Niluka Gunawardhana   +14 more
doaj   +1 more source

Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn [PDF]

open access: yes, 2014
Background: Gastrin-releasing peptide (GRP) and its receptor have been shown to play an important role in the sensation of itch. However, although GRP immunoreactivity has been detected in the spinal dorsal horn, there is debate about whether this ...
Gutierrez-Mecinas, Maria   +2 more
core   +1 more source

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