Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells. [PDF]
PLoS ONE, 2014 Macrophage infiltration is a negative prognostic factor for most cancers but gastrointestinal tumors seem to be an exception. The effect of macrophages on cancer progression depends on their phenotype, which may vary between M1 (pro-inflammatory ...
Carlos Hernández +9 more
doaj +5 more sources
Kidney Gastrin/CCKBR Attenuates Type 2 Diabetes Mellitus by Inhibiting SGLT2-Mediated Glucose Reabsorption through Erk/NF-κB Signaling Pathway [PDF]
Diabetes & Metabolism JournalBackground Both sodium-glucose cotransporters (SGLTs) and Na+/H+ exchangers (NHEs) rely on a favorable Na-electrochemical gradient. Gastrin, through the cholecystokinin B receptor (CCKBR), can induce natriuresis and diuresis by inhibiting renal NHEs ...
Xue Zhang +8 more
doaj +2 more sources
A Prospective Study on the Detection of Gastric Neoplasms Using Pepsinogen and Gastrin-17 Levels [PDF]
Gut and LiverBackground/Aims : GastroPanel tests include gastrin-17 (G-17) levels in addition to pepsinogen (PG) and Helicobacter pylori serology tests. The aim of this study was to identify significant test findings in patients with gastric neoplasms by comparing ...
Sun-Young Lee +5 more
doaj +2 more sources
DIAGNOSTIC ACCURACY OF GASTROPANEL® FOR ATROPHIC GASTRITIS IN BRAZILIAN SUBJECTS AND THE EFFECT OF PROTON PUMP INHIBITORS [PDF]
Arquivos de Gastroenterologia, 2020 BACKGROUND: It has been proposed that the combination of gastrin-17 (G-17), pepsinogens I and II (PGI and PGII), and anti-Helicobacter pylori (H. pylori) antibodies (GastroPanel®, BIOHIT HealthCare, Helsinki, Finland) could serve as biomarkers of ...
Rejane MATTAR +5 more
doaj +1 more source
The Lancet, 1965 The Lancet 285 (1965) 816-816.
University of Florida, Gainesville, United States. ( host institution ) +1 more
+6 more sources
Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China [PDF]
Journal of Preventive Medicine and Public Health, 2014 Objectives: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics.
Xiang-Quan Xie +6 more
doaj +1 more source
Biology, 2023 Multiple studies have reported new or exacerbated persistent or resistant hypertension in patients previously infected with COVID-19. We used literature-based discovery to identify and prioritize multi-scalar explanatory biology that relates resistant ...
David Kartchner +7 more
doaj +1 more source
Gut, 1972 Gastrin release in the basal state and following a standard protein meal has been estimated in patients after partial gastrectomy, partial gastrectomy with truncal vagotomy, and total gastrectomy. Following partial gastrectomy, gastrin rose from 8 +/- 0.8 to 20 +/- 3.8 pg/ml with a protein meal. The rise in the partial gastrectomy with truncal vagotomy
M G, Korman, C, Soveny, J, Hansky
openaire +2 more sources
Gastrin, gastrin receptors and colorectal carcinoma [PDF]
Gut, 1998 The possibility that gastrin may play a role in the development of colorectal carcinoma has aroused considerable interest over the past decade. In early reports some colorectal carcinomas and colorectal carcinoma cell lines were shown to produce gastrin,1 to express gastrin receptors,2 and to respond mitogenically to exogenous gastrin.2 The most ...
G S, Baldwin, A, Shulkes
openaire +2 more sources
Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up [PDF]
, 2015 Objective. Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking.
Annibale, Bruno +6 more
core +2 more sources