Results 51 to 60 of about 80,923 (291)
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Central control of gastrointestinal motility [PDF]
Current Opinion in Endocrinology, Diabetes & Obesity, 2019 Purpose of review This review summarizes the organization and structure of vagal neurocircuits controlling the upper gastrointestinal tract, and more recent studies investigating their role in the regulation of gastric motility under physiological, as well as pathophysiological, conditions ...
R. Alberto Travagli +1 more
openaire +3 more sources
Advanced Engineering Materials, EarlyView.Multilayering of TiN film with metallic Ti film is adopted to enhance the fracture resistance of TiN thin films. Plastic dissipation within Ti with process zone size of ≈250 nm, along with elastic–plastic mismatch driven changes to crack driving force enhances the crack growth resistance by ten times, enabling physics informed design of optimized ...
Nidhin George Mathews +5 more
wiley +1 more source
Frontiers in Public HealthBackgroundNo study has assessed the relationship between separation factors and irritable bowel syndrome (IBS). We assess the association between the separation factors and IBS in Chinese left-behind children (LBC).MethodsIn this school-based study, we ...
Zhongcao Wei +20 more
doaj +1 more source
Biofilm Control by Active Topography with Mucin Coating
Advanced Functional Materials, EarlyView.This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han +4 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen +17 more
wiley +1 more source
Neurohumoral control of gastrointestinal motility [PDF]
Reproduction Nutrition Développement, 1980 The progress of gastrointestinal physiology is presently dominated by the concept of neuroendocrine regulation and the control of motility is in keeping with this concept. Progress in biochemistry, immunocytochemistry and radioimmunoassay in the past few years has produced a whole new collection of peptide molecules extracted from the digestive tract ...
openaire +3 more sources
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Role of Lubiprostone on Gastrointestinal Motility [PDF]
Journal of Neurogastroenterology and Motility, 2013 Lubiprostone is a bicyclic fatty acid derivative of prostaglandin E1 used for the treatment of chronic idiopathic constipation and constipation predominant irritable bowel syndrome.1,2 The underlying mechanism of lubiprostone is stimulation of electrogenic chloride secretion by activating chloride channel type-2 (ClC-2)3 and cystic fibrosis ...
openaire +3 more sources