Results 21 to 30 of about 5,047 (245)

A retrospective observational study of the use of gastroprotection for patients on dual antiplatelet therapy in an acute trust in England

open access: yesInternational Journal of Pharmacy Practice, 2022
Dual antiplatelet therapy (DAPT), a combination of aspirin and either clopidogrel, prasugrel or ticagrelor, is recommended for secondary prevention of ischaemic events (heart attack and stroke) in people with coronary artery disease.
E. Wong, L. Bastian, M. Wilcock
semanticscholar   +1 more source

Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice

open access: yesBMC Musculoskeletal Disorders, 2006
Background Gastrointestinal harm, known to occur with NSAIDs, is thought to be lower with NSAID and gastroprotective agent, and with inhibitors selective to cyclooxygenase-2 (coxibs) at usual plasma concentrations.
Phillips Ceri J   +3 more
doaj   +1 more source

Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]

open access: yes, 2006
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko   +6 more
core   +1 more source

Trials of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention Lack Strategies to Ensure Appropriate Gastroprotection.

open access: yesAmerican Journal of Gastroenterology, 2021
INTRODUCTION Gastrointestinal bleeding is a morbid complication of dual antiplatelet therapy (DAPT). We evaluated the extent to which contemporary trials of DAPT included steps to ensure appropriate use of proton pump inhibitor (PPI) gastroprotection and
Jacob E. Kurlander   +7 more
semanticscholar   +1 more source

Protocol for the effective feedback to improve primary care prescribing safety (EFIPPS) study : a cluster randomised controlled trial using ePrescribing data [PDF]

open access: yes, 2012
High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions to improve care are attractive because they are relatively cheap to widely implement. There is good evidence that feedback has small to moderate effects,
Barnett, Karen   +6 more
core   +2 more sources

The gastroprotective effect of ethyl acetate fraction of hot water extract of Trichosanthes cucumerina Linn and its underlying mechanisms

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Antacids, anticholinergic drugs, histamine H2- receptor antagonists and irreversible proton pump inhibitors have been used for the treatment of gastric ulcers. However, prolonged use of these drugs may lead to series of adverse effects such as
Ramani Karunakaran   +4 more
doaj   +1 more source

Bombesin-Induced Gastroprotection

open access: yesAnnals of Surgery, 2005
Bombesin is an endogenous gut peptide that is prominent in the stomach. In addition to its effects on modulating acid and gut peptide secretion, recent evidence indicates that bombesin is a potent gastroprotective agent. This review article examines the ability of bombesin to prevent gastric injury.
Sonlee D, West, David W, Mercer
openaire   +3 more sources

Are the clinical guideline recommendations on gastroprotection being followed? A review in patients taking nonsteroidal anti-inflammatory drugs

open access: yesRevista de Gastroenterología de México (English Edition), 2016
Introduction and aims: The chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) can cause complications in the gastrointestinal tract. The use of proton pump inhibitors (PPIs) is recommended in high-risk patients to prevent them.
J.A. Velasco-Zamora   +2 more
doaj   +1 more source

Gastroprotective Mechanisms

open access: yes, 2022
Gastric ulcer (GU), a common type of peptic ulcer, results from an imbalance in the action of protective and aggressive agents. Gastroprotective mechanisms are mucus layer, gastric epithelium, gastric blood flow, gastric neurons, mucosal repair capacity, and immune system.
Araujo, de Lima, Cirlane Alves   +6 more
openaire   +3 more sources

Lichens: might be considered as a source of gastroprotective molecules? [PDF]

open access: yes, 2013
Indexación: Web of Science; ScieloABSTRACT Lichens are symbiotic relationship between fungi and algae or cyanobacteria. Secondary metabolites from lichens are known as lichen substances.
Areche, Carlos   +3 more
core   +2 more sources

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