Results 31 to 40 of about 5,047 (245)
Molecules, 2021 Introduction: Adiponectin is a hormone secreted by adipocytes, which exhibits insulin-sensitizing and anti-inflammatory properties and acts through adiponectin receptors: AdipoR1 and AdipoR2.
Hubert Zatorski +7 more
doaj +1 more source
Влияние приверженности антисекреторной терапии на риск развития гастропатии, индуцированной приёмом нестероидных противовоспалительных средств [PDF]
, 2019 АНТИСЕКРЕТОРНЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВАИНГИБИТОРЫ ПРОТОННОЙ ПОМПЫГАСТРОПАТИЯПРОТИВОВОСПАЛИТЕЛЬНЫЕ СРЕДСТВА НЕСТЕРОИДНЫЕАНАЛГЕТИКИ ПРОТИВОВОСПАЛИТЕЛЬНЫЕАНТАГОНИСТЫ СИНТЕЗА ПРОСТАГЛАНДИНААСПИРИНОПОДОБНЫЕ СРЕДСТВАЖАРОПОНИЖАЮЩИЕ СРЕДСТВАПРОТИВОРЕВМАТИЧЕСКИЕ ...
Дикарева, Е. А.
core +1 more source
Synthesis and Pharmacological Activity of Diterpenylnaphthoquinone Derivatives
Molecules, 2011 New diterpenylquinones, combining a diterpene diacid and a naphthoquinone, were prepared from junicedric acid and lapachol. The new derivatives were assessed as gastroprotective agents by the HCl-EtOH-induced gastric lesions model in mice as well as for ...
Guillermo Schmeda-Hirschmann +8 more
doaj +1 more source
Risk of Ischaemic Stroke Varies With Antithrombotic Drugs Use in Proton Pump Inhibitor Users: A Self-Controlled Case Series Study. [PDF]
Pharmacoepidemiol Drug SafABSTRACT Background The conflicting findings on the association between proton pump inhibitors (PPIs) and ischaemic stroke could be due to residual confounding. Self‐controlled case series (SCCS) can be used to avoid time‐invariant confounding. Additionally, different baseline risks of stroke should be considered, as some individuals may be prescribed ...
Fan M +7 more
europepmc +2 more sources
Gastroprotection against Rat Ulcers by Nephthea Sterol Derivative
Biomolecules, 2021 Different species belonging to the genus Nephthea (Acyonaceae) are a rich resource for bioactive secondary metabolites. The literature reveals that the gastroprotective effects of marine secondary metabolites have not been comprehensively studied in vivo.
T. Mohamed +11 more
semanticscholar +1 more source
Journal of Drug Delivery and Therapeutics, 2018 NSAIDs suffer from a serious drawback of GI-SEs caused particularly after chronic use. There is evidence concerning the participation of ROS in the etiology & pathophysiology of digestive system disorders like GI-inflammation & gastro ulcer. With the aim to retard the adverse effects of GI-Origin, conjugates of NSAIDs (especially the carboxylic
DN Prasad +2 more
openaire +2 more sources
Frontiers in Pharmacology, 2021 Remote ischemic preconditioning (RIPC) is one of the most effective approaches to attenuate tissue injury caused by severe ischemia-reperfusion (I/R). Experimental studies have demonstrated that RIPC is capable of producing a protective effect not only ...
Ludmila Filaretova +3 more
doaj +1 more source
European journal of internal medicine, 2020 Aspirin and P2Y12 receptor antagonists are widely used across the spectrum of cardiovascular and cerebrovascular diseases. Gastrointestinal complications, including ulcer and bleeding, are relatively common during antiplatelet treatment and, therefore ...
M. Abrignani +16 more
semanticscholar +1 more source
Gastroprotection during the administration of non-steroidal anti-inflammatory drugs. A drug-utilization study [PDF]
, 2004 Producción CientíficaThere has been an increase of anti-ulcer drug consumption in Spain. A high proportion of this consumption may be due to the use of those drugs as gastroprotective agents when co-prescribed with non-steroidal anti-inflammatory drugs ...
Carvajal García-Pando, Alfonso +6 more
core +3 more sources
Adapting clinical guidelines to take account of multimorbidity [PDF]
, 2012 Most people with a chronic condition have multimorbidity, but clinical guidelines almost entirely focus on single conditions. It will never be possible to have good evidence for every possible combination of conditions, but guidelines could be made more ...
Alderson, P. +4 more
core +1 more source